TLSA (Tiziana Life Sciences) EBITDA per Share: $-0.15 (TTM As of Dec. 2025)


TLSA Tiziana Life Sciences Ltd TLSA
30 GF Score
Price $1.20
! 2 Warning Signs
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What is Tiziana Life Sciences EBITDA per Share?

Tiziana Life Sciences TLSA +4.42% 30 EBITDA per Share is $-0.15 as of Dec. 2025. GuruFocus rates TLSA with a GF Score™ of 30/100. The stock has 2 warning signs investors should review. Among 1,140 Biotechnology companies, Tiziana Life Sciences ranks worse than 70.44% on this metric.

Tiziana Life Sciences's EBITDA per Share for the six months ended in Dec. 2025 was $-0.08. Its EBITDA per Share for the trailing twelve months (TTM) ended in Dec. 2025 was $-0.15.

During the past 3 years, the average EBITDA per Share Growth Rate was -0.70% per year. During the past 5 years, the average EBITDA per Share Growth Rate was 12.40% per year. During the past 10 years, the average EBITDA per Share Growth Rate was -23.50% per year. Please click Growth Rate Calculation Example (GuruFocus) to see how GuruFocus calculates Wal-Mart Stores Inc (WMT)'s revenue growth rate. You can apply the same method to get the EBITDA per Share growth rate using EBITDA per Share data.

The historical rank and industry rank for Tiziana Life Sciences's EBITDA per Share or its related term are showing as below:

TLSA' s 3-Year EBITDA Growth Rate Range Over the Past 10 Years
Min: -278   Med: -27.6   Max: 67.8
Current: -0.7

During the past 13 years, the highest 3-Year average EBITDA per Share Growth Rate of Tiziana Life Sciences was 67.80% per year. The lowest was -278.00% per year. And the median was -27.60% per year.

TLSA's 3-Year EBITDA Growth Rate is ranked worse than
70.44% of 1140 companies
in the Biotechnology industry
Industry Median: 14.95 vs TLSA: -0.70

Tiziana Life Sciences's EBITDA for the six months ended in Dec. 2025 was $-9.08 Mil.

During the past 3 years, the average EBITDA Growth Rate was -5.90% per year. During the past 5 years, the average EBITDA Growth Rate was 9.30% per year. During the past 10 years, the average EBITDA Growth Rate was -6.80% per year. Please click Growth Rate Calculation Example (GuruFocus) to see how GuruFocus calculates Wal-Mart Stores Inc (WMT)'s revenue growth rate. You can apply the same method to get the EBITDA Growth Rate using EBITDA data.

During the past 13 years, the highest 3-Year average EBITDA Growth Rate of Tiziana Life Sciences was 41.80% per year. The lowest was -158.40% per year. And the median was -2.80% per year.


Tiziana Life Sciences  (NAS:TLSA) EBITDA per Share Explanation

EBITDA is a cash flow measure that ignores changes in working capital. EBITDA minus Depreciation, and Amortization (DA) equals EBIT. EBIT is profit before interest and taxes. Of course, Interest and taxes need to be paid.

While depreciation and amortization expenses do not need to be paid in cash, assets - especially tangible assets - do need to be replaced over time. EBITDA is not a measure of profit in any sense. EBITDA is a measure of cash generation by a business where the uses of that cash may be more or less discretionary depending on the nature of the business.

The EBITDA of a TV station is largely discretionary. Owners may use much of the EBITDA generated by a TV station as they see fit. The EBITDA of a railroad is largely non-discretionary. Owners must use much of the EBITDA generated by a railroad to replace the physical assets of the railroad or the business will literally fall apart over time.

EBITDA can be thought of as the cash a business generates that is available to:

Add more inventory
Add more receivables
Replace property, plant, and equipment
Add more property, plant, and equipment
Pay interest
Pay taxes
And finally: pay owners

EBITDA is widely used in financial analysis because Depreciation and Amortization are not present day cash expenses. Depreciation and amortization are the spreading out of the costs of assets over the time in which those assets provide benefits. Today's depreciation and amortization expenses relate to assets bought in the past. The assets being expensed may or may not need to be replaced in the future. And the cost to replace the assets may be more or less than it was in the past. For this reason, the depreciation and amortization expenses a company records in the present year may have no relationship to the actual cash costs needed to maintain its assets in future years.

A company's depreciation expense depends on both its expectations about the assets it owns and its choice of accounting methods. Two companies owning identical assets may have different depreciation expenses because they have different expectations about the useful lives of those assets and because they make different accounting choices.

Analysts use EBITDA to remove this element of personal choice from a company's accounting statements. The use of EBITDA is an attempt to make the results of different companies more comparable and uniform.


Be Aware

Although depreciation is not a cash cost, it is a real business cost because the company has to pay for the fixed assets when they purchase them. Both Warren Buffett and Charlie Munger hate the idea of EBITDA because in this calculation, depreciation is not counted as an expense.

EBITDA over Revenue is a good metric for comparing the operating efficiencies between companies because EBITDA is less vulnerable to companies' accounting choices. For this reason, EBITDA is used in ranking the Predictability of Companies.


Tiziana Life Sciences EBITDA per Share Related Terms


Tiziana Life Sciences EBITDA per Share Historical Data

* Premium members only.

