D. Western Therapeutics Institute (TSE:4576) E10: 円0.00 (As of Dec. 2025)


TSE:4576 D. Western Therapeutics Institute Inc TSE:4576
47 GF Score
Price 円69.00
GF Value 円64.35
Valuation Fairly Valued
! 3 Warning Signs
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What is D. Western Therapeutics Institute E10?

D. Western Therapeutics Institute TSE:4576 47 E10 is 円0.00 as of Dec. 2025. GuruFocus rates TSE:4576 with a GF Score™ of 47/100 and a GF Value™ of 円64.35 (Fairly Valued). The stock has 3 warning signs investors should review.

E10 is a concept invented by Prof. Robert Shiller, who uses E10 for his Shiller P/E calculation. E10 is the average of the inflation adjusted earnings of a company over the past 10 years.

D. Western Therapeutics Institute's adjusted earnings per share data for the three months ended in Dec. 2025 was 円0.000. Add all the adjusted EPS for the past 10 years together and divide 10 will get our e10, which is 円0.00 for the trailing ten years ended in Dec. 2025.

Please click Growth Rate Calculation Example (GuruFocus) to see how GuruFocus calculates Wal-Mart Stores Inc (WMT)'s revenue growth rate. You can apply the same method to get the E10 growth rate using E10 data.

During the past 13 years, the highest 3-Year average E10 Growth Rate of D. Western Therapeutics Institute was 5.10% per year. The lowest was -1.50% per year. And the median was 1.80% per year.

As of today (2026-06-28), D. Western Therapeutics Institute's current stock price is 円69.00. D. Western Therapeutics Institute's E10 for the quarter that ended in Dec. 2025 was 円0.00. D. Western Therapeutics Institute's Shiller PE Ratio of today is .


D. Western Therapeutics Institute  (TSE:4576) E10 Explanation

If a company grows much fast than inflation, E10 may underestimate the company's earnings power. Shiller PE Ratio can seem to be too high even the actual P/E is low.

For the Shiller P/E, the earnings of the past 10 years are inflation-adjusted and averaged. The result is used for P/E calculation. Since it looks at the average over the last 10 years, the Shiller P/E is also called PE10.

The Shiller P/E was first used by professor Robert Shiller to measure the valuation of the overall market. The same calculation is applied here to individual companies.


Be Aware

Shiller PE Ratio works better for cyclical companies. It gives you a better idea on the company's real earnings power.


D. Western Therapeutics Institute E10 Related Terms


D. Western Therapeutics Institute E10 Historical Data

* Premium members only.

The historical data trend for D. Western Therapeutics Institute's E10 can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

D. Western Therapeutics Institute E10 Chart

D. Western Therapeutics Institute Annual Data
Trend Dec16 Dec17 Dec18 Dec19 Dec20 Dec21 Dec22 Dec23 Dec24 Dec25
E10
Get a 7-Day Free Trial Premium Member Only Premium Member Only -15.89 -16.39 -18.22 0.00 0.00

D. Western Therapeutics Institute Quarterly Data
Dec20 Mar21 Jun21 Sep21 Dec21 Mar22 Jun22 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Dec24 Mar25 Jun25 Dec25 Mar26
E10 Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only 0.00 -20.51 -20.68 0.00 0.00

TSE:4576 vs VRTX, REGN, ALNY: E10 Comparison

For the Biotechnology subindustry, D. Western Therapeutics Institute's Shiller PE Ratio, along with its competitors' market caps and Shiller PE Ratio data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


D. Western Therapeutics Institute Shiller PE Ratio vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, D. Western Therapeutics Institute's Shiller PE Ratio distribution charts can be found below:

* The bar in red indicates where D. Western Therapeutics Institute's Shiller PE Ratio falls into.


TSE:4576
47GF Score
D. Western Therapeutics Institute Inc TSE:4576
E10 is just one metric. See GF Score™, valuation, warning signs, and more.
View Full Analysis

D. Western Therapeutics Institute E10 Calculation

E10 is a concept invented by Prof. Robert Shiller, who uses E10 for his Shiller P/E calculation. When we calculate the today's Shiller P/E ratio of a stock, we use today's price divided by E10.

What is E10? How do we calculate E10?

E10 is the average of the inflation adjusted earnings of a company over the past 10 years. Let's use an example to explain.

If we want to calculate the E10 of Wal-Mart (WMT) for Dec. 31, 2010, we need to have the inflation data and the earnings from 2001 through 2010.

We adjusted the earnings of 2001 earnings data with the total inflation from 2001 through 2010 to the equivalent earnings in 2010. If the total inflation from 2001 to 2010 is 40%, and Wal-Mart earned $1 a share in 2001, then the 2001's equivalent earnings in 2010 is $1.4 a share. If Wal-Mart earns $1 again in 2002, and the total inflation from 2002 through 2010 is 35%, then the equivalent 2002 earnings in 2010 is $1.35. So on and so forth, you get the equivalent earnings of past 10 years. Then you add them together and divided the sum by 10 to get E10.

Please note that we use the CPI data of the country/region where the company is headquartered. If the CPI data for that country/region is not available, then we will use the CPI data of the United States as default.

