ORPOF (OSE Immunotherapeutics) OCF Yield %: -41.50 (As of Jun. 27, 2026)


ORPOF OSE Immunotherapeutics SA ORPOF
41 GF Score
Price $4.43
GF Value $3.36
Valuation Significantly Overvalued
! 6 Warning Signs
View Full Analysis

What is OSE Immunotherapeutics OCF Yield %?

OSE Immunotherapeutics ORPOF 41 OCF Yield % is -41.50 as of Jun. 27, 2026. GuruFocus rates ORPOF with a GF Score™ of 41/100 and a GF Value™ of $3.36 (Significantly Overvalued). The stock has 6 warning signs investors should review. Among 1,419 Biotechnology companies, OSE Immunotherapeutics ranks worse than 80.62% on this metric.

OCF Yield % is calculated as Cash Flow from Operations divided by Market Capitalization. It is a financial solvency ratio that compares the operating cash flow a company is expected to earn against its market value.

As of today, OSE Immunotherapeutics's Trailing 12-Month Cash Flow from Operations is $-39.52 Mil, and Market Cap is $83.94 Mil. Therefore, OSE Immunotherapeutics's OCF Yield % for today is -41.50%.

The historical rank and industry rank for OSE Immunotherapeutics's OCF Yield % or its related term are showing as below:

ORPOF' s OCF Yield % Range Over the Past 10 Years
Min: -50.5   Med: -8.26   Max: 38.45
Current: -41.5


During the past 13 years, the highest OCF Yield % of OSE Immunotherapeutics was 38.45%. The lowest was -50.50%. And the median was -8.26%.

ORPOF's OCF Yield % is ranked worse than
80.62% of 1419 companies
in the Biotechnology industry
Industry Median: -8.48 vs ORPOF: -41.50

OSE Immunotherapeutics's OCF Margin % for the quarter that ended in Dec. 2025 was %.


OSE Immunotherapeutics OCF Yield % Explanation

Similar to Earnings Yield %, OCF Yield % is financial solvency ratio. A lower ratio suggests a less attractive investment, indicating that investors might not receive substantial returns in proportion to their investment. Conversely, a high operating cash flow yield signals that a company generates sufficient cash to comfortably meet its debts, obligations, and dividend payments, making it a promising investment choice.


OSE Immunotherapeutics OCF Yield % Related Terms


OSE Immunotherapeutics OCF Yield % Historical Data

* Premium members only.

The historical data trend for OSE Immunotherapeutics's OCF Yield % can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

OSE Immunotherapeutics OCF Yield % Chart

OSE Immunotherapeutics Annual Data
Trend Dec16 Dec17 Dec18 Dec19 Dec20 Dec21 Dec22 Dec23 Dec24 Dec25
OCF Yield %
Get a 7-Day Free Trial Premium Member Only Premium Member Only -5.22 -9.03 0.00 0.00 -15.32

OSE Immunotherapeutics Semi-Annual Data
Jun16 Dec16 Jun17 Dec17 Jun18 Dec18 Jun19 Dec19 Jun20 Dec20 Jun21 Dec21 Jun22 Dec22 Jun23 Dec23 Jun24 Dec24 Jun25 Dec25
OCF Yield % Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only 0.00 0.00 0.00 -17.07 -13.32

ORPOF vs VRTX, REGN, ALNY: OCF Yield % Comparison

For the Biotechnology subindustry, OSE Immunotherapeutics's OCF Yield %, along with its competitors' market caps and OCF Yield % data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


OSE Immunotherapeutics OCF Yield % vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, OSE Immunotherapeutics's OCF Yield % distribution charts can be found below:

* The bar in red indicates where OSE Immunotherapeutics's OCF Yield % falls into.


ORPOF
41GF Score
OSE Immunotherapeutics SA ORPOF
OCF Yield % is just one metric. See GF Score™, valuation, warning signs, and more.
View Full Analysis

OSE Immunotherapeutics OCF Yield % Calculation

OCF Yield % is a financial solvency ratio that compares the operating cash flow a company is expected to earn against its market value.

