PTIX (Protagenic Therapeutics) Pre-Tax Income: $-5.16 Mil (TTM As of Dec. 2025)

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PTIX Protagenic Therapeutics Inc PTIX
22 GF Score
Price $1.05
! 2 Warning Signs
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What is Protagenic Therapeutics Pre-Tax Income?

Protagenic Therapeutics PTIX -11.76% 22 Pre-Tax Income is $-5.16 Mil as of Dec. 2025. GuruFocus rates PTIX with a GF Score™ of 22/100. The stock has 2 warning signs investors should review.

Pretax income is the income that a company earns before paying income taxes. Protagenic Therapeutics's pretax income for the three months ended in Dec. 2025 was $2.21 Mil. Its pretax income for the trailing twelve months (TTM) ended in Dec. 2025 was $-5.16 Mil. Protagenic Therapeutics's pretax margin was %.


Protagenic Therapeutics  (OTCPK:PTIX) Pre-Tax Income Explanation

Protagenic Therapeutics's Pretax Margin for the quarter that ended in Dec. 2025 is calculated as

Pretax Margin=Pretax Income/Revenue
=2.211/0
=%

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.


Protagenic Therapeutics Pre-Tax Income Related Terms


Protagenic Therapeutics Pre-Tax Income Historical Data

* Premium members only.

The historical data trend for Protagenic Therapeutics's Pre-Tax Income can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Protagenic Therapeutics Pre-Tax Income Chart

Protagenic Therapeutics Annual Data
Trend Jun14 Jun15 Dec16 Dec17 Dec18 Dec19 Dec20 Dec21 Dec22 Dec23
Pre-Tax Income
Get a 7-Day Free Trial Premium Member Only Premium Member Only -1.75 -2.55 -4.52 -3.56 -5.00

Protagenic Therapeutics Quarterly Data
Mar21 Jun21 Sep21 Dec21 Mar22 Jun22 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Sep24 Dec24 Mar25 Jun25 Sep25 Dec25
Pre-Tax Income Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only -1.55 -1.44 -5.06 -0.87 2.21

PTIX vs SCNI, DCOY, BBLG: Pre-Tax Income Comparison

For the Biotechnology subindustry, Protagenic Therapeutics's Pre-Tax Income, along with its competitors' market caps and Pre-Tax Income data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


Protagenic Therapeutics Pre-Tax Income vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, Protagenic Therapeutics's Pre-Tax Income distribution charts can be found below:

* The bar in red indicates where Protagenic Therapeutics's Pre-Tax Income falls into.


PTIX
22GF Score
Protagenic Therapeutics Inc PTIX
Pre-Tax Income is just one metric. See GF Score™, valuation, warning signs, and more.
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Protagenic Therapeutics Pre-Tax Income Calculation

This is the income that a company earns before paying income taxes.

Protagenic Therapeutics's Pretax Income for the fiscal year that ended in Dec. 2023 is calculated as

Pretax Income=Operating Income+Non Operating Income+Interest Expense+Interest Income+Other
=-4.527+-0.63+-0.108+0.264+0.00099999999999945
=-5.00

Protagenic Therapeutics's Pretax Income for the quarter that ended in Dec. 2025 is calculated as

Pretax Income=Operating Income+Non Operating Income+Interest Expense+Interest Income+Other
=-0.925+3.112+0.023+0.024+-0.023
=2.21

Pre-Tax Income for the trailing twelve months (TTM) ended in Dec. 2025 adds up the quarterly data reported by the company within the most recent 12 months, which was $-5.16 Mil.

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Frequently Asked Questions Learn more about Pre-Tax Income →
What does a Pre-Tax Income of $-5.16 Mil mean?
Protagenic Therapeutics (PTIX) has a Pre-Tax Income of $-5.16 Mil as of Dec. 2025. Pre-Tax Income is the total earnings before taxes but after all operating and interest expenses. View historical data on Protagenic Therapeutics and its competitors.
Is Protagenic Therapeutics' Pre-Tax Income too high?
Protagenic Therapeutics' current Pre-Tax Income is $-5.16 Mil. Overall, Protagenic Therapeutics has a GF Score™ of 22/100, reflecting its overall financial health beyond just this single metric.
How does Protagenic Therapeutics' Pre-Tax Income compare to SCNI and DCOY?
Protagenic Therapeutics' Pre-Tax Income of $-5.16 Mil can be compared against companies in the Biotechnology industry. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good Pre-Tax Income for a Biotechnology company?
A good Pre-Tax Income depends on the Biotechnology industry context. However, Pre-Tax Income should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high Pre-Tax Income mean?
A high Pre-Tax Income can signal that a stock is expensive relative to its fundamentals. Pre-Tax Income is the total earnings before taxes but after all operating and interest expenses. View historical data on Protagenic Therapeutics and its competitors. Protagenic Therapeutics's current Pre-Tax Income is $-5.16 Mil. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Protagenic Therapeutics stock overvalued right now?
Protagenic Therapeutics (PTIX) has a current Pre-Tax Income of $-5.16 Mil. The current Pre-Tax Income is $-5.16 Mil. Protagenic Therapeutics' overall GF Score™ is 22/100 with 2 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is Pre-Tax Income calculated?
Pre-Tax Income is calculated from a company's financial statements. For Protagenic Therapeutics (PTIX), the current Pre-Tax Income is $-5.16 Mil as of Dec. 2025. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Protagenic Therapeutics Business Description

Address 149 Fifth Avenue, Suite 500, New York, NY, USA, 10010
Protagenic Therapeutics Inc is a biopharmaceutical company focused on the discovery and development of therapeutics to treat stress-related neuropsychiatric and mood disorders. It provides treatments for mood, anxiety, depression, and neurodegenerative disorders by using peptide-based and brain-active therapeutics. The company's main compound, PT00114, is a synthetic form of Teneurin Carboxy-terminal Associated Peptide, an endogenous brain signaling peptide that can dampen overactive stress responses. It has also created a portfolio of novel neuropeptides that are in various stages of development and preclinical evaluation for the treatment of mood disorders.
22GF Score

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