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EV-to-EBITDA is calculated as enterprise value divided by its EBITDA. As of today, Nano Holdings's enterprise value is 円5,664.8 Mil.
Nano Holdings's EBITDA for the trailing twelve months (TTM) ended in Mar. 2026 was 円-994.6 Mil. Therefore, Nano Holdings's EV-to-EBITDA for today is -5.70.
The historical rank and industry rank for Nano Holdings's EV-to-EBITDA or its related term are showing as below:
TSE:4571'
s EV-to-EBITDA Range Over the Past 10 Years
Min: -31.77 Med: -8.29 Max: -2.52
Current: -5.7
During the past 13 years, the highest EV-to-EBITDA of Nano Holdings was -2.52. The lowest was -31.77. And the median was -8.29.
TSE:4571's EV-to-EBITDA is ranked worse than 100% of 402
companies
in the Biotechnology industry
Industry Median: 14.41
vs TSE:4571: -5.70
EV-to-EBITDA is a valuation multiple used in finance and investment to measure the value of a company. This important multiple is often used in conjunction with, or as an alternative to, the PE Ratio to determine the fair market value of a company.
EV-to-EBITDA is a valuation multiple used in finance and investment to measure the value of a company. This important multiple is often used in conjunction with, or as an alternative to, the PE Ratio (TTM) to determine the fair market value of a company.
Nano Holdings's PE Ratio (TTM) for today is calculated as:
Nano Holdings's share price for today is 円109.00.
Nano Holdings's Earnings per Share (Diluted) for the trailing twelve months (TTM) ended in Mar. 2026 adds up the quarterly data reported by the company within the most recent 12 months, which was 円-13.440.
* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD. * For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.
Study has found that the companies with the lowest EV-to-EBITDA outperforms companies measured as cheap by other ratios such as PE Ratio (TTM).
The historical data trend for Nano Holdings's EV-to-EBITDA can be seen below:
* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD. * For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.
TSE:4571 vs VRTX, REGN, RVMD: EV-to-EBITDA Comparison
For the Biotechnology subindustry, Nano Holdings's EV-to-EBITDA, along with its competitors' market caps and EV-to-EBITDA data, can be viewed below:
* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.
Nano Holdings EV-to-EBITDA vs Biotechnology Industry
For the Biotechnology industry and Healthcare sector, Nano Holdings's EV-to-EBITDA distribution charts can be found below:
* The bar in red indicates where Nano Holdings's EV-to-EBITDA falls into.
Nano Holdings's current Enterprise Value is 円5,664.8 Mil.
Nano Holdings's EBITDA for the trailing twelve months (TTM) ended in Mar. 2026 adds up the quarterly data reported by the company within the most recent 12 months, which was 円-994.6 Mil.
* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD. * For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.
Nano Holdings (TSE:4571) has a EV-to-EBITDA of -5.70 as of Aug. 20, 2026. EV to EBITDA ratio is the company's enterprise value divided by earnings before interest, taxes, depreciation and amortization. View historical data on Nano Holdings. According to the industry distribution chart, Nano Holdings ranks #999999 out of 402 companies in the Biotechnology industry.
Is Nano Holdings' EV-to-EBITDA too high?
Nano Holdings' current EV-to-EBITDA is -5.70. Based on the distribution chart, Nano Holdings ranks #999999 out of 402 companies in the Biotechnology industry, which is in the bottom quartile relative to peers. Overall, Nano Holdings has a GF Score™ of 40/100 and is considered Possible Value Trap, reflecting its overall financial health beyond just this single metric.
How does Nano Holdings' EV-to-EBITDA compare to VRTX and REGN?
According to the Biotechnology industry distribution chart, Nano Holdings ranks #999999 out of 402 companies for EV-to-EBITDA. This places Nano Holdings in the lower half of its industry. The industry median EV-to-EBITDA is 14.41. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good EV-to-EBITDA for a Biotechnology company?
The median EV-to-EBITDA among Biotechnology companies is 14.41, based on 402 companies in the industry. Companies in the top quartile (top 25%) have a EV-to-EBITDA significantly above this median, while those in the bottom quartile fall well below. However, EV-to-EBITDA should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high EV-to-EBITDA mean?
A high EV-to-EBITDA can signal that a stock is expensive relative to its fundamentals. EV to EBITDA ratio is the company's enterprise value divided by earnings before interest, taxes, depreciation and amortization. View historical data on Nano Holdings. For the Biotechnology industry, the median EV-to-EBITDA is 14.41 — values significantly above this may indicate overvaluation, while values below may suggest a bargain or underlying issues. Nano Holdings's current EV-to-EBITDA is -5.70. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Nano Holdings stock overvalued right now?
Based on GuruFocus' analysis, Nano Holdings (TSE:4571) is currently considered Possible Value Trap. The stock's GF Value™ is 円186.50, compared to a current price of 円109.00 — trading 41.6% below its estimated fair value. The current EV-to-EBITDA is -5.70. Nano Holdings' overall GF Score™ is 40/100 with 5 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is EV-to-EBITDA calculated?
EV-to-EBITDA is calculated from a company's financial statements. For Nano Holdings (TSE:4571), the current EV-to-EBITDA is -5.70 as of Aug. 20, 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.
Is Nano Holdings (TSE:4571) Overvalued in 2026?
Based on GuruFocus' analysis, Nano Holdings stock appears to be undervalued.
The current stock price of 円109.00 is trading 41.6% below its estimated GF Value™ of 円186.50.
GuruFocus considers Nano Holdings to be Possible Value Trap.
Key valuation signals for TSE:4571:
EV-to-EBITDA: -5.70
GF Value™: 円186.50 vs. price of 円109.00 (41.6% below fair value)
No single metric tells the full story. See the TSE:4571 stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.
Nano Holdings Inc formerly, Nano Mrna Co Ltd is engaged in the research and development of pharmaceuticals using micellar nanoparticle technology. The Group's business is a single segment that involves research and development, manufacturing, and sales of pharmaceuticals and other products, as well as related operations.
40GF Score
Get the complete analysis for TSE:4571
EV-to-EBITDA is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.
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