D. Western Therapeutics Institute (TSE:4576) Gross Margin %: 0.00% (As of Dec. 2025)


TSE:4576 D. Western Therapeutics Institute Inc TSE:4576
45 GF Score
Price 円74.00
GF Value 円64.17
Valuation Modestly Overvalued
! 3 Warning Signs
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What is D. Western Therapeutics Institute Gross Margin %?

D. Western Therapeutics Institute TSE:4576 +1.37% 45 Gross Margin % is 0.00% as of Dec. 2025. GuruFocus rates TSE:4576 with a GF Score™ of 45/100 and a GF Value™ of 円64.17 (Modestly Overvalued). The stock has 3 warning signs investors should review. Among 735 Biotechnology companies, D. Western Therapeutics Institute ranks better than 86.67% on this metric.

Gross Margin % is calculated as gross profit divided by its revenue. D. Western Therapeutics Institute's Gross Profit for the three months ended in Dec. 2025 was 円0.00 Mil. D. Western Therapeutics Institute's Revenue for the three months ended in Dec. 2025 was 円0.00 Mil. Therefore, D. Western Therapeutics Institute's Gross Margin % for the quarter that ended in Dec. 2025 was 0.00%. If there's no value for Cost of Goods Sold, then Gross Margin % is not calculated.

Warning Sign:

D. Western Therapeutics Institute Inc gross margin has been in long-term decline. The average rate of decline per year is -1.3%.


The historical rank and industry rank for D. Western Therapeutics Institute's Gross Margin % or its related term are showing as below:

TSE:4576' s Gross Margin % Range Over the Past 10 Years
Min: 89.97   Med: 95.18   Max: 97.12
Current: 91.95


During the past 13 years, the highest Gross Margin % of D. Western Therapeutics Institute was 97.12%. The lowest was 89.97%. And the median was 95.18%.

TSE:4576's Gross Margin % is ranked better than
86.67% of 735 companies
in the Biotechnology industry
Industry Median: 60.9 vs TSE:4576: 91.95

D. Western Therapeutics Institute had a gross margin of N/A% for the quarter that ended in Dec. 2025 => No sustainable competitive advantage

The 5-Year average Growth Rate of Gross Margin for D. Western Therapeutics Institute was -1.30% per year.


D. Western Therapeutics Institute  (TSE:4576) Gross Margin % Explanation

Warren Buffett believes that firms with excellent long term economics tend to have consistently higher margins.

Durable competitive advantage creates a high Gross Margin % because of the freedom to price in excess of cost. Companies can be categorized by their Gross Margin %

1. Greater than 40% = Durable competitive advantage
2. Less than 40% = Competition eroding margins
3. Less than 20% = no sustainable competitive advantage
Consistency of Gross Margin is key

D. Western Therapeutics Institute had a gross margin of N/A% for the quarter that ended in Dec. 2025 => No sustainable competitive advantage


Be Aware

If a company loses its competitive advantages, usually its gross margin declines well before its sales declines. Watching Gross Margin % and Operating Margin % closely helps avoid value trap situations.


D. Western Therapeutics Institute Gross Margin % Related Terms


D. Western Therapeutics Institute Gross Margin % Historical Data

* Premium members only.

The historical data trend for D. Western Therapeutics Institute's Gross Margin % can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

D. Western Therapeutics Institute Gross Margin % Chart

D. Western Therapeutics Institute Annual Data
Trend Dec16 Dec17 Dec18 Dec19 Dec20 Dec21 Dec22 Dec23 Dec24 Dec25
Gross Margin %
Get a 7-Day Free Trial Premium Member Only Premium Member Only 95.15 93.85 91.44 90.07 89.97

D. Western Therapeutics Institute Quarterly Data
Dec20 Mar21 Jun21 Sep21 Dec21 Mar22 Jun22 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Dec24 Mar25 Jun25 Dec25 Mar26
Gross Margin % Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only 0.00 89.56 90.36 0.00 0.00

TSE:4576 vs VRTX, REGN, ALNY: Gross Margin % Comparison

For the Biotechnology subindustry, D. Western Therapeutics Institute's Gross Margin %, along with its competitors' market caps and Gross Margin % data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


D. Western Therapeutics Institute Gross Margin % vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, D. Western Therapeutics Institute's Gross Margin % distribution charts can be found below:

* The bar in red indicates where D. Western Therapeutics Institute's Gross Margin % falls into.


TSE:4576
45GF Score
D. Western Therapeutics Institute Inc TSE:4576
Gross Margin % is just one metric. See GF Score™, valuation, warning signs, and more.
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D. Western Therapeutics Institute Gross Margin % Calculation

Gross Margin is the percentage of Gross Profit out of sales or Revenue. (Note that if there's no value for Cost of Goods Sold, then Gross Margin % is not calculated.)