The historical data trend for Tiziana Life Sciences's EBITDA per Share can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Tiziana Life Sciences EBITDA per Share Chart

Tiziana Life Sciences Annual Data
Trend Dec16 Dec17 Dec18 Dec19 Dec20 Dec21 Dec22 Dec23 Dec24 Dec25
EBITDA per Share
Get a 7-Day Free Trial Premium Member Only Premium Member Only -0.27 -0.15 -0.17 -0.16 -0.15

Tiziana Life Sciences Semi-Annual Data
Jun16 Dec16 Jun17 Dec17 Jun18 Dec18 Jun19 Dec19 Jun20 Dec20 Jun21 Dec21 Jun22 Dec22 Jun23 Dec23 Jun24 Dec24 Jun25 Dec25
EBITDA per Share Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only -0.08 -0.06 -0.09 -0.08 -0.08
TLSA
30GF Score
Tiziana Life Sciences Ltd TLSA
EBITDA per Share is just one metric. See GF Score™, valuation, warning signs, and more.
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Tiziana Life Sciences EBITDA per Share Calculation

EBITDA per Share is the amount of Earnings Before Interest, Taxes, Depreciation, and Amortization (EBITDA) per outstanding share of the company's stock.

Earnings Before Interest, Taxes, Depreciation, and Amortization (EBITDA) is what the company earns before it expenses interest, taxes, depreciation and amortization.

Tiziana Life Sciences's EBITDA per Share for the fiscal year that ended in Dec. 2025 is calculated as

EBITDA per Share(A: Dec. 2025 )
=EBITDA/Shares Outstanding (Diluted Average)
=-18.179/118.283
=-0.15

Tiziana Life Sciences's EBITDA per Share for the quarter that ended in Dec. 2025 is calculated as

EBITDA per Share(Q: Dec. 2025 )
=EBITDA/Shares Outstanding (Diluted Average)
=-9.081/119.739
=-0.08

EBITDA per Share for the trailing twelve months (TTM) ended in Dec. 2025 adds up the semi-annually data reported by the company within the most recent 12 months, which was $-0.15

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Frequently Asked Questions Learn more about EBITDA per Share →
What does a EBITDA per Share of $-0.15 mean?
Tiziana Life Sciences (TLSA) has a EBITDA per Share of $-0.15 as of Dec. 2025. EBITDA per share is the per-share amount of earnings before interest, taxes, depreciation and amortization. View historical data on Tiziana Life Sciences and its competitors. According to the industry distribution chart, Tiziana Life Sciences ranks #803 out of 1140 companies in the Biotechnology industry, placing it in the top 70.4%.
Is Tiziana Life Sciences' EBITDA per Share too high?
Tiziana Life Sciences' current EBITDA per Share is $-0.15. Based on the distribution chart, Tiziana Life Sciences ranks #803 out of 1140 companies in the Biotechnology industry, which is below the industry midpoint. Overall, Tiziana Life Sciences has a GF Score™ of 30/100, reflecting its overall financial health beyond just this single metric.
How does Tiziana Life Sciences' EBITDA per Share compare to SPRB and MIST?
According to the Biotechnology industry distribution chart, Tiziana Life Sciences ranks #803 out of 1140 companies for EBITDA per Share. This places Tiziana Life Sciences in the lower half of its industry. The industry median EBITDA per Share is 14.95. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good EBITDA per Share for a Biotechnology company?
The median EBITDA per Share among Biotechnology companies is 14.95, based on 1,140 companies in the industry. Companies in the top quartile (top 25%) have a EBITDA per Share significantly above this median, while those in the bottom quartile fall well below. However, EBITDA per Share should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high EBITDA per Share mean?
A high EBITDA per Share can signal that a stock is expensive relative to its fundamentals. EBITDA per share is the per-share amount of earnings before interest, taxes, depreciation and amortization. View historical data on Tiziana Life Sciences and its competitors. For the Biotechnology industry, the median EBITDA per Share is 14.95 — values significantly above this may indicate overvaluation, while values below may suggest a bargain or underlying issues. Tiziana Life Sciences's current EBITDA per Share is $-0.15. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Tiziana Life Sciences stock overvalued right now?
Tiziana Life Sciences (TLSA) has a current EBITDA per Share of $-0.15. The current EBITDA per Share is $-0.15. Tiziana Life Sciences' overall GF Score™ is 30/100 with 2 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is EBITDA per Share calculated?
EBITDA per Share is calculated from a company's financial statements. For Tiziana Life Sciences (TLSA), the current EBITDA per Share is $-0.15 as of Dec. 2025. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Tiziana Life Sciences Business Description

Other Exchanges 0RP:Germany
Address 2 Church Street, Clarendon House, Hamilton, BMU, HM 11
Tiziana Life Sciences Ltd is a clinical-stage biotechnology company that specializes in developing transformative therapies for neurodegenerative and neuroinflammatory diseases. The company's clinical pipeline includes drug assets for Non-Active Secondary Progressive Multiple Sclerosis, Multiple System Atrophy, Alzheimer's, and Amyotrophic Lateral Sclerosis. The company's mission is to design and deliver next-generation immunotherapies for neurodegenerative and neuroinflammatory diseases. The company's main immunotherapeutic candidate, Foralumab (TZLS-401), is being developed for Non-Active Secondary Progressive Multiple Sclerosis, Alzheimer's, and other CNS indications.
30GF Score

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EBITDA per Share is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

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