TLSA (Tiziana Life Sciences) EBIT: $-18.41 Mil (TTM As of Dec. 2025)

What is Tiziana Life Sciences EBIT?

Tiziana Life Sciences TLSA +4.42% 30 EBIT is $-18.41 Mil as of Dec. 2025. GuruFocus rates TLSA with a GF Score™ of 30/100. The stock has 2 warning signs investors should review.

Tiziana Life Sciences's earnings before interest and taxes (EBIT) for the six months ended in Dec. 2025 was $-9.23 Mil. Its earnings before interest and taxes (EBIT) for the trailing twelve months (TTM) ended in Dec. 2025 was $-18.41 Mil.

EBIT or Operating Income is linked to Return on Capital for both regular definition and Joel Greenblatt's definition. Tiziana Life Sciences's annualized ROC % for the quarter that ended in Dec. 2025 was -621.46%. Tiziana Life Sciences's annualized ROC (Joel Greenblatt) % for the quarter that ended in Dec. 2025 was -5,686.90%.

EBIT is also linked to Joel Greenblatt's definition of earnings yield. Tiziana Life Sciences's Earnings Yield (Joel Greenblatt) % for the quarter that ended in Dec. 2025 was -12.40%.

Tiziana Life Sciences (NAS:TLSA) EBIT Explanation

1. EBIT or Operating Income is linked to Return on Capital for both regular definition and Joel Greenblatt's definition.

Tiziana Life Sciences's annualized ROC % for the quarter that ended in Dec. 2025 is calculated as:

	ROC % (Q: Dec. 2025 )
=	NOPAT	/	Average Invested Capital
=	Operating Income * ( 1 - Tax Rate % )	/	( (Invested Capital (Q: Jun. 2025 )	+	Invested Capital (Q: Dec. 2025 ))	/ count )
=	-23.892 * ( 1 - 0% )	/	( (3.997	+	3.692)	/ 2 )
=	-23.892	/	3.8445
=	-621.46 %

where

	Invested Capital		(Q: Jun. 2025 )
=	Total Assets	-	Accounts Payable & Accrued Expense	-	Excess Cash
=	Total Assets	-	Accounts Payable & Accrued Expense	-	( Cash, Cash Equivalents, Marketable Securities	-	max(0, Total Current Liabilities	-	Total Current Assets	+	Cash, Cash Equivalents, Marketable Securities	))
=	16.597	-	7.281	-	( 7.251	-	max(0, 7.397	-	12.716	+	7.251	))
=	3.997

	Invested Capital		(Q: Dec. 2025 )
=	Total Assets	-	Accounts Payable & Accrued Expense	-	Excess Cash
=	Total Assets	-	Accounts Payable & Accrued Expense	-	( Cash, Cash Equivalents, Marketable Securities	-	max(0, Total Current Liabilities	-	Total Current Assets	+	Cash, Cash Equivalents, Marketable Securities	))
=	11.495	-	10.46	-	( 4.01	-	max(0, 11.209	-	8.552	+	4.01	))
=	3.692

Note: The Operating Income data used here is two times the semi-annual (Dec. 2025) data.

2. Joel Greenblatt's definition of Return on Capital:

Tiziana Life Sciences's annualized ROC (Joel Greenblatt) % for the quarter that ended in Dec. 2025 is calculated as:

	ROC (Joel Greenblatt) %		(Q: Dec. 2025 )
=	EBIT	/	Average of (Net fixed Assets	+	Net Working Capital)
=	EBIT	/	Average of (Property, Plant and Equipment	+	Net Working Capital)
			Q: Jun. 2025		Q: Dec. 2025
=	EBIT	/	( ( (Property, Plant and Equipment + Net Working Capital)	+	(Property, Plant and Equipment + Net Working Capital) )	/	count )
=	-18.454	/	( ( (0.15 + max(-7.29, 0))	+	(0.499 + max(-10.702, 0)) )	/	2 )
=	-18.454	/	( ( 0.15	+	0.499 )	/	2 )
=	-18.454	/	0.3245
=	-5,686.90 %

where Working Capital is:

	Working Capital		(Q: Jun. 2025 )
=	(Accounts Receivable	+	Total Inventories	+	Other Current Assets)	-	(Accounts Payable & Accrued Expense	+	Defer. Rev.	+	Other Current Liabilities)
=	(0	+	0	+	-1.7763568394003E-15)	-	(7.281	+	0	+	0.0090000000000003)
=	-7.29

	Working Capital		(Q: Dec. 2025 )
=	(Accounts Receivable	+	Total Inventories	+	Other Current Assets)	-	(Accounts Payable & Accrued Expense	+	Defer. Rev.	+	Other Current Liabilities)
=	(0	+	0	+	0.285)	-	(10.46	+	0.53	+	-0.0030000000000001)
=	-10.702

When net working capital is negative, 0 is used.

Note: The EBIT data used here is two times the semi-annual (Dec. 2025) EBIT data.

