Nano Holdings (TSE:4571) ROA %: -19.99% (As of Mar. 2026)


TSE:4571 Nano Holdings Inc TSE:4571
43 GF Score
Price 円102.00
GF Value 円187.93
Valuation Possible Value Trap
! 5 Warning Signs
View Full Analysis

What is Nano Holdings ROA %?

Nano Holdings TSE:4571 43 ROA % is -19.99% as of Mar. 2026. GuruFocus rates TSE:4571 with a GF Score™ of 43/100 and a GF Value™ of 円187.93 (Possible Value Trap). The stock has 5 warning signs investors should review. Among 1,413 Biotechnology companies, Nano Holdings ranks better than 59.8% on this metric.

ROA % is calculated as Net Income divided by its average Total Assets over a certain period of time. Nano Holdings's annualized Net Income for the quarter that ended in Mar. 2026 was 円-1,185.8 Mil. Nano Holdings's average Total Assets over the quarter that ended in Mar. 2026 was 円5,930.5 Mil. Therefore, Nano Holdings's annualized ROA % for the quarter that ended in Mar. 2026 was -19.99%.

The historical rank and industry rank for Nano Holdings's ROA % or its related term are showing as below:

TSE:4571' s ROA % Range Over the Past 10 Years
Min: -52.68   Med: -21.31   Max: -14.37
Current: -20.37

During the past 13 years, Nano Holdings's highest ROA % was -14.37%. The lowest was -52.68%. And the median was -21.31%.

TSE:4571's ROA % is ranked better than
59.8% of 1413 companies
in the Biotechnology industry
Industry Median: -32.67 vs TSE:4571: -20.37

Nano Holdings  (TSE:4571) ROA % Explanation

ROA % measures the rate of return on the total assets (shareholder equity plus liabilities). It measures a firm's efficiency at generating profits from shareholders' equity plus its liabilities. ROA % shows how well a company uses what it has to generate earnings. ROA %s can vary drastically across industries. Therefore, ROA % should not be used to compare companies in different industries. For retailers, a ROA % of higher than 5% is expected. For example, Wal-Mart (WMT) has a ROA % of about 8% as of 2012. For banks, ROA % is close to their interest spread. A bank’s ROA % is typically well under 2%.

Similar to ROE, ROA % is affected by profit margins and asset turnover. This can be seen from the Du Pont Formula:

ROA %(Q: Mar. 2026 )
=Net Income/Total Assets
=-1185.776/5930.515
=(Net Income / Revenue)*(Revenue / Total Assets)
=(-1185.776 / 174.228)*(174.228 / 5930.515)
=Net Margin %*Asset Turnover
=-680.59 %*0.0294
=-19.99 %

Note: The Net Income data used here is four times the quarterly (Mar. 2026) net income data. The Revenue data used here is four times the quarterly (Mar. 2026) revenue data.

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.


Be Aware

Like ROE, ROA % is calculated with only 12 months data. Fluctuations in the company's earnings or business cycles can affect the ratio drastically. It is important to look at the ratio from a long term perspective. ROA % can be affected by events such as stock buyback or issuance, and by goodwill, a company's tax rate and its interest payment. ROA % may not reflect the true earning power of the assets. A more accurate measurement is ROC % (ROC).

Many analysts argue the higher return the better. Buffett states that really high ROA % may indicate vulnerability in the durability of the competitive advantage.

E.g. Raising $43b to take on KO is impossible, but $1.7b to take on Moody's is. Although Moody's ROA % and underlying economics is far superior to Coca Cola, the durability is far weaker because of lower entry cost.


Nano Holdings ROA % Related Terms


Nano Holdings ROA % Historical Data

* Premium members only.

The historical data trend for Nano Holdings's ROA % can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Nano Holdings ROA % Chart

Nano Holdings Annual Data
Trend Mar17 Mar18 Mar19 Mar20 Mar21 Mar22 Mar23 Mar24 Mar25 Mar26
ROA %
Get a 7-Day Free Trial Premium Member Only Premium Member Only -25.16 -20.29 -14.37 -18.42 -19.06

Nano Holdings Quarterly Data
Jun21 Sep21 Dec21 Mar22 Jun22 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Sep24 Dec24 Mar25 Jun25 Sep25 Dec25 Mar26
ROA % Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only -23.48 -20.26 -26.18 -17.77 -19.99

TSE:4571 vs VRTX, REGN, ALNY: ROA % Comparison

For the Biotechnology subindustry, Nano Holdings's ROA %, along with its competitors' market caps and ROA % data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


Nano Holdings ROA % vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, Nano Holdings's ROA % distribution charts can be found below:

* The bar in red indicates where Nano Holdings's ROA % falls into.