OSE Immunotherapeutics's OCF Yield % for the fiscal year that ended in Dec. 2025 is calculated as

OCF Yield %=Cash Flow from Operations / Market Cap
=-39.855 / 260.1068
=-15.32%

OSE Immunotherapeutics's annualized OCF Yield % for the quarter that ended in Dec. 2025 is calculated as

OCF Yield %=Cash Flow from Operations * Annualized Factor / Market Cap
=-17.329 * 2 / 260.1068
=-13.32%

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Frequently Asked Questions Learn more about OCF Yield % →
What does a OCF Yield % of -41.50 mean?
OSE Immunotherapeutics (ORPOF) has a OCF Yield % of -41.50 as of Jun. 27, 2026. OCF Yield is calculated as Cash Flow from Operations divided by Market Capitalization. View historical data on OSE Immunotherapeutics and its competitors. According to the industry distribution chart, OSE Immunotherapeutics ranks #1144 out of 1419 companies in the Biotechnology industry, placing it in the top 80.6%.
Is OSE Immunotherapeutics' OCF Yield % too high?
OSE Immunotherapeutics' current OCF Yield % is -41.50. Based on the distribution chart, OSE Immunotherapeutics ranks #1144 out of 1419 companies in the Biotechnology industry, which is in the bottom quartile relative to peers. Overall, OSE Immunotherapeutics has a GF Score™ of 41/100 and is considered Significantly Overvalued, reflecting its overall financial health beyond just this single metric.
How does OSE Immunotherapeutics' OCF Yield % compare to VRTX and REGN?
According to the Biotechnology industry distribution chart, OSE Immunotherapeutics ranks #1144 out of 1419 companies for OCF Yield %. This places OSE Immunotherapeutics in the lower half of its industry. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good OCF Yield % for a Biotechnology company?
A good OCF Yield % depends on the Biotechnology industry context. However, OCF Yield % should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high OCF Yield % mean?
A high OCF Yield % can signal that a stock is expensive relative to its fundamentals. OCF Yield is calculated as Cash Flow from Operations divided by Market Capitalization. View historical data on OSE Immunotherapeutics and its competitors. OSE Immunotherapeutics's current OCF Yield % is -41.50. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is OSE Immunotherapeutics stock overvalued right now?
Based on GuruFocus' analysis, OSE Immunotherapeutics (ORPOF) is currently considered Significantly Overvalued. The stock's GF Value™ is $3.36, compared to a current price of $4.43 — trading 31.8% above its estimated fair value. The current OCF Yield % is -41.50. OSE Immunotherapeutics' overall GF Score™ is 41/100 with 6 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is OCF Yield % calculated?
OCF Yield % is calculated from a company's financial statements. For OSE Immunotherapeutics (ORPOF), the current OCF Yield % is -41.50 as of Jun. 27, 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Is OSE Immunotherapeutics (ORPOF) Overvalued in 2026?

Based on GuruFocus' analysis, OSE Immunotherapeutics stock appears to be overvalued. The current stock price of $4.43 is trading 31.8% above its estimated GF Value™ of $3.36. GuruFocus considers OSE Immunotherapeutics to be Significantly Overvalued.

Key valuation signals for ORPOF:

  • OCF Yield %: -41.50
  • GF Value™: $3.36 vs. price of $4.43 (31.8% above fair value)
  • GF Score™: 41/100 with 6 warning signs

No single metric tells the full story. See the ORPOF stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.


OSE Immunotherapeutics Business Description

Address 22, Boulevard Benoni Goullin, Nantes, FRA, 44200
OSE Immunotherapeutics SA is a France-based biotechnology company focused on the development of immunotherapies for immune activation and regulation in the fields of immuno-oncology and autoimmune diseases. The product portfolio of the company comprises Tedopi, OSE-172, OSE-703, FR104 and OSE-127.
41GF Score

Get the complete analysis for ORPOF

OCF Yield % is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

$4.43
Price
$3.36
GF Value