LYEL (Lyell Immunopharma) EPS without NRI: $-8.54 (TTM As of Jun. 2026)

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LYEL Lyell Immunopharma Inc LYEL
53 GF Score
Price $14.72
GF Value $3.71
Valuation Significantly Overvalued
! 6 Warning Signs
View Full Analysis

What is Lyell Immunopharma EPS without NRI?

Lyell Immunopharma LYEL +1.31% 53 EPS without NRI is $-8.54 as of Jun. 2026. GuruFocus rates LYEL with a GF Score™ of 53/100 and a GF Value™ of $3.71 (Significantly Overvalued). The stock has 6 warning signs investors should review. Among 1,160 Biotechnology companies, Lyell Immunopharma ranks worse than 63.97% on this metric.

Lyell Immunopharma's earnings per share without non-recurring items for the three months ended in Jun. 2026 was $-1.92. Its earnings per share without non-recurring items for the trailing twelve months (TTM) ended in Jun. 2026 was $-8.54.

During the past 3 years, the average earnings per share (NRI) Growth Rate was 5.60% per year. During the past 5 years, the average earnings per share (NRI) Growth Rate was 11.90% per year. Please click Growth Rate Calculation Example (GuruFocus) to see how GuruFocus calculates Wal-Mart Stores Inc (WMT)'s revenue growth rate. You can apply the same method to get the EPS without NRI Growth Rate using Earnings per share without Non-Recurring Items (NRI) data.

The historical rank and industry rank for Lyell Immunopharma's EPS without NRI or its related term are showing as below:

LYEL' s 3-Year EPS without NRI Growth Rate Range Over the Past 10 Years
Min: -5.6   Med: 4.25   Max: 22.5
Current: 5.6

During the past 7 years, Lyell Immunopharma's highest 3-Year average Earnings Per Share (NRI) Growth Rate was 22.50% per year. The lowest was -5.60% per year. And the median was 4.25% per year.

LYEL's 3-Year EPS without NRI Growth Rate is ranked worse than
63.97% of 1160 companies
in the Biotechnology industry
Industry Median: 16.05 vs LYEL: 5.60

Lyell Immunopharma's EPS (Diluted) for the three months ended in Jun. 2026 was $-1.92. Its EPS (Diluted) for the trailing twelve months (TTM) ended in Jun. 2026 was $-11.77.

Lyell Immunopharma's EPS (Basic) for the three months ended in Jun. 2026 was $-1.92. Its EPS (Basic) for the trailing twelve months (TTM) ended in Jun. 2026 was $-11.77.


Lyell Immunopharma  (NAS:LYEL) EPS without NRI Explanation

EPS without NRI removes onetime and unusual items from EPS, to provide investors with a more accurate measure of the company’s true earnings. The earnings are adjusted for items that are irregular or unusual in nature, and/or are non-recurring. This is calculated using Net Income (Continuing Operations) plus/minus any tax affected unusual Items and Goodwill Impairments/Write Offs. This can be used to fairly measure a company's profitability.


Be Aware

Compared with Earnings per share, a company's cash flow is better indicator of the company's earnings power.

If a company's earnings per share is less than cash flow per share over long term, investors need to be cautious and find out why.


Lyell Immunopharma EPS without NRI Related Terms


Lyell Immunopharma EPS without NRI Historical Data

* Premium members only.

The historical data trend for Lyell Immunopharma's EPS without NRI can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Lyell Immunopharma EPS without NRI Chart

Lyell Immunopharma Annual Data
Trend Dec19 Dec20 Dec21 Dec22 Dec23 Dec24 Dec25
EPS without NRI
Get a 7-Day Free Trial -31.44 -14.40 -17.67 -14.64 -12.10

Lyell Immunopharma Quarterly Data
Sep21 Dec21 Mar22 Jun22 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Sep24 Dec24 Mar25 Jun25 Sep25 Dec25 Mar26 Jun26
EPS without NRI Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only -2.79 -2.13 -3.39 -1.10 -1.92

LYEL vs FHTX, ZNTL, PALI: EPS without NRI Comparison

For the Biotechnology subindustry, Lyell Immunopharma's PE Ratio without NRI, along with its competitors' market caps and PE Ratio without NRI data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


Lyell Immunopharma PE Ratio without NRI vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, Lyell Immunopharma's PE Ratio without NRI distribution charts can be found below:

* The bar in red indicates where Lyell Immunopharma's PE Ratio without NRI falls into.