3. It is also linked to Joel Greenblatt's definition of Earnings Yield:

Tiziana Life Sciences's Earnings Yield (Joel Greenblatt) % for today is calculated as:

Earnings Yield (Joel Greenblatt) %	=	EBIT (TTM)	/	Enterprise Value (Q: Dec. 2025 )
	=	-18.413	/	148.521
	=	-12.40 %

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Tiziana Life Sciences EBIT Related Terms

Tiziana Life Sciences EBIT Historical Data

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The historical data trend for Tiziana Life Sciences's EBIT can be seen below:

Tiziana Life Sciences EBIT Chart

Tiziana Life Sciences Annual Data

Trend

Dec16

Dec17

Dec18

Dec19

Dec20

Dec21

Dec22

Dec23

Dec24

Dec25

EBIT

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-26.48

-15.36

-17.23

-16.74

-18.41

Tiziana Life Sciences Semi-Annual Data
	Jun16	Dec16	Jun17	Dec17	Jun18	Dec18	Jun19	Dec19	Jun20	Dec20	Jun21	Dec21	Jun22	Dec22	Jun23	Dec23	Jun24	Dec24	Jun25	Dec25
EBIT	Get a 7-Day Free Trial															-8.62	-6.51	-10.23	-9.19	-9.23

TLSA vs SPRB, MIST, TNYA: EBIT Comparison

For the Biotechnology subindustry, Tiziana Life Sciences's EV-to-EBIT, along with its competitors' market caps and EV-to-EBIT data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.

Tiziana Life Sciences EV-to-EBIT vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, Tiziana Life Sciences's EV-to-EBIT distribution charts can be found below:

* The bar in red indicates where Tiziana Life Sciences's EV-to-EBIT falls into.

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Tiziana Life Sciences Ltd TLSA

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Tiziana Life Sciences EBIT Calculation

EBIT, sometimes also called Earnings Before Interest and Taxes, is a measure of a firm's profit that includes all expenses except interest and income tax expenses. It is the difference between operating revenues and operating expenses. When a firm does not have non-operating income, then Operating Income is sometimes used as a synonym for EBIT and operating profit.

EBIT for the trailing twelve months (TTM) ended in Dec. 2025 adds up the semi-annually data reported by the company within the most recent 12 months, which was $-18.41 Mil.

Frequently Asked Questions Learn more about EBIT →

What does a EBIT of $-18.41 Mil mean?

Tiziana Life Sciences (TLSA) has a EBIT of $-18.41 Mil as of Dec. 2025. Earnings before interest and taxes is the difference between operating revenue and operating expenses. View historical data on Tiziana Life Sciences.

Is Tiziana Life Sciences' EBIT too high?

Tiziana Life Sciences' current EBIT is $-18.41 Mil. Overall, Tiziana Life Sciences has a GF Score™ of 30/100, reflecting its overall financial health beyond just this single metric.

How does Tiziana Life Sciences' EBIT compare to SPRB and MIST?

Tiziana Life Sciences' EBIT of $-18.41 Mil can be compared against companies in the Biotechnology industry. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.

What is a good EBIT for a Biotechnology company?

A good EBIT depends on the Biotechnology industry context. However, EBIT should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.

What does a high EBIT mean?

A high EBIT can signal that a stock is expensive relative to its fundamentals. Earnings before interest and taxes is the difference between operating revenue and operating expenses. View historical data on Tiziana Life Sciences. Tiziana Life Sciences's current EBIT is $-18.41 Mil. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.

Is Tiziana Life Sciences stock overvalued right now?

Tiziana Life Sciences (TLSA) has a current EBIT of $-18.41 Mil. The current EBIT is $-18.41 Mil. Tiziana Life Sciences' overall GF Score™ is 30/100 with 2 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.

How is EBIT calculated?

EBIT is calculated from a company's financial statements. For Tiziana Life Sciences (TLSA), the current EBIT is $-18.41 Mil as of Dec. 2025. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Tiziana Life Sciences Business Description

Industry Healthcare Biotechnology

Comparable Companies SPRB MIST TNYA NRXP CRBP PRQR HURA ACOG MENS ENLV VRTX REGN XBRU:UCB XBRU:ARGX XKRX:207940 ALNY ASX:CSL RVMD ONC MRNA

Other Exchanges 0RP:Germany

Address 2 Church Street, Clarendon House, Hamilton, BMU, HM 11

Website https://www.tizianalifesciences.com

Tiziana Life Sciences Ltd is a clinical-stage biotechnology company that specializes in developing transformative therapies for neurodegenerative and neuroinflammatory diseases. The company's clinical pipeline includes drug assets for Non-Active Secondary Progressive Multiple Sclerosis, Multiple System Atrophy, Alzheimer's, and Amyotrophic Lateral Sclerosis. The company's mission is to design and deliver next-generation immunotherapies for neurodegenerative and neuroinflammatory diseases. The company's main immunotherapeutic candidate, Foralumab (TZLS-401), is being developed for Non-Active Secondary Progressive Multiple Sclerosis, Alzheimer's, and other CNS indications.

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