D. Western Therapeutics Institute (TSE:4576) Operating Margin %: 0.00% (As of Dec. 2025)


TSE:4576 D. Western Therapeutics Institute Inc TSE:4576
51 GF Score
Price 円69.00
GF Value 円64.35
Valuation Fairly Valued
! 3 Warning Signs
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What is D. Western Therapeutics Institute Operating Margin %?

D. Western Therapeutics Institute TSE:4576 -1.43% 51 Operating Margin % is 0.00% as of Dec. 2025. GuruFocus rates TSE:4576 with a GF Score™ of 51/100 and a GF Value™ of 円64.35 (Fairly Valued). The stock has 3 warning signs investors should review. Among 944 Biotechnology companies, D. Western Therapeutics Institute ranks worse than 66.84% on this metric.

Operating Margin % is calculated as Operating Income divided by its Revenue. D. Western Therapeutics Institute's Operating Income for the three months ended in Dec. 2025 was 円0.00 Mil. D. Western Therapeutics Institute's Revenue for the three months ended in Dec. 2025 was 円0.00 Mil. Therefore, D. Western Therapeutics Institute's Operating Margin % for the quarter that ended in Dec. 2025 was 0.00%.

Warning Sign:

D. Western Therapeutics Institute Inc operating margin has been in a 5-year decline. The average rate of decline per year is -34.1%.

The historical rank and industry rank for D. Western Therapeutics Institute's Operating Margin % or its related term are showing as below:

TSE:4576' s Operating Margin % Range Over the Past 10 Years
Min: -364.95   Med: -173.17   Max: 20.21
Current: -364.95


TSE:4576's Operating Margin % is ranked worse than
66.84% of 944 companies
in the Biotechnology industry
Industry Median: -86.83 vs TSE:4576: -364.95

D. Western Therapeutics Institute's 5-Year Average Operating Margin % Growth Rate was -34.10% per year.

D. Western Therapeutics Institute's Operating Income for the three months ended in Dec. 2025 was 円0.00 Mil. Its Operating Income for the trailing twelve months (TTM) ended in Dec. 2025 was 円-334.27 Mil.


D. Western Therapeutics Institute  (TSE:4576) Operating Margin % Explanation

Just like Gross Margin %, it is important to see a company maintains its operating margin over time. Among the same industry, a company with higher operating margin is more efficient in its operation. It is also more stable during industry slowdown or recessions. Peter Lynch prefers those with higher margins than those with lower margins.


Be Aware

Operating Margin % can be manipulated by adjusting the rate of depreciation, depletion and amortization (DDA).

If a company is facing competition, its Operating Margin % may decline. Often the Operating Margin % declines well before the company's Revenue or even profit decline. Therefore, Operating Margin % is a very important indicator of whether the company is facing problems.

For instance, by 2012, Nokia (NOK)'s problems were well known and its stock had lost more than 90% of its market value since 2007. But Nokia’s Operating Margin % had already been in decline since 2002, although its Earnings per Share (Diluted) were still rising. Investors who paid attention to Operating Margin % would have avoided this huge loss. The same can be said for Research-in-Motion (RIMM).

Therefore, Operating Margin % is a very important screening filter for GuruFocus. GuruFocus's Buffett-Munger screener requires that the profit margin is either consistent or expanding. The Model Portfolio of the Buffett-Munger screener has outperformed the market every year since inception in 2009.


D. Western Therapeutics Institute Operating Margin % Related Terms


D. Western Therapeutics Institute Operating Margin % Historical Data

* Premium members only.

The historical data trend for D. Western Therapeutics Institute's Operating Margin % can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

D. Western Therapeutics Institute Operating Margin % Chart

D. Western Therapeutics Institute Annual Data
Trend Dec16 Dec17 Dec18 Dec19 Dec20 Dec21 Dec22 Dec23 Dec24 Dec25
Operating Margin %
Get a 7-Day Free Trial Premium Member Only Premium Member Only -41.42 -68.27 -186.42 -256.50 -159.92

D. Western Therapeutics Institute Quarterly Data
Dec20 Mar21 Jun21 Sep21 Dec21 Mar22 Jun22 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Dec24 Mar25 Jun25 Dec25 Mar26
Operating Margin % Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only 0.00 -146.76 -218.38 0.00 -1,106.69

TSE:4576 vs VRTX, REGN, ALNY: Operating Margin % Comparison

For the Biotechnology subindustry, D. Western Therapeutics Institute's Operating Margin %, along with its competitors' market caps and Operating Margin % data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


D. Western Therapeutics Institute Operating Margin % vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, D. Western Therapeutics Institute's Operating Margin % distribution charts can be found below:

* The bar in red indicates where D. Western Therapeutics Institute's Operating Margin % falls into.


