OPKO Health (LTS:0KCS) EV-to-FCF: -6.90 (As of Jun. 28, 2026)


LTS:0KCS OPKO Health Inc LTS:0KCS
53 GF Score
Price $1.54
GF Value $1.07
Valuation Significantly Overvalued
! 7 Warning Signs
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What is OPKO Health EV-to-FCF?

OPKO Health LTS:0KCS +3.36% 53 EV-to-FCF is -6.90 as of Jun. 28, 2026. GuruFocus rates LTS:0KCS with a GF Score™ of 53/100 and a GF Value™ of $1.07 (Significantly Overvalued). The stock has 7 warning signs investors should review. Among 97 Medical Diagnostics & Research companies, OPKO Health ranks worse than 1030926.8% on this metric.

EV-to-FCF is calculated as enterprise value divided by its free cash flow. As of today, OPKO Health's Enterprise Value is $1,202.8 Mil. OPKO Health's Free Cash Flow for the trailing twelve months (TTM) ended in Mar. 2026 was $-174.2 Mil. Therefore, OPKO Health's EV-to-FCF for today is -6.90.

The historical rank and industry rank for OPKO Health's EV-to-FCF or its related term are showing as below:

LTS:0KCS' s EV-to-FCF Range Over the Past 10 Years
Min: -278.55   Med: -11.48   Max: 658.79
Current: -6.9

During the past 13 years, the highest EV-to-FCF of OPKO Health was 658.79. The lowest was -278.55. And the median was -11.48.

LTS:0KCS's EV-to-FCF is ranked worse than
100% of 97 companies
in the Medical Diagnostics & Research industry
Industry Median: 22.6 vs LTS:0KCS: -6.90

EV-to-FCF is a valuation multiple that allows analysts and investors to compare stocks, preferably in the same sector or industry. This important multiple is often used in conjunction with, or as an alternative to, the PE Ratio (TTM) to determine the fair market value of a company.

As of today (2026-06-28), OPKO Health's stock price is $1.54. OPKO Health's Earnings per Share (Diluted) for the trailing twelve months (TTM) ended in Mar. 2026 was $-0.270. Therefore, OPKO Health's PE Ratio (TTM) for today is At Loss.


OPKO Health  (LTS:0KCS) EV-to-FCF Explanation

EV-to-FCF is a valuation multiple that allows analysts and investors to compare stocks, preferably in the same sector or industry. This important multiple is often used in conjunction with, or as an alternative to, the PE Ratio (TTM) to determine the fair market value of a company.

OPKO Health's PE Ratio (TTM) for today is calculated as:

PE Ratio (TTM)=Share Price (Today)/Earnings per Share (Diluted) (TTM)
=1.54/-0.270
=At Loss

OPKO Health's share price for today is $1.54.
OPKO Health's Earnings per Share (Diluted) for the trailing twelve months (TTM) ended in Mar. 2026 adds up the quarterly data reported by the company within the most recent 12 months, which was $-0.270.

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Enterprise Value is used because it is a more complete measure in reflecting how much an investor pays when buying a company. Free Cash Flow is an important financial metric because it represents the actual amount of cash at a company's disposal. Companies with a low EV-to-FCF ratio, combined with a strong balance sheet are generally considered as undervalued.


OPKO Health EV-to-FCF Related Terms


OPKO Health EV-to-FCF Historical Data

* Premium members only.

The historical data trend for OPKO Health's EV-to-FCF can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

OPKO Health EV-to-FCF Chart

OPKO Health Annual Data
Trend Dec16 Dec17 Dec18 Dec19 Dec20 Dec21 Dec22 Dec23 Dec24 Dec25
EV-to-FCF
Get a 7-Day Free Trial Premium Member Only Premium Member Only 549.70 -9.34 -31.44 -5.08 -5.16

OPKO Health Quarterly Data
Jun21 Sep21 Dec21 Mar22 Jun22 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Sep24 Dec24 Mar25 Jun25 Sep25 Dec25 Mar26
EV-to-FCF Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only -5.68 -4.45 -5.53 -5.16 -5.26

LTS:0KCS vs PSNL, CDNA, CSTL: EV-to-FCF Comparison

For the Diagnostics & Research subindustry, OPKO Health's EV-to-FCF, along with its competitors' market caps and EV-to-FCF data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


OPKO Health EV-to-FCF vs Medical Diagnostics & Research Industry

For the Medical Diagnostics & Research industry and Healthcare sector, OPKO Health's EV-to-FCF distribution charts can be found below:

* The bar in red indicates where OPKO Health's EV-to-FCF falls into.


