ORPOF (OSE Immunotherapeutics) 3-Year Book Growth Rate: -11.20% (As of Dec. 2025)

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ORPOF OSE Immunotherapeutics SA ORPOF
43 GF Score
Price $4.43
GF Value $2.32
! 6 Warning Signs
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What is OSE Immunotherapeutics 3-Year Book Growth Rate?

OSE Immunotherapeutics ORPOF 43 3-Year Book Growth Rate is -11.20% as of Dec. 2025. GuruFocus rates ORPOF with a GF Score™ of 43/100 and a GF Value™ of $2.32. The stock has 6 warning signs investors should review. Among 1,123 Biotechnology companies, OSE Immunotherapeutics ranks worse than 52.98% on this metric.

OSE Immunotherapeutics's Book Value per Share for the quarter that ended in Dec. 2025 was $1.43.

During the past 12 months, OSE Immunotherapeutics's average Book Value per Share Growth Rate was -57.50% per year. During the past 3 years, the average Book Value per Share Growth Rate was -11.20% per year. During the past 5 years, the average Book Value per Share Growth Rate was -13.90% per year. During the past 10 years, the average Book Value per Share Growth Rate was -7.40% per year. Please click Growth Rate Calculation Example (GuruFocus) to see how GuruFocus calculates Wal-Mart Stores Inc (WMT)'s revenue growth rate. You can apply the same method to get the average Book Value per Share growth rate.

During the past 13 years, the highest 3-Year average Book Value per Share Growth Rate of OSE Immunotherapeutics was 42.50% per year. The lowest was -32.20% per year. And the median was -7.85% per year.


OSE Immunotherapeutics  (OTCPK:ORPOF) 3-Year Book Growth Rate Explanation

Book Value per Share is the ratio of equity available to common shareholders divided by the shares outstanding. Book value per share effectively indicates a firm's net asset value on a per-share basis. It can be used by investors to gauge whether a stock price is undervalued by comparing it to the firm's market value per share. Theoretically, it is what the shareholders will receive if the company is liquidated.


OSE Immunotherapeutics 3-Year Book Growth Rate Related Terms


ORPOF vs VRTX, REGN, MRNA: 3-Year Book Growth Rate Comparison

For the Biotechnology subindustry, OSE Immunotherapeutics's 3-Year Book Growth Rate, along with its competitors' market caps and 3-Year Book Growth Rate data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


OSE Immunotherapeutics 3-Year Book Growth Rate vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, OSE Immunotherapeutics's 3-Year Book Growth Rate distribution charts can be found below:

* The bar in red indicates where OSE Immunotherapeutics's 3-Year Book Growth Rate falls into.


ORPOF
43GF Score
OSE Immunotherapeutics SA ORPOF
3-Year Book Growth Rate is just one metric. See GF Score™, valuation, warning signs, and more.
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OSE Immunotherapeutics 3-Year Book Growth Rate Calculation

This is the 3-year average growth rate of Book Value per Share. The growth rate is calculated using exponential compounding based on the latest four year annual data.

Please click Growth Rate Calculation Example (GuruFocus) to see how GuruFocus calculates Wal-Mart Stores Inc (WMT)'s revenue growth rate. You can apply the same method to get the average Book Value per Share growth rate.

What does a 3-Year Book Growth Rate of -11.20% mean?
OSE Immunotherapeutics (ORPOF) has a 3-Year Book Growth Rate of -11.20% as of Dec. 2025. 3-Year Book Growth Rate is the 3-year average growth rate of Book Value per Share. View historical data for OSE Immunotherapeutics and its competitors. According to the industry distribution chart, OSE Immunotherapeutics ranks #595 out of 1123 companies in the Biotechnology industry, placing it in the top 53%.
Is OSE Immunotherapeutics' 3-Year Book Growth Rate too high?
OSE Immunotherapeutics' current 3-Year Book Growth Rate is -11.20%. Based on the distribution chart, OSE Immunotherapeutics ranks #595 out of 1123 companies in the Biotechnology industry, which is below the industry midpoint. Overall, OSE Immunotherapeutics has a GF Score™ of 43/100, reflecting its overall financial health beyond just this single metric.
How does OSE Immunotherapeutics' 3-Year Book Growth Rate compare to VRTX and REGN?
According to the Biotechnology industry distribution chart, OSE Immunotherapeutics ranks #595 out of 1123 companies for 3-Year Book Growth Rate. This places OSE Immunotherapeutics in the lower half of its industry. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good 3-Year Book Growth Rate for a Biotechnology company?
A good 3-Year Book Growth Rate depends on the Biotechnology industry context. However, 3-Year Book Growth Rate should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high 3-Year Book Growth Rate mean?
A high 3-Year Book Growth Rate can signal that a stock is expensive relative to its fundamentals. 3-Year Book Growth Rate is the 3-year average growth rate of Book Value per Share. View historical data for OSE Immunotherapeutics and its competitors. OSE Immunotherapeutics's current 3-Year Book Growth Rate is -11.20%. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is OSE Immunotherapeutics stock overvalued right now?
OSE Immunotherapeutics (ORPOF) has a current 3-Year Book Growth Rate of -11.20%. The stock's GF Value™ is $2.32, compared to a current price of $4.43 — trading 90.9% above its estimated fair value. The current 3-Year Book Growth Rate is -11.20%. OSE Immunotherapeutics' overall GF Score™ is 43/100 with 6 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is 3-Year Book Growth Rate calculated?
3-Year Book Growth Rate is calculated from a company's financial statements. For OSE Immunotherapeutics (ORPOF), the current 3-Year Book Growth Rate is -11.20% as of Dec. 2025. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Is OSE Immunotherapeutics (ORPOF) Overvalued in 2026?

Based on GuruFocus' analysis, OSE Immunotherapeutics stock appears to be overvalued. The current stock price of $4.43 is trading 90.9% above its estimated GF Value™ of $2.32.

Key valuation signals for ORPOF:

  • 3-Year Book Growth Rate: -11.20%
  • GF Value™: $2.32 vs. price of $4.43 (90.9% above fair value)
  • GF Score™: 43/100 with 6 warning signs

No single metric tells the full story. See the ORPOF stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.


OSE Immunotherapeutics Business Description

Address 22, Boulevard Benoni Goullin, Nantes, FRA, 44200
OSE Immunotherapeutics SA is a France-based biotechnology company focused on the development of immunotherapies for immune activation and regulation in the fields of immuno-oncology and autoimmune diseases. The product portfolio of the company comprises Tedopi, OSE-172, OSE-703, FR104 and OSE-127.
43GF Score

Get the complete analysis for ORPOF

3-Year Book Growth Rate is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

$4.43
Price
$2.32
GF Value