For example, D. Western Therapeutics Institute's adjusted earnings per share data for the three months ended in Dec. 2025 was:

Adj_EPS= Earnings per Share (Diluted) /CPI of Dec. 2025 (Change)*Current CPI (Dec. 2025)
=0/113.0000*113.0000
=0.000

Current CPI (Dec. 2025) = 113.0000.

D. Western Therapeutics Institute Quarterly Data

per share eps CPI Adj_EPS
201509 -2.860 98.500 -3.281
201512 -3.350 98.100 -3.859
201603 -1.630 97.900 -1.881
201606 -3.100 98.100 -3.571
201609 -3.090 98.000 -3.563
201612 -2.640 98.400 -3.032
201703 -6.630 98.100 -7.637
201706 -44.350 98.500 -50.879
201709 -0.408 98.800 -0.467
201712 -8.750 99.400 -9.947
201803 -7.020 99.200 -7.997
201806 -6.890 99.200 -7.848
201809 -7.742 99.900 -8.757
201812 -6.862 99.700 -7.777
201903 5.810 99.700 6.585
201906 -0.660 99.800 -0.747
201909 -0.585 100.100 -0.660
201912 0.500 100.500 0.562
202003 -1.660 100.300 -1.870
202006 -2.030 99.900 -2.296
202009 -2.010 99.900 -2.274
202012 -4.460 99.300 -5.075
202103 -1.410 99.900 -1.595
202106 -1.420 99.500 -1.613
202109 -0.650 100.100 -0.734
202112 -1.604 100.100 -1.811
202203 -0.740 101.100 -0.827
202206 -3.020 101.800 -3.352
202209 -3.940 103.100 -4.318
202212 -6.800 104.100 -7.381
202303 -3.140 104.400 -3.399
202306 -4.750 105.200 -5.102
202309 -6.130 106.200 -6.523
202312 -11.540 106.800 -12.210
202403 -9.990 107.200 -10.531
202406 -6.160 108.200 -6.433
202412 0.000 110.700 0.000
202503 -3.410 111.100 -3.468
202506 -3.670 111.700 -3.713
202512 0.000 113.000 0.000

Add all the adjusted EPS together and divide 10 will get our e10.

Frequently Asked Questions Learn more about E10 →
What does a E10 of 円0.00 mean?
D. Western Therapeutics Institute (TSE:4576) has a E10 of 円0.00 as of Dec. 2025. E10 represents the company's inflation-adjusted earnings per share over a 10-year period. View historical data on D. Western Therapeutics Institute and its competitors.
Is D. Western Therapeutics Institute's E10 too high?
D. Western Therapeutics Institute's current E10 is 円0.00. Overall, D. Western Therapeutics Institute has a GF Score™ of 47/100 and is considered Fairly Valued, reflecting its overall financial health beyond just this single metric.
How does D. Western Therapeutics Institute's E10 compare to VRTX and REGN?
D. Western Therapeutics Institute's E10 of 円0.00 can be compared against companies in the Biotechnology industry. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good E10 for a Biotechnology company?
A good E10 depends on the Biotechnology industry context. However, E10 should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high E10 mean?
A high E10 can signal that a stock is expensive relative to its fundamentals. E10 represents the company's inflation-adjusted earnings per share over a 10-year period. View historical data on D. Western Therapeutics Institute and its competitors. D. Western Therapeutics Institute's current E10 is 円0.00. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is D. Western Therapeutics Institute stock overvalued right now?
Based on GuruFocus' analysis, D. Western Therapeutics Institute (TSE:4576) is currently considered Fairly Valued. The stock's GF Value™ is 円64.35, compared to a current price of 円69.00 — trading 7.2% above its estimated fair value. The current E10 is 円0.00. D. Western Therapeutics Institute's overall GF Score™ is 47/100 with 3 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is E10 calculated?
E10 is calculated from a company's financial statements. For D. Western Therapeutics Institute (TSE:4576), the current E10 is 円0.00 as of Dec. 2025. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Is D. Western Therapeutics Institute (TSE:4576) Overvalued in 2026?

Based on GuruFocus' analysis, D. Western Therapeutics Institute stock appears to be overvalued. The current stock price of 円69.00 is trading 7.2% above its estimated GF Value™ of 円64.35. GuruFocus considers D. Western Therapeutics Institute to be Fairly Valued.

Key valuation signals for TSE:4576:

  • E10: 円0.00
  • GF Value™: 円64.35 vs. price of 円69.00 (7.2% above fair value)
  • GF Score™: 47/100 with 3 warning signs

No single metric tells the full story. See the TSE:4576 stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.


D. Western Therapeutics Institute Business Description

Other Exchanges 6DW:Germany
Address 7th Floor, 18 KT Bulding, 1-18-11, Nishiki, Naka-ku, Aichi, Nagoyashi, JPN, 460-0003
D. Western Therapeutics Institute Inc is engaged in the research and development of pharmaceutical drugs in Japan. Its products include ophthalmic solution and agents for antiplatelet and anti-glaucoma.
47GF Score

Get the complete analysis for TSE:4576

E10 is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

円69.00
Price
円64.35
GF Value