ORPOF (OSE Immunotherapeutics) 3-Year EPS without NRI Growth Rate: -18.10% (As of Dec. 2025)

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ORPOF OSE Immunotherapeutics SA ORPOF
41 GF Score
Price $4.43
GF Value $2.12
! 6 Warning Signs
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What is OSE Immunotherapeutics 3-Year EPS without NRI Growth Rate?

OSE Immunotherapeutics ORPOF 41 3-Year EPS without NRI Growth Rate is -18.10% as of Dec. 2025. GuruFocus rates ORPOF with a GF Score™ of 41/100 and a GF Value™ of $2.12. The stock has 6 warning signs investors should review. Among 1,160 Biotechnology companies, OSE Immunotherapeutics ranks worse than 84.48% on this metric.

OSE Immunotherapeutics's EPS without NRI for the six months ended in Dec. 2025 was $-2.75.

During the past 12 months, OSE Immunotherapeutics's average EPS without NRI Growth Rate was -213.40% per year. During the past 3 years, the average EPS without NRI Growth Rate was -18.10% per year. Please click Growth Rate Calculation Example (GuruFocus) to see how GuruFocus calculates Wal-Mart Stores Inc (WMT)'s revenue growth rate. You can apply the same method to get the average EPS without NRI growth rate.

During the past 13 years, the highest 3-Year average EPS without NRI Growth Rate of OSE Immunotherapeutics was -6.20% per year. The lowest was -49.80% per year. And the median was -22.40% per year.


OSE Immunotherapeutics  (OTCPK:ORPOF) 3-Year EPS without NRI Growth Rate Explanation

EPS without NRI is the amount of earnings without non-recurring items per outstanding share of the company's stock.

Earnings Per Share (EPS) is the single most important variable used by Wall Street in determining the earnings power of a company. But investors need to be aware that Earnings per Share can be easily manipulated by adjusting depreciation and amortization rate or non-recurring items. That's why GuruFocus lists Earnings per share without Non-Recurring Items, which better reflects the company's underlying performance.


OSE Immunotherapeutics 3-Year EPS without NRI Growth Rate Related Terms


ORPOF vs VRTX, REGN, MRNA: 3-Year EPS without NRI Growth Rate Comparison

For the Biotechnology subindustry, OSE Immunotherapeutics's 3-Year EPS without NRI Growth Rate, along with its competitors' market caps and 3-Year EPS without NRI Growth Rate data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


OSE Immunotherapeutics 3-Year EPS without NRI Growth Rate vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, OSE Immunotherapeutics's 3-Year EPS without NRI Growth Rate distribution charts can be found below:

* The bar in red indicates where OSE Immunotherapeutics's 3-Year EPS without NRI Growth Rate falls into.


ORPOF
41GF Score
OSE Immunotherapeutics SA ORPOF
3-Year EPS without NRI Growth Rate is just one metric. See GF Score™, valuation, warning signs, and more.
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OSE Immunotherapeutics 3-Year EPS without NRI Growth Rate Calculation

This is the 3-year average growth rate of EPS without NRI. The growth rate is calculated using exponential compounding based on the latest four year annual data.

Please click Growth Rate Calculation Example (GuruFocus) to see how GuruFocus calculates Wal-Mart Stores Inc (WMT)'s revenue growth rate. You can apply the same method to get the average EPS without NRI growth rate.

What does a 3-Year EPS without NRI Growth Rate of -18.10% mean?
OSE Immunotherapeutics (ORPOF) has a 3-Year EPS without NRI Growth Rate of -18.10% as of Dec. 2025. 3-Year EPS without NRI Growth Rate is the 3-year average growth rate of EPS without NRI. View historical data for OSE Immunotherapeutics and its competitors. According to the industry distribution chart, OSE Immunotherapeutics ranks #980 out of 1160 companies in the Biotechnology industry, placing it in the top 84.5%.
Is OSE Immunotherapeutics' 3-Year EPS without NRI Growth Rate too high?
OSE Immunotherapeutics' current 3-Year EPS without NRI Growth Rate is -18.10%. Based on the distribution chart, OSE Immunotherapeutics ranks #980 out of 1160 companies in the Biotechnology industry, which is in the bottom quartile relative to peers. Overall, OSE Immunotherapeutics has a GF Score™ of 41/100, reflecting its overall financial health beyond just this single metric.
How does OSE Immunotherapeutics' 3-Year EPS without NRI Growth Rate compare to VRTX and REGN?
According to the Biotechnology industry distribution chart, OSE Immunotherapeutics ranks #980 out of 1160 companies for 3-Year EPS without NRI Growth Rate. This places OSE Immunotherapeutics in the lower half of its industry. The industry median 3-Year EPS without NRI Growth Rate is 16.05. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good 3-Year EPS without NRI Growth Rate for a Biotechnology company?
The median 3-Year EPS without NRI Growth Rate among Biotechnology companies is 16.05, based on 1,160 companies in the industry. Companies in the top quartile (top 25%) have a 3-Year EPS without NRI Growth Rate significantly above this median, while those in the bottom quartile fall well below. However, 3-Year EPS without NRI Growth Rate should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high 3-Year EPS without NRI Growth Rate mean?
A high 3-Year EPS without NRI Growth Rate can signal that a stock is expensive relative to its fundamentals. 3-Year EPS without NRI Growth Rate is the 3-year average growth rate of EPS without NRI. View historical data for OSE Immunotherapeutics and its competitors. For the Biotechnology industry, the median 3-Year EPS without NRI Growth Rate is 16.05 — values significantly above this may indicate overvaluation, while values below may suggest a bargain or underlying issues. OSE Immunotherapeutics's current 3-Year EPS without NRI Growth Rate is -18.10%. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is OSE Immunotherapeutics stock overvalued right now?
OSE Immunotherapeutics (ORPOF) has a current 3-Year EPS without NRI Growth Rate of -18.10%. The stock's GF Value™ is $2.12, compared to a current price of $4.43 — trading 109% above its estimated fair value. The current 3-Year EPS without NRI Growth Rate is -18.10%. OSE Immunotherapeutics' overall GF Score™ is 41/100 with 6 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is 3-Year EPS without NRI Growth Rate calculated?
3-Year EPS without NRI Growth Rate is calculated from a company's financial statements. For OSE Immunotherapeutics (ORPOF), the current 3-Year EPS without NRI Growth Rate is -18.10% as of Dec. 2025. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Is OSE Immunotherapeutics (ORPOF) Overvalued in 2026?

Based on GuruFocus' analysis, OSE Immunotherapeutics stock appears to be overvalued. The current stock price of $4.43 is trading 109% above its estimated GF Value™ of $2.12.

Key valuation signals for ORPOF:

  • 3-Year EPS without NRI Growth Rate: -18.10%
  • GF Value™: $2.12 vs. price of $4.43 (109% above fair value)
  • GF Score™: 41/100 with 6 warning signs

No single metric tells the full story. See the ORPOF stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.


OSE Immunotherapeutics Business Description

Address 22, Boulevard Benoni Goullin, Nantes, FRA, 44200
OSE Immunotherapeutics SA is a France-based biotechnology company focused on the development of immunotherapies for immune activation and regulation in the fields of immuno-oncology and autoimmune diseases. The product portfolio of the company comprises Tedopi, OSE-172, OSE-703, FR104 and OSE-127.
41GF Score

Get the complete analysis for ORPOF

3-Year EPS without NRI Growth Rate is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

$4.43
Price
$2.12
GF Value