LTS:0KCS
53GF Score
OPKO Health Inc LTS:0KCS
EV-to-FCF is just one metric. See GF Score™, valuation, warning signs, and more.
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OPKO Health EV-to-FCF Calculation

OPKO Health's EV-to-FCF for today is calculated as:

EV-to-FCF=Enterprise Value (Today)/Free Cash Flow (TTM)
=1202.786/-174.215
=-6.90

OPKO Health's current Enterprise Value is $1,202.8 Mil.
OPKO Health's Free Cash Flow for the trailing twelve months (TTM) ended in Mar. 2026 adds up the quarterly data reported by the company within the most recent 12 months, which was $-174.2 Mil.

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Frequently Asked Questions Learn more about EV-to-FCF →
What does a EV-to-FCF of -6.90 mean?
OPKO Health (LTS:0KCS) has a EV-to-FCF of -6.90 as of Jun. 28, 2026. EV to FCF ratio is the company's enterprise value divided by free cash flow. View historical data on OPKO Health and its competitors. According to the industry distribution chart, OPKO Health ranks #999999 out of 97 companies in the Medical Diagnostics & Research industry.
Is OPKO Health's EV-to-FCF too high?
OPKO Health's current EV-to-FCF is -6.90. Based on the distribution chart, OPKO Health ranks #999999 out of 97 companies in the Medical Diagnostics & Research industry, which is in the bottom quartile relative to peers. Overall, OPKO Health has a GF Score™ of 53/100 and is considered Significantly Overvalued, reflecting its overall financial health beyond just this single metric.
How does OPKO Health's EV-to-FCF compare to PSNL and CDNA?
According to the Medical Diagnostics & Research industry distribution chart, OPKO Health ranks #999999 out of 97 companies for EV-to-FCF. This places OPKO Health in the lower half of its industry. The industry median EV-to-FCF is 22.60. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good EV-to-FCF for a Medical Diagnostics & Research company?
The median EV-to-FCF among Medical Diagnostics & Research companies is 22.60, based on 97 companies in the industry. Companies in the top quartile (top 25%) have a EV-to-FCF significantly above this median, while those in the bottom quartile fall well below. However, EV-to-FCF should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high EV-to-FCF mean?
A high EV-to-FCF can signal that a stock is expensive relative to its fundamentals. EV to FCF ratio is the company's enterprise value divided by free cash flow. View historical data on OPKO Health and its competitors. For the Medical Diagnostics & Research industry, the median EV-to-FCF is 22.60 — values significantly above this may indicate overvaluation, while values below may suggest a bargain or underlying issues. OPKO Health's current EV-to-FCF is -6.90. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is OPKO Health stock overvalued right now?
Based on GuruFocus' analysis, OPKO Health (LTS:0KCS) is currently considered Significantly Overvalued. The stock's GF Value™ is $1.07, compared to a current price of $1.54 — trading 43.9% above its estimated fair value. The current EV-to-FCF is -6.90. OPKO Health's overall GF Score™ is 53/100 with 7 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is EV-to-FCF calculated?
EV-to-FCF is calculated from a company's financial statements. For OPKO Health (LTS:0KCS), the current EV-to-FCF is -6.90 as of Jun. 28, 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Is OPKO Health (LTS:0KCS) Overvalued in 2026?

Based on GuruFocus' analysis, OPKO Health stock appears to be overvalued. The current stock price of $1.54 is trading 43.9% above its estimated GF Value™ of $1.07. GuruFocus considers OPKO Health to be Significantly Overvalued.

Key valuation signals for LTS:0KCS:

  • EV-to-FCF: -6.90
  • GF Value™: $1.07 vs. price of $1.54 (43.9% above fair value)
  • GF Score™: 53/100 with 7 warning signs

No single metric tells the full story. See the LTS:0KCS stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.


OPKO Health Business Description

Address 4400 Biscayne Boulevard, Miami, FL, USA, 33137
OPKO Health Inc is a diversified biotechnology company that operates pharmaceutical and diagnostic development programs. Its segments include pharmaceutical and diagnostics. The Pharmaceutical segment consists of its pharmaceutical operations in Chile, Mexico, Ireland, Israel, Spain, Ecuador, France, the United States, and its pharmaceutical research and development operations. The Diagnostics segment consists of clinical and genomics laboratory operations through BioReference and point-of-care operations. It generates the majority of its revenue from the Diagnostics segment.
53GF Score

Get the complete analysis for LTS:0KCS

EV-to-FCF is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

$1.54
Price
$1.07
GF Value