LYEL
53GF Score
Lyell Immunopharma Inc LYEL
EPS without NRI is just one metric. See GF Score™, valuation, warning signs, and more.
View Full Analysis

Lyell Immunopharma EPS without NRI Calculation

Earnings Per Share (EPS) is the single most important variable used by Wall Street in determining the earnings power of a company. But investors need to be aware that Earnings per Share can be easily manipulated by adjusting depreciation and amortization rate or non-recurring items. That's why GuruFocus lists EPS without NRI, which better reflects the company's underlying performance.

Earnings Per Share without Non-Recurring Items is the amount of earnings without non-recurring items per outstanding share of the company's stock.

EPS without NRI for the trailing twelve months (TTM) ended in Jun. 2026 adds up the quarterly data reported by the company within the most recent 12 months, which was $-8.54

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Frequently Asked Questions Learn more about EPS without NRI →
What does a EPS without NRI of $-8.54 mean?
Lyell Immunopharma (LYEL) has a EPS without NRI of $-8.54 as of Jun. 2026. EPS without NRI represents per-share earnings excluding one-time charges. View historical data on Lyell Immunopharma and its competitors. According to the industry distribution chart, Lyell Immunopharma ranks #742 out of 1160 companies in the Biotechnology industry, placing it in the top 64%.
Is Lyell Immunopharma's EPS without NRI too high?
Lyell Immunopharma's current EPS without NRI is $-8.54. Based on the distribution chart, Lyell Immunopharma ranks #742 out of 1160 companies in the Biotechnology industry, which is below the industry midpoint. Overall, Lyell Immunopharma has a GF Score™ of 53/100 and is considered Significantly Overvalued, reflecting its overall financial health beyond just this single metric.
How does Lyell Immunopharma's EPS without NRI compare to FHTX and ZNTL?
According to the Biotechnology industry distribution chart, Lyell Immunopharma ranks #742 out of 1160 companies for EPS without NRI. This places Lyell Immunopharma in the lower half of its industry. The industry median EPS without NRI is 16.05. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good EPS without NRI for a Biotechnology company?
The median EPS without NRI among Biotechnology companies is 16.05, based on 1,160 companies in the industry. Companies in the top quartile (top 25%) have a EPS without NRI significantly above this median, while those in the bottom quartile fall well below. However, EPS without NRI should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high EPS without NRI mean?
A high EPS without NRI can signal that a stock is expensive relative to its fundamentals. EPS without NRI represents per-share earnings excluding one-time charges. View historical data on Lyell Immunopharma and its competitors. For the Biotechnology industry, the median EPS without NRI is 16.05 — values significantly above this may indicate overvaluation, while values below may suggest a bargain or underlying issues. Lyell Immunopharma's current EPS without NRI is $-8.54. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Lyell Immunopharma stock overvalued right now?
Based on GuruFocus' analysis, Lyell Immunopharma (LYEL) is currently considered Significantly Overvalued. The stock's GF Value™ is $3.71, compared to a current price of $14.72 — trading 296.8% above its estimated fair value. The current EPS without NRI is $-8.54. Lyell Immunopharma's overall GF Score™ is 53/100 with 6 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is EPS without NRI calculated?
EPS without NRI is calculated from a company's financial statements. For Lyell Immunopharma (LYEL), the current EPS without NRI is $-8.54 as of Jun. 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Is Lyell Immunopharma (LYEL) Overvalued in 2026?

Based on GuruFocus' analysis, Lyell Immunopharma stock appears to be overvalued. The current stock price of $14.72 is trading 296.8% above its estimated GF Value™ of $3.71. GuruFocus considers Lyell Immunopharma to be Significantly Overvalued.

Key valuation signals for LYEL:

  • EPS without NRI: $-8.54
  • GF Value™: $3.71 vs. price of $14.72 (296.8% above fair value)
  • GF Score™: 53/100 with 6 warning signs

No single metric tells the full story. See the LYEL stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.


Lyell Immunopharma Business Description

Address 201 Haskins Way, South San Francisco, CA, USA, 94080
Lyell Immunopharma Inc s a late-stage clinical cell therapy company advancing a pipeline of proprietary next-generation autologous chimeric antigen receptor (CAR) T-cell product candidates for patients with hematologic malignancies and solid tumors. The Company's product candidate, rondecabtagene autoleucel (ronde-cel, also known as LYL314), is an autologous dual-targeting CD19/CD20 CAR T-cell therapy in development for large B-cell lymphoma (LBCL). The Company has recently acquired exclusive rights outside of mainland China, Hong Kong, Macau and Taiwan, to a novel guanylyl cyclase C (GCC)-targeted CAR T-cell product candidate in early clinical development for refractory metastatic colorectal cancer (mCRC) and other GCC-expressing cancers.
53GF Score

Get the complete analysis for LYEL

EPS without NRI is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

$14.72
Price
$3.71
GF Value