Focused on building reliable datasets, financial models, and research tools for value-minded investors. Committed to turning complex data into practical guidance for value-investing and long-term wealth.
Dr. Charlie Tian is the founder and CEO of GuruFocus.com, a leading global investment research platform established in 2004. With a Ph.D. in physics, Dr. Tian transitioned from science to finance, applying a data-driven, disciplined approach to value investing.
D. Western Therapeutics InstituteTSE:4576 -3.70%45 Net Debt Paydown Yield % is 9.75% as of Jul. 19, 2026, which is 1974% above its 10-year median of 0.47. GuruFocus rates TSE:4576 with a GF Score™ of 45/100 and a GF Value™ of 円68.61 (Modestly Overvalued). The stock has 3 warning signs investors should review. Among 1,163 Biotechnology companies, D. Western Therapeutics Institute ranks better than 91.32% on this metric.
Net Debt Paydown Yield % is a metric that evaluates the total amount of debt a company has paid in relation to its market capitalization. It is a measure of a company's willingness and ability to reduce its debt.
As of today, D. Western Therapeutics Institute's Net Debt Paydown Yield % was 9.75%.
D. Western Therapeutics Institute (TSE:4576) Net Debt Paydown Yield % Explanation
Net Debt Paydown Yield % is the change in average of four quarters of company's total debt over a company's market cap. Assuming the total value of a company remains that same, shareholder value is increased as debt is reduced. In other words, it is a measure of the willingness and ability of a firm's management to pay down debt. Companies that have high debt paydown yields indicate that they are more aggressive with paying down debt.
In the calculation of Net Debt Paydown Yield %, we use the reductions of TTM average total debt one-year-ago and TTM average total debt at present, divided by its Market Cap.
* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD. * For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.
D. Western Therapeutics Institute Net Debt Paydown Yield % Chart
TSE:4576 vs VRTX, REGN, ALNY: Net Debt Paydown Yield % Comparison
For the Biotechnology subindustry, D. Western Therapeutics Institute's Net Debt Paydown Yield %, along with its competitors' market caps and Net Debt Paydown Yield % data, can be viewed below:
* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.
D. Western Therapeutics Institute Net Debt Paydown Yield % vs Biotechnology Industry
For the Biotechnology industry and Healthcare sector, D. Western Therapeutics Institute's Net Debt Paydown Yield % distribution charts can be found below:
* The bar in red indicates where D. Western Therapeutics Institute's Net Debt Paydown Yield % falls into.
* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD. * For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.
* All the data are calculated by TTM values. Note that if a companies is traded in several exchanges, then we calculate the company level data for Net Debt Paydown Yield % using the primary share class stock data. The calculation result in definition page is for demonstration purpose only, and it's showing the share class level data. Therefore, the numbers in the calculation may differ from elsewhere if the stock is not a primary share.
What does a Net Debt Paydown Yield % of 9.75% mean?
D. Western Therapeutics Institute (TSE:4576) has a Net Debt Paydown Yield % of 9.75% as of Jul. 19, 2026. Net Debt Paydown Yield is a metric that evaluates the total amount of debt a company has paid in relation to its market capitalization. This metric provides insight into a company's willingness and ability to reduce its debt using free cash flow. View historical data on D. Western Therapeutics Institute and its competitors. This is 1974% above median its historical median of 0.47. According to the industry distribution chart, D. Western Therapeutics Institute ranks #101 out of 1163 companies in the Biotechnology industry, placing it in the top 8.7%.
Is D. Western Therapeutics Institute's Net Debt Paydown Yield % too high?
D. Western Therapeutics Institute's current Net Debt Paydown Yield % of 9.75% is 1974% above median its 10-year median of 0.47. The Biotechnology industry median Net Debt Paydown Yield % is 0.03. D. Western Therapeutics Institute's value of 9.75% is 32400% above this industry median. Based on the distribution chart, D. Western Therapeutics Institute ranks #101 out of 1163 companies in the Biotechnology industry, which is in the top quartile — a strong position relative to peers. Overall, D. Western Therapeutics Institute has a GF Score™ of 45/100 and is considered Modestly Overvalued, reflecting its overall financial health beyond just this single metric.