TSE:4576
51GF Score
D. Western Therapeutics Institute Inc TSE:4576
Operating Margin % is just one metric. See GF Score™, valuation, warning signs, and more.
View Full Analysis

D. Western Therapeutics Institute Operating Margin % Calculation

Operating Margin % - also known as operating income margin, operating profit margin and return on sales (ROS) - is the ratio of Operating Income divided by net sales or Revenue, usually presented in percent.

D. Western Therapeutics Institute's Operating Margin % for the fiscal year that ended in Dec. 2025 is calculated as

Operating Margin %=Operating Income (A: Dec. 2025 ) / Revenue (A: Dec. 2025 )
=-619.87 / 387.62
=-159.92 %

D. Western Therapeutics Institute's Operating Margin % for the quarter that ended in Dec. 2025 is calculated as

Operating Margin %=Operating Income (Q: Dec. 2025 ) / Revenue (Q: Dec. 2025 )
=0 / 0
= %

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Frequently Asked Questions Learn more about Operating Margin % →
What does a Operating Margin % of 0.00% mean?
D. Western Therapeutics Institute (TSE:4576) has a Operating Margin % of 0.00% as of Dec. 2025. Operating margin is the ratio of total operating income to net sales. View historical data on D. Western Therapeutics Institute and its competitors. According to the industry distribution chart, D. Western Therapeutics Institute ranks #631 out of 944 companies in the Biotechnology industry, placing it in the top 66.8%.
Is D. Western Therapeutics Institute's Operating Margin % too high?
D. Western Therapeutics Institute's current Operating Margin % is 0.00%. Based on the distribution chart, D. Western Therapeutics Institute ranks #631 out of 944 companies in the Biotechnology industry, which is below the industry midpoint. Overall, D. Western Therapeutics Institute has a GF Score™ of 51/100 and is considered Fairly Valued, reflecting its overall financial health beyond just this single metric.
How does D. Western Therapeutics Institute's Operating Margin % compare to VRTX and REGN?
According to the Biotechnology industry distribution chart, D. Western Therapeutics Institute ranks #631 out of 944 companies for Operating Margin %. This places D. Western Therapeutics Institute in the lower half of its industry. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good Operating Margin % for a Biotechnology company?
A good Operating Margin % depends on the Biotechnology industry context. However, Operating Margin % should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high Operating Margin % mean?
A high Operating Margin % can signal that a stock is expensive relative to its fundamentals. Operating margin is the ratio of total operating income to net sales. View historical data on D. Western Therapeutics Institute and its competitors. D. Western Therapeutics Institute's current Operating Margin % is 0.00%. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is D. Western Therapeutics Institute stock overvalued right now?
Based on GuruFocus' analysis, D. Western Therapeutics Institute (TSE:4576) is currently considered Fairly Valued. The stock's GF Value™ is 円64.35, compared to a current price of 円69.00 — trading 7.2% above its estimated fair value. The current Operating Margin % is 0.00%. D. Western Therapeutics Institute's overall GF Score™ is 51/100 with 3 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is Operating Margin % calculated?
Operating Margin % is calculated from a company's financial statements. For D. Western Therapeutics Institute (TSE:4576), the current Operating Margin % is 0.00% as of Dec. 2025. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Is D. Western Therapeutics Institute (TSE:4576) Overvalued in 2026?

Based on GuruFocus' analysis, D. Western Therapeutics Institute stock appears to be overvalued. The current stock price of 円69.00 is trading 7.2% above its estimated GF Value™ of 円64.35. GuruFocus considers D. Western Therapeutics Institute to be Fairly Valued.

Key valuation signals for TSE:4576:

  • Operating Margin %: 0.00%
  • GF Value™: 円64.35 vs. price of 円69.00 (7.2% above fair value)
  • GF Score™: 51/100 with 3 warning signs

No single metric tells the full story. See the TSE:4576 stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.


D. Western Therapeutics Institute Business Description

Other Exchanges 6DW:Germany
Address 7th Floor, 18 KT Bulding, 1-18-11, Nishiki, Naka-ku, Aichi, Nagoyashi, JPN, 460-0003
D. Western Therapeutics Institute Inc is engaged in the research and development of pharmaceutical drugs in Japan. Its products include ophthalmic solution and agents for antiplatelet and anti-glaucoma.
51GF Score

Get the complete analysis for TSE:4576

Operating Margin % is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

円69.00
Price
円64.35
GF Value