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OSE ImmunotherapeuticsORPOF 51 Forward PE Ratio is 105.48 as of Jul. 14, 2026. GuruFocus rates ORPOF with a GF Score™ of 51/100 and a GF Value™ of $3.33 (Significantly Overvalued). The stock has 6 warning signs investors should review. Among 354 Biotechnology companies, OSE Immunotherapeutics ranks worse than 87.85% on this metric.
OSE Immunotherapeutics (OTCPK:ORPOF) Forward PE Ratio Explanation
The Forward PE Ratio of a company is often used to compare current earnings to estimated future earnings, as well as gaining a clearer picture of what earnings will look like without charges and other accounting adjustments. If earnings are expected to grow in the future, the Forward PE Ratio will be lower than the current PE Ratio. This measure is also used to compare one company to another with a forward-looking focus.
Trailing PE Ratio relies on what is already done. It uses the current share price and divides by the total EPS (Basic) over the past 12 months. PE Ratio can be affected by Non Operating Income such as the sale of part of businesses. This may increase for the current year or quarter dramatically. But it cannot be repeated over and over. Therefore PE Ratio without NRI is a more accurate indication of valuation than PE Ratio .
OSE Immunotherapeutics Forward PE Ratio Related Terms
OSE Immunotherapeutics Forward PE Ratio Historical Data
* Premium members only.
The historical data trend for OSE Immunotherapeutics's Forward PE Ratio can be seen below:
* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD. * For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.
OSE Immunotherapeutics Forward PE Ratio Chart
OSE Immunotherapeutics Annual Data
Trend
2025-12
Forward PE Ratio
276.19
OSE Immunotherapeutics Semi-Annual Data
2019-06
2025-12
Forward PE Ratio
9.95
276.19
ORPOF vs VRTX, REGN, ALNY: Forward PE Ratio Comparison
For the Biotechnology subindustry, OSE Immunotherapeutics's Forward PE Ratio, along with its competitors' market caps and Forward PE Ratio data, can be viewed below:
* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.
OSE Immunotherapeutics Forward PE Ratio vs Biotechnology Industry
For the Biotechnology industry and Healthcare sector, OSE Immunotherapeutics's Forward PE Ratio distribution charts can be found below:
* The bar in red indicates where OSE Immunotherapeutics's Forward PE Ratio falls into.
OSE Immunotherapeutics Forward PE Ratio Calculation
It's a measure of the price-to-earnings ratio (PE Ratio) using forecasted earnings for the calculation. While the earnings used are just an estimate and are not as reliable as current earnings data, there is still benefit in estimated P/E analysis. The forecasted earnings used in the formula can either be for the next 12 months or for the next full-year fiscal period.
OSE Immunotherapeutics (ORPOF) has a Forward PE Ratio of 105.48 as of Jul. 14, 2026. Forward P/E ratio is the share price dividend by the expected per-share earnings in the next 12 months. View historical data on OSE Immunotherapeutics and its competitors. According to the industry distribution chart, OSE Immunotherapeutics ranks #311 out of 354 companies in the Biotechnology industry, placing it in the top 87.9%.
Is OSE Immunotherapeutics' Forward PE Ratio too high?
OSE Immunotherapeutics' current Forward PE Ratio is 105.48. The Biotechnology industry median Forward PE Ratio is 22.13. OSE Immunotherapeutics' value of 105.48 is 376.7% above this industry median. Based on the distribution chart, OSE Immunotherapeutics ranks #311 out of 354 companies in the Biotechnology industry, which is in the bottom quartile relative to peers. Overall, OSE Immunotherapeutics has a GF Score™ of 51/100 and is considered Significantly Overvalued, reflecting its overall financial health beyond just this single metric.
How does OSE Immunotherapeutics' Forward PE Ratio compare to VRTX and REGN?
According to the Biotechnology industry distribution chart, OSE Immunotherapeutics ranks #311 out of 354 companies for Forward PE Ratio. This places OSE Immunotherapeutics in the lower half of its industry. The industry median Forward PE Ratio is 22.13. OSE Immunotherapeutics' value of 105.48 is 376.7% above this benchmark. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good Forward PE Ratio for a Biotechnology company?
The median Forward PE Ratio among Biotechnology companies is 22.13, based on 354 companies in the industry. Companies in the top quartile (top 25%) have a Forward PE Ratio significantly above this median, while those in the bottom quartile fall well below. However, Forward PE Ratio should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. OSE Immunotherapeutics's current Forward PE Ratio of 105.48 is 376.7% above the industry median. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high Forward PE Ratio mean?
A high Forward PE Ratio can signal that a stock is expensive relative to its fundamentals. Forward P/E ratio is the share price dividend by the expected per-share earnings in the next 12 months. View historical data on OSE Immunotherapeutics and its competitors. For the Biotechnology industry, the median Forward PE Ratio is 22.13 — values significantly above this may indicate overvaluation, while values below may suggest a bargain or underlying issues. OSE Immunotherapeutics's current Forward PE Ratio is 105.48. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is OSE Immunotherapeutics stock overvalued right now?
Based on GuruFocus' analysis, OSE Immunotherapeutics (ORPOF) is currently considered Significantly Overvalued. The stock's GF Value™ is $3.33, compared to a current price of $4.43 — trading 33% above its estimated fair value. The current Forward PE Ratio is 105.48 and 376.7% above the Biotechnology industry median of 22.13. OSE Immunotherapeutics' overall GF Score™ is 51/100 with 6 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is Forward PE Ratio calculated?
Forward PE Ratio is calculated from a company's financial statements. For OSE Immunotherapeutics (ORPOF), the current Forward PE Ratio is 105.48 as of Jul. 14, 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.
Is OSE Immunotherapeutics (ORPOF) Overvalued in 2026?
Based on GuruFocus' analysis, OSE Immunotherapeutics stock appears to be overvalued.
The current stock price of $4.43 is trading 33% above its estimated GF Value™ of $3.33.
GuruFocus considers OSE Immunotherapeutics to be Significantly Overvalued.
Key valuation signals for ORPOF:
Forward PE Ratio: 105.48
GF Value™: $3.33 vs. price of $4.43 (33% above fair value)
Industry Position: 376.7% above the Biotechnology median (#311 of 354)
No single metric tells the full story. See the ORPOF stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.
OSE Immunotherapeutics SA is a France-based biotechnology company focused on the development of immunotherapies for immune activation and regulation in the fields of immuno-oncology and autoimmune diseases. The product portfolio of the company comprises Tedopi, OSE-172, OSE-703, FR104 and OSE-127.
51GF Score
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Forward PE Ratio is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.
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