D. Western Therapeutics Institute's Gross Margin for the fiscal year that ended in Dec. 2025 is calculated as

Gross Margin % (A: Dec. 2025 )=Gross Profit (A: Dec. 2025 ) / Revenue (A: Dec. 2025 )
=348.8 / 387.62
=(Revenue - Cost of Goods Sold) / Revenue
=(387.62 - 38.86) / 387.62
=89.97 %

D. Western Therapeutics Institute's Gross Margin for the quarter that ended in Dec. 2025 is calculated as


Gross Margin % (Q: Dec. 2025 )=Gross Profit (Q: Dec. 2025 ) / Revenue (Q: Dec. 2025 )
=0 / 0
=(Revenue - Cost of Goods Sold) / Revenue
=(0 - 0) / 0
=N/A %

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

A positive Gross Profit is only the first step for a company to make a net profit. The gross profit needs to be big enough to also cover related labor, equipment, rental, marketing/advertising, research and development and a lot of other costs in selling the products.

Frequently Asked Questions Learn more about Gross Margin % →
What does a Gross Margin % of 0.00% mean?
D. Western Therapeutics Institute (TSE:4576) has a Gross Margin % of 0.00% as of Dec. 2025. Gross margin is the ratio of total gross profit to net sales. View historical data on D. Western Therapeutics Institute and its competitors. Over the past decade, D. Western Therapeutics Institute's Gross Margin % has ranged from 89.97 to 97.12. According to the industry distribution chart, D. Western Therapeutics Institute ranks #98 out of 735 companies in the Biotechnology industry, placing it in the top 13.3%.
Is D. Western Therapeutics Institute's Gross Margin % too high?
D. Western Therapeutics Institute's current Gross Margin % is 0.00%. Over the past 10 years, this metric has ranged from a low of 89.97 to a high of 97.12. Based on the distribution chart, D. Western Therapeutics Institute ranks #98 out of 735 companies in the Biotechnology industry, which is in the top quartile — a strong position relative to peers. Overall, D. Western Therapeutics Institute has a GF Score™ of 45/100 and is considered Modestly Overvalued, reflecting its overall financial health beyond just this single metric.
How does D. Western Therapeutics Institute's Gross Margin % compare to VRTX and REGN?
According to the Biotechnology industry distribution chart, D. Western Therapeutics Institute ranks #98 out of 735 companies for Gross Margin %. This places D. Western Therapeutics Institute in the top 13% of its industry — outperforming the majority of peers. The industry median Gross Margin % is 60.90. Historically, D. Western Therapeutics Institute's own Gross Margin % has ranged from 89.97 to 97.12 over the past decade. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good Gross Margin % for a Biotechnology company?
The median Gross Margin % among Biotechnology companies is 60.90, based on 735 companies in the industry. Companies in the top quartile (top 25%) have a Gross Margin % significantly above this median, while those in the bottom quartile fall well below. However, Gross Margin % should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high Gross Margin % mean?
A high Gross Margin % can signal that a stock is expensive relative to its fundamentals. Gross margin is the ratio of total gross profit to net sales. View historical data on D. Western Therapeutics Institute and its competitors. For the Biotechnology industry, the median Gross Margin % is 60.90 — values significantly above this may indicate overvaluation, while values below may suggest a bargain or underlying issues. D. Western Therapeutics Institute's current Gross Margin % is 0.00%. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is D. Western Therapeutics Institute stock overvalued right now?
Based on GuruFocus' analysis, D. Western Therapeutics Institute (TSE:4576) is currently considered Modestly Overvalued. The stock's GF Value™ is 円64.17, compared to a current price of 円74.00 — trading 15.3% above its estimated fair value. The current Gross Margin % is 0.00%. D. Western Therapeutics Institute's overall GF Score™ is 45/100 with 3 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is Gross Margin % calculated?
Gross Margin % is calculated from a company's financial statements. For D. Western Therapeutics Institute (TSE:4576), the current Gross Margin % is 0.00% as of Dec. 2025. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Is D. Western Therapeutics Institute (TSE:4576) Overvalued in 2026?

Based on GuruFocus' analysis, D. Western Therapeutics Institute stock appears to be overvalued. The current stock price of 円74.00 is trading 15.3% above its estimated GF Value™ of 円64.17. GuruFocus considers D. Western Therapeutics Institute to be Modestly Overvalued.

Key valuation signals for TSE:4576:

  • Gross Margin %: 0.00%
  • GF Value™: 円64.17 vs. price of 円74.00 (15.3% above fair value)
  • GF Score™: 45/100 with 3 warning signs

No single metric tells the full story. See the TSE:4576 stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.


D. Western Therapeutics Institute Business Description

Other Exchanges 6DW:Germany
Address 7th Floor, 18 KT Bulding, 1-18-11, Nishiki, Naka-ku, Aichi, Nagoyashi, JPN, 460-0003
D. Western Therapeutics Institute Inc is engaged in the research and development of pharmaceutical drugs in Japan. Its products include ophthalmic solution and agents for antiplatelet and anti-glaucoma.
45GF Score

Get the complete analysis for TSE:4576

Gross Margin % is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

円74.00
Price
円64.17
GF Value