TSE:4571
43GF Score
Nano Holdings Inc TSE:4571
ROA % is just one metric. See GF Score™, valuation, warning signs, and more.
View Full Analysis

Nano Holdings ROA % Calculation

Nano Holdings's annualized ROA % for the fiscal year that ended in Mar. 2026 is calculated as:

ROA %=Net Income (A: Mar. 2026 )/( (Total Assets (A: Mar. 2025 )+Total Assets (A: Mar. 2026 ))/ count )
=-943.88/( (3996.884+5906.339)/ 2 )
=-943.88/4951.6115
=-19.06 %

Nano Holdings's annualized ROA % for the quarter that ended in Mar. 2026 is calculated as:

ROA %=Net Income (Q: Mar. 2026 )/( (Total Assets (Q: Dec. 2025 )+Total Assets (Q: Mar. 2026 ))/ count )
=-1185.776/( (5954.691+5906.339)/ 2 )
=-1185.776/5930.515
=-19.99 %

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

In the calculation of annual ROA %, the net income of the last fiscal year and the average total assets over the fiscal year are used. In calculating the quarterly data, the Net Income data used here is four times the quarterly (Mar. 2026) net income data. ROA % is displayed in the 30-year financial page.

Frequently Asked Questions Learn more about ROA % →
What does a ROA % of -19.99% mean?
Nano Holdings (TSE:4571) has a ROA % of -19.99% as of Mar. 2026. Return on assets is the ratio of current-period net income to average two-period total assets. View historical data on Nano Holdings and its competitors. According to the industry distribution chart, Nano Holdings ranks #568 out of 1413 companies in the Biotechnology industry, placing it in the top 40.2%.
Is Nano Holdings' ROA % too high?
Nano Holdings' current ROA % is -19.99%. Based on the distribution chart, Nano Holdings ranks #568 out of 1413 companies in the Biotechnology industry, which is above the industry midpoint. Overall, Nano Holdings has a GF Score™ of 43/100 and is considered Possible Value Trap, reflecting its overall financial health beyond just this single metric.
How does Nano Holdings' ROA % compare to VRTX and REGN?
According to the Biotechnology industry distribution chart, Nano Holdings ranks #568 out of 1413 companies for ROA %. This puts Nano Holdings in the upper half of its industry. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good ROA % for a Biotechnology company?
A good ROA % depends on the Biotechnology industry context. However, ROA % should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high ROA % mean?
A high ROA % can signal that a stock is expensive relative to its fundamentals. Return on assets is the ratio of current-period net income to average two-period total assets. View historical data on Nano Holdings and its competitors. Nano Holdings's current ROA % is -19.99%. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Nano Holdings stock overvalued right now?
Based on GuruFocus' analysis, Nano Holdings (TSE:4571) is currently considered Possible Value Trap. The stock's GF Value™ is 円187.93, compared to a current price of 円102.00 — trading 45.7% below its estimated fair value. The current ROA % is -19.99%. Nano Holdings' overall GF Score™ is 43/100 with 5 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is ROA % calculated?
ROA % is calculated from a company's financial statements. For Nano Holdings (TSE:4571), the current ROA % is -19.99% as of Mar. 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Is Nano Holdings (TSE:4571) Overvalued in 2026?

Based on GuruFocus' analysis, Nano Holdings stock appears to be undervalued. The current stock price of 円102.00 is trading 45.7% below its estimated GF Value™ of 円187.93. GuruFocus considers Nano Holdings to be Possible Value Trap.

Key valuation signals for TSE:4571:

  • ROA %: -19.99%
  • GF Value™: 円187.93 vs. price of 円102.00 (45.7% below fair value)
  • GF Score™: 43/100 with 5 warning signs

No single metric tells the full story. See the TSE:4571 stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.


Nano Holdings Business Description

Other Exchanges 3NQ:Germany
Address 2-5-1 Atago, Minato-ku, Chiba, JPN, 277-0882
Nano Holdings Inc formerly, Nano Mrna Co Ltd is engaged in the research and development of pharmaceuticals using micellar nanoparticle technology. The Group's business is a single segment that involves research and development, manufacturing, and sales of pharmaceuticals and other products, as well as related operations.
43GF Score

Get the complete analysis for TSE:4571

ROA % is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

円102.00
Price
円187.93
GF Value