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Richard Sloan from the University of Michigan was first to document what is referred to as the "accrual anomaly". His 1996 paper found that shares of companies with small or negative accruals vastly outperform (+10%) those of companies with large ones.
Annexon's Sloan Ratio for the quarter that ended in Mar. 2026 was -50.54%.
Warning Sign:
When sloan ratio (-75.8)% higher than 25% or lower than -25%, earnings are more likely to be made up of accruals.
As of Mar. 2026, Annexon has a Sloan Ratio of -50.54%, indicating earnings are more likely to be made up of accruals.
A former University of Michigan researcher, Richard Sloan's 1996 paper found that shares of companies with small or negative accruals vastly outperform (+10%) those of companies with large ones. In fact, for the 40-year period between 1962 and 2001, buying the lowest accrual companies and shorting the highest accrual companies resulted in an average annual compounded return of 18%, more than double the S&P 500's 7.4% annual return over the same period.
If the Sloan Ratio is between -10% and 10%, the company is in the safe zone and there is no funny business with accruals.
If the Sloan Ratio is less than between -25% and -10% on the negative side, and between 10% and 25% on the positive side, this is a warning stage of accrual build up.
If the Sloan Ratio is less than -25% or greater than 25%, and this ratio is consistent over several quarters or even years, be careful. Earnings are highly likely to be made up of accruals.
As of Mar. 2026, Annexon has a Sloan Ratio of -50.54%, indicating earnings are more likely to be made up of accruals.
Annexon Sloan Ratio % Related Terms
Annexon Sloan Ratio % Historical Data
* Premium members only.
The historical data trend for Annexon's Sloan Ratio % can be seen below:
* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD. * For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.
ANNX vs ABUS, TBPH, SANA: Sloan Ratio % Comparison
For the Biotechnology subindustry, Annexon's Sloan Ratio %, along with its competitors' market caps and Sloan Ratio % data, can be viewed below:
* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.
Annexon Sloan Ratio % vs Biotechnology Industry
For the Biotechnology industry and Healthcare sector, Annexon's Sloan Ratio % distribution charts can be found below:
* The bar in red indicates where Annexon's Sloan Ratio % falls into.
Earnings contain a lot of non cash earnings which is called accruals. The Sloan ratio is a way to identify firms with low non-cash or accrual-derived earnings relative to their cash flow.
Annexon's Sloan Ratio for the fiscal year that ended in Dec. 2025 is calculated as
Annexon's Net Income for the trailing twelve months (TTM) ended in Mar. 2026 was -49.156 (Jun. 2025 ) + -54.922 (Sep. 2025 ) + -48.256 (Dec. 2025 ) + -44.142 (Mar. 2026 ) = $-196.48 Mil.
Annexon's Cash Flow from Operations for the trailing twelve months (TTM) ended in Mar. 2026 was -38.071 (Jun. 2025 ) + -52.304 (Sep. 2025 ) + -45.926 (Dec. 2025 ) + -46.796 (Mar. 2026 ) = $-183.10 Mil.
Annexon's Cash Flow from Investing for the trailing twelve months (TTM) ended in Mar. 2026 was 73.082 (Jun. 2025 ) + 45.871 (Sep. 2025 ) + -26.521 (Dec. 2025 ) + 27.056 (Mar. 2026 ) = $119.49 Mil.
* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD. * For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.
Annexon (ANNX) has a Sloan Ratio % of -50.54% as of Mar. 2026. Sloan ratio measures earnings quality based on the amount of accruals. View historical data on Annexon and its competitors.
Is Annexon's Sloan Ratio % too high?
Annexon's current Sloan Ratio % is -50.54%. Overall, Annexon has a GF Score™ of 34/100, reflecting its overall financial health beyond just this single metric.
How does Annexon's Sloan Ratio % compare to ABUS and TBPH?
Annexon's Sloan Ratio % of -50.54% can be compared against companies in the Biotechnology industry. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good Sloan Ratio % for a Biotechnology company?
A good Sloan Ratio % depends on the Biotechnology industry context. However, Sloan Ratio % should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high Sloan Ratio % mean?
A high Sloan Ratio % can signal that a stock is expensive relative to its fundamentals. Sloan ratio measures earnings quality based on the amount of accruals. View historical data on Annexon and its competitors. Annexon's current Sloan Ratio % is -50.54%. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Annexon stock overvalued right now?
Annexon (ANNX) has a current Sloan Ratio % of -50.54%. The current Sloan Ratio % is -50.54%. Annexon's overall GF Score™ is 34/100 with 2 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is Sloan Ratio % calculated?
Sloan Ratio % is calculated from a company's financial statements. For Annexon (ANNX), the current Sloan Ratio % is -50.54% as of Mar. 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.
Annexon Inc is a clinical-stage biopharmaceutical company developing a pipeline of novel therapies for patients with classical complement-mediated disorders of the body, brain, and eye. Its pipeline is based on its platform technology addressing well-researched classical complement-mediated autoimmune and neurodegenerative disease processes, both of which are triggered by aberrant activation of C1q. Its pipeline of product candidates is designed to block the activity of C1q and the entire classical complement pathway in a broad set of complement-mediated diseases. Its product candidates are ANX005, for autoimmune & neurodegenerative disorders; ANX007, for neurodegenerative ophthalmic disorders; ANX1502, for Oral small molecule; and ANX009, for systemic autoimmune diseases.
34GF Score
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