PTIX (Protagenic Therapeutics) Equity-to-Asset: -0.54 (As of Dec. 2025)

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PTIX Protagenic Therapeutics Inc PTIX
22 GF Score
Price $0.26
! 2 Warning Signs
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What is Protagenic Therapeutics Equity-to-Asset?

Protagenic Therapeutics PTIX +23.24% 22 Equity-to-Asset is -0.54 as of Dec. 2025. GuruFocus rates PTIX with a GF Score™ of 22/100. The stock has 2 warning signs investors should review. Among 1,417 Biotechnology companies, Protagenic Therapeutics ranks worse than 91.46% on this metric.

Equity to Asset ratio is calculated as total stockholders equity divided by total asset. Protagenic Therapeutics's Total Stockholders Equity for the quarter that ended in Dec. 2025 was $-2.39 Mil. Protagenic Therapeutics's Total Assets for the quarter that ended in Dec. 2025 was $4.43 Mil.

The historical rank and industry rank for Protagenic Therapeutics's Equity-to-Asset or its related term are showing as below:

PTIX' s Equity-to-Asset Range Over the Past 10 Years
Min: -10.12   Med: 0.67   Max: 0.92
Current: -0.54

During the past 13 years, the highest Equity to Asset Ratio of Protagenic Therapeutics was 0.92. The lowest was -10.12. And the median was 0.67.

PTIX's Equity-to-Asset is ranked worse than
91.46% of 1417 companies
in the Biotechnology industry
Industry Median: 0.68 vs PTIX: -0.54

Protagenic Therapeutics  (OTCPK:PTIX) Equity-to-Asset Explanation

Equity to Asset ratio can vary greatly across different industries, as they have different capital structure. A company with smaller Equity to Asset ratio (more leveraged) may have higher ROE % because of the leverage.

For banks, the required minimum Equity to Asset ratio by regulation is 5%. Some stronger banks may have Equity to Asset Ratio of more than 10%.


Protagenic Therapeutics Equity-to-Asset Related Terms


Protagenic Therapeutics Equity-to-Asset Historical Data

* Premium members only.

The historical data trend for Protagenic Therapeutics's Equity-to-Asset can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Protagenic Therapeutics Equity-to-Asset Chart

Protagenic Therapeutics Annual Data
Trend Jun15 Dec16 Dec17 Dec18 Dec19 Dec20 Dec21 Dec22 Dec23 Dec24
Equity-to-Asset
Get a 7-Day Free Trial Premium Member Only Premium Member Only -1.31 0.90 0.86 0.85 0.52

Protagenic Therapeutics Quarterly Data
Mar21 Jun21 Sep21 Dec21 Mar22 Jun22 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Sep24 Dec24 Mar25 Jun25 Sep25 Dec25
Equity-to-Asset Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only 0.52 -0.09 -0.61 -0.94 -0.54

PTIX vs CERO, CYTOF, CARM: Equity-to-Asset Comparison

For the Biotechnology subindustry, Protagenic Therapeutics's Equity-to-Asset, along with its competitors' market caps and Equity-to-Asset data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


Protagenic Therapeutics Equity-to-Asset vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, Protagenic Therapeutics's Equity-to-Asset distribution charts can be found below:

* The bar in red indicates where Protagenic Therapeutics's Equity-to-Asset falls into.


PTIX
22GF Score
Protagenic Therapeutics Inc PTIX
Equity-to-Asset is just one metric. See GF Score™, valuation, warning signs, and more.
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Protagenic Therapeutics Equity-to-Asset Calculation

Equity to Asset ratio measures the ratios of the portion of the asset owned by shareholders out of the total asset. It indicates the leverage of the company, and the amount of debt the company uses in its operation.

Equity to Asset ratio is calculated by dividing total stockholders equity by total asset.

Protagenic Therapeutics's Equity to Asset Ratio for the fiscal year that ended in Dec. 2024 is calculated as

Equity to Asset (A: Dec. 2024 )=Total Stockholders Equity/Total Assets
=1.013/1.956
=

Protagenic Therapeutics's Equity to Asset Ratio for the quarter that ended in Dec. 2025 is calculated as

Equity to Asset (Q: Dec. 2025 )=Total Stockholders Equity/Total Assets
=-2.393/4.431
=

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Frequently Asked Questions Learn more about Equity-to-Asset →
What does a Equity-to-Asset of -0.54 mean?
Protagenic Therapeutics (PTIX) has a Equity-to-Asset of -0.54 as of Dec. 2025. Equity-to-asset ratio equals total company equity divided by total assets. It measures financial leverage. View historical data on Protagenic Therapeutics and its competitors. According to the industry distribution chart, Protagenic Therapeutics ranks #1296 out of 1417 companies in the Biotechnology industry, placing it in the top 91.5%.
Is Protagenic Therapeutics' Equity-to-Asset too high?
Protagenic Therapeutics' current Equity-to-Asset is -0.54. Based on the distribution chart, Protagenic Therapeutics ranks #1296 out of 1417 companies in the Biotechnology industry, which is in the bottom quartile relative to peers. Overall, Protagenic Therapeutics has a GF Score™ of 22/100, reflecting its overall financial health beyond just this single metric.
How does Protagenic Therapeutics' Equity-to-Asset compare to CERO and CYTOF?
According to the Biotechnology industry distribution chart, Protagenic Therapeutics ranks #1296 out of 1417 companies for Equity-to-Asset. This places Protagenic Therapeutics in the lower half of its industry. The industry median Equity-to-Asset is 0.68. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good Equity-to-Asset for a Biotechnology company?
The median Equity-to-Asset among Biotechnology companies is 0.68, based on 1,417 companies in the industry. Companies in the top quartile (top 25%) have a Equity-to-Asset significantly above this median, while those in the bottom quartile fall well below. However, Equity-to-Asset should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high Equity-to-Asset mean?
A high Equity-to-Asset can signal that a stock is expensive relative to its fundamentals. Equity-to-asset ratio equals total company equity divided by total assets. It measures financial leverage. View historical data on Protagenic Therapeutics and its competitors. For the Biotechnology industry, the median Equity-to-Asset is 0.68 — values significantly above this may indicate overvaluation, while values below may suggest a bargain or underlying issues. Protagenic Therapeutics's current Equity-to-Asset is -0.54. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Protagenic Therapeutics stock overvalued right now?
Protagenic Therapeutics (PTIX) has a current Equity-to-Asset of -0.54. The current Equity-to-Asset is -0.54. Protagenic Therapeutics' overall GF Score™ is 22/100 with 2 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is Equity-to-Asset calculated?
Equity-to-Asset is calculated from a company's financial statements. For Protagenic Therapeutics (PTIX), the current Equity-to-Asset is -0.54 as of Dec. 2025. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Protagenic Therapeutics Business Description

Address 149 Fifth Avenue, Suite 500, New York, NY, USA, 10010
Protagenic Therapeutics Inc is a biopharmaceutical company focused on the discovery and development of therapeutics to treat stress-related neuropsychiatric and mood disorders. It provides treatments for mood, anxiety, depression, and neurodegenerative disorders by using peptide-based and brain-active therapeutics. The company's main compound, PT00114, is a synthetic form of Teneurin Carboxy-terminal Associated Peptide, an endogenous brain signaling peptide that can dampen overactive stress responses. It has also created a portfolio of novel neuropeptides that are in various stages of development and preclinical evaluation for the treatment of mood disorders.
22GF Score

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