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EV-to-EBITDA is calculated as enterprise value divided by its EBITDA. As of today, D. Western Therapeutics Institute's enterprise value is 円4,065.8 Mil.
D. Western Therapeutics Institute's EBITDA for the trailing twelve months (TTM) ended in Jun. 2026 was 円-593.5 Mil. Therefore, D. Western Therapeutics Institute's EV-to-EBITDA for today is -6.85.
The historical rank and industry rank for D. Western Therapeutics Institute's EV-to-EBITDA or its related term are showing as below:
TSE:4576'
s EV-to-EBITDA Range Over the Past 10 Years
Min: -176.06 Med: -13.98 Max: 138.64
Current: -6.85
During the past 13 years, the highest EV-to-EBITDA of D. Western Therapeutics Institute was 138.64. The lowest was -176.06. And the median was -13.98.
TSE:4576's EV-to-EBITDA is ranked worse than 100% of 407
companies
in the Biotechnology industry
Industry Median: 14.17
vs TSE:4576: -6.85
EV-to-EBITDA is a valuation multiple used in finance and investment to measure the value of a company. This important multiple is often used in conjunction with, or as an alternative to, the PE Ratio to determine the fair market value of a company.
D. Western Therapeutics Institute (TSE:4576) EV-to-EBITDA Explanation
EV-to-EBITDA is a valuation multiple used in finance and investment to measure the value of a company. This important multiple is often used in conjunction with, or as an alternative to, the PE Ratio (TTM) to determine the fair market value of a company.
D. Western Therapeutics Institute's PE Ratio (TTM) for today is calculated as:
D. Western Therapeutics Institute's share price for today is 円88.00.
D. Western Therapeutics Institute's Earnings per Share (Diluted) for the trailing twelve months (TTM) ended in Jun. 2026 adds up the quarterly data reported by the company within the most recent 12 months, which was 円-12.920.
* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD. * For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.
Study has found that the companies with the lowest EV-to-EBITDA outperforms companies measured as cheap by other ratios such as PE Ratio (TTM).
* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD. * For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.
D. Western Therapeutics Institute EV-to-EBITDA Chart
TSE:4576 vs VRTX, REGN, RVMD: EV-to-EBITDA Comparison
For the Biotechnology subindustry, D. Western Therapeutics Institute's EV-to-EBITDA, along with its competitors' market caps and EV-to-EBITDA data, can be viewed below:
* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.
D. Western Therapeutics Institute EV-to-EBITDA vs Biotechnology Industry
For the Biotechnology industry and Healthcare sector, D. Western Therapeutics Institute's EV-to-EBITDA distribution charts can be found below:
* The bar in red indicates where D. Western Therapeutics Institute's EV-to-EBITDA falls into.
D. Western Therapeutics Institute's current Enterprise Value is 円4,065.8 Mil.
D. Western Therapeutics Institute's EBITDA for the trailing twelve months (TTM) ended in Jun. 2026 adds up the quarterly data reported by the company within the most recent 12 months, which was 円-593.5 Mil.
* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD. * For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.
D. Western Therapeutics Institute (TSE:4576) has a EV-to-EBITDA of -6.85 as of Aug. 23, 2026. EV to EBITDA ratio is the company's enterprise value divided by earnings before interest, taxes, depreciation and amortization. View historical data on D. Western Therapeutics Institute. According to the industry distribution chart, D. Western Therapeutics Institute ranks #999999 out of 407 companies in the Biotechnology industry.
Is D. Western Therapeutics Institute's EV-to-EBITDA too high?
D. Western Therapeutics Institute's current EV-to-EBITDA is -6.85. Based on the distribution chart, D. Western Therapeutics Institute ranks #999999 out of 407 companies in the Biotechnology industry, which is in the bottom quartile relative to peers. Overall, D. Western Therapeutics Institute has a GF Score™ of 35/100 and is considered Significantly Overvalued, reflecting its overall financial health beyond just this single metric.
How does D. Western Therapeutics Institute's EV-to-EBITDA compare to VRTX and REGN?
According to the Biotechnology industry distribution chart, D. Western Therapeutics Institute ranks #999999 out of 407 companies for EV-to-EBITDA. This places D. Western Therapeutics Institute in the lower half of its industry. The industry median EV-to-EBITDA is 14.17. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good EV-to-EBITDA for a Biotechnology company?
The median EV-to-EBITDA among Biotechnology companies is 14.17, based on 407 companies in the industry. Companies in the top quartile (top 25%) have a EV-to-EBITDA significantly above this median, while those in the bottom quartile fall well below. However, EV-to-EBITDA should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high EV-to-EBITDA mean?
A high EV-to-EBITDA can signal that a stock is expensive relative to its fundamentals. EV to EBITDA ratio is the company's enterprise value divided by earnings before interest, taxes, depreciation and amortization. View historical data on D. Western Therapeutics Institute. For the Biotechnology industry, the median EV-to-EBITDA is 14.17 — values significantly above this may indicate overvaluation, while values below may suggest a bargain or underlying issues. D. Western Therapeutics Institute's current EV-to-EBITDA is -6.85. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is D. Western Therapeutics Institute stock overvalued right now?
Based on GuruFocus' analysis, D. Western Therapeutics Institute (TSE:4576) is currently considered Significantly Overvalued. The stock's GF Value™ is 円44.69, compared to a current price of 円88.00 — trading 96.9% above its estimated fair value. The current EV-to-EBITDA is -6.85. D. Western Therapeutics Institute's overall GF Score™ is 35/100 with 4 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is EV-to-EBITDA calculated?
EV-to-EBITDA is calculated from a company's financial statements. For D. Western Therapeutics Institute (TSE:4576), the current EV-to-EBITDA is -6.85 as of Aug. 23, 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.
Is D. Western Therapeutics Institute (TSE:4576) Overvalued in 2026?
Based on GuruFocus' analysis, D. Western Therapeutics Institute stock appears to be overvalued.
The current stock price of 円88.00 is trading 96.9% above its estimated GF Value™ of 円44.69.
GuruFocus considers D. Western Therapeutics Institute to be Significantly Overvalued.
Key valuation signals for TSE:4576:
EV-to-EBITDA: -6.85
GF Value™: 円44.69 vs. price of 円88.00 (96.9% above fair value)
No single metric tells the full story. See the TSE:4576 stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.
D. Western Therapeutics Institute Inc is engaged in the research and development of pharmaceutical drugs in Japan. Its products include ophthalmic solution and agents for antiplatelet and anti-glaucoma.
35GF Score
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