How does D. Western Therapeutics Institute's Net Debt Paydown Yield % compare to VRTX and REGN?
According to the Biotechnology industry distribution chart, D. Western Therapeutics Institute ranks #101 out of 1163 companies for Net Debt Paydown Yield %. This places D. Western Therapeutics Institute in the top 9% of its industry — outperforming the majority of peers. The industry median Net Debt Paydown Yield % is 0.03. D. Western Therapeutics Institute's value of 9.75% is 32400% above this benchmark. While the company's 10-year median is 0.47 vs. the industry median of 0.03, D. Western Therapeutics Institute has consistently been above the industry average. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good Net Debt Paydown Yield % for a Biotechnology company?
The median Net Debt Paydown Yield % among Biotechnology companies is 0.03, based on 1,163 companies in the industry. Companies in the top quartile (top 25%) have a Net Debt Paydown Yield % significantly above this median, while those in the bottom quartile fall well below. However, Net Debt Paydown Yield % should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. D. Western Therapeutics Institute's current Net Debt Paydown Yield % of 9.75% is 32400% above the industry median. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high Net Debt Paydown Yield % mean?
A high Net Debt Paydown Yield % can signal that a stock is expensive relative to its fundamentals. Net Debt Paydown Yield is a metric that evaluates the total amount of debt a company has paid in relation to its market capitalization. This metric provides insight into a company's willingness and ability to reduce its debt using free cash flow. View historical data on D. Western Therapeutics Institute and its competitors. For the Biotechnology industry, the median Net Debt Paydown Yield % is 0.03 — values significantly above this may indicate overvaluation, while values below may suggest a bargain or underlying issues. D. Western Therapeutics Institute's current Net Debt Paydown Yield % is 9.75%, which is 1974% above median its own 10-year median of 0.47. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is D. Western Therapeutics Institute stock overvalued right now?
Based on GuruFocus' analysis, D. Western Therapeutics Institute (TSE:4576) is currently considered Modestly Overvalued. The stock's GF Value™ is 円68.61, compared to a current price of 円78.00 — trading 13.7% above its estimated fair value. The current Net Debt Paydown Yield % is 9.75%, which is 1974% above median its 10-year median of 0.47 and 32400% above the Biotechnology industry median of 0.03. D. Western Therapeutics Institute's overall GF Score™ is 45/100 with 3 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is Net Debt Paydown Yield % calculated?
Net Debt Paydown Yield % is calculated from a company's financial statements. For D. Western Therapeutics Institute (TSE:4576), the current Net Debt Paydown Yield % is 9.75% as of Jul. 19, 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.
Is D. Western Therapeutics Institute (TSE:4576) Overvalued in 2026?
Based on GuruFocus' analysis, D. Western Therapeutics Institute stock appears to be overvalued.
The current stock price of 円78.00 is trading 13.7% above its estimated GF Value™ of 円68.61.
GuruFocus considers D. Western Therapeutics Institute to be Modestly Overvalued.
Key valuation signals for TSE:4576:
Net Debt Paydown Yield %: 9.75% (1974% above median its 10-year median of 0.47)
GF Value™: 円68.61 vs. price of 円78.00 (13.7% above fair value)
Industry Position: 32400% above the Biotechnology median (#101 of 1163)
No single metric tells the full story. See the TSE:4576 stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.
D. Western Therapeutics Institute Business Description
D. Western Therapeutics Institute Inc is engaged in the research and development of pharmaceutical drugs in Japan. Its products include ophthalmic solution and agents for antiplatelet and anti-glaucoma.
45GF Score
Get the complete analysis for TSE:4576
Net Debt Paydown Yield % is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.
Quick Browse
Personalize
Premium Gurus 
Create New Portfolio
TSE:4576 has been successfully added to your 
