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Tiziana Life SciencesTLSA +2.64%23 EV-to-OCF is -9.73 as of Aug. 09, 2026. GuruFocus rates TLSA with a GF Score™ of 23/100. The stock has 2 warning signs investors should review. Among 1,407 Biotechnology companies, Tiziana Life Sciences ranks better than 68.51% on this metric.
EV-to-OCF is calculated as enterprise value divided by its cash flow from operations. As of today, Tiziana Life Sciences's Enterprise Value is $124.98 Mil.
Tiziana Life Sciences's Cash Flow from Operations for the trailing twelve months (TTM) ended in Dec. 2025 was $-12.85 Mil. Therefore, Tiziana Life Sciences's EV-to-OCF for today is -9.73.
The historical rank and industry rank for Tiziana Life Sciences's EV-to-OCF or its related term are showing as below:
TLSA'
s EV-to-OCF Range Over the Past 10 Years
Min: -9.73 Med: 0 Max: -9.73
Current: -9.73
During the past 13 years, the highest EV-to-OCF of Tiziana Life Sciences was -9.73. The lowest was -9.73. And the median was .
TLSA's EV-to-OCF is ranked better than 68.51% of 1407
companies
in the Biotechnology industry
Industry Median: -3.45
vs TLSA: -9.73
EV-to-OCF is a valuation multiple that allows analysts and investors to compare stocks, preferably in the same sector or industry. This important multiple is often used in conjunction with, or as an alternative to, the PE Ratio (TTM) to determine the fair market value of a company.
Tiziana Life Sciences (NAS:TLSA) EV-to-OCF Explanation
EV-to-OCF is a valuation multiple that allows analysts and investors to compare stocks, preferably in the same sector or industry. This important multiple is often used in conjunction with, or as an alternative to, the PE Ratio (TTM) to determine the fair market value of a company.
Tiziana Life Sciences's PE Ratio (TTM) for today is calculated as:
Tiziana Life Sciences's share price for today is $1.01.
For company reported semi-annually, GuruFocus uses latest annual data as the TTM data. Tiziana Life Sciences's Earnings per Share (Diluted) for the trailing twelve months (TTM) ended in Dec. 2025 was $-0.160.
* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD. * For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.
Enterprise Value is used because it is a more complete measure in reflecting how much an investor pays when buying a company. Cash Flow from Operations is an important financial metric because it represents the cash generated from operating activities at a company's disposal. Companies with a low EV-to-OCF ratio, combined with a strong balance sheet are generally considered as undervalued.
* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD. * For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.
For the Biotechnology subindustry, Tiziana Life Sciences's EV-to-OCF, along with its competitors' market caps and EV-to-OCF data, can be viewed below:
* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.
Tiziana Life Sciences EV-to-OCF vs Biotechnology Industry
For the Biotechnology industry and Healthcare sector, Tiziana Life Sciences's EV-to-OCF distribution charts can be found below:
* The bar in red indicates where Tiziana Life Sciences's EV-to-OCF falls into.
Tiziana Life Sciences's current Enterprise Value is $124.98 Mil.
For company reported semi-annually, GuruFocus uses latest annual data as the TTM data. Tiziana Life Sciences's Cash Flow from Operations for the trailing twelve months (TTM) ended in Dec. 2025 was $-12.85 Mil.
* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD. * For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.
Tiziana Life Sciences (TLSA) has a EV-to-OCF of -9.73 as of Aug. 09, 2026. According to the industry distribution chart, Tiziana Life Sciences ranks #443 out of 1407 companies in the Biotechnology industry, placing it in the top 31.5%.
Is Tiziana Life Sciences' EV-to-OCF too high?
Tiziana Life Sciences' current EV-to-OCF is -9.73. Based on the distribution chart, Tiziana Life Sciences ranks #443 out of 1407 companies in the Biotechnology industry, which is above the industry midpoint. Overall, Tiziana Life Sciences has a GF Score™ of 23/100, reflecting its overall financial health beyond just this single metric.
How does Tiziana Life Sciences' EV-to-OCF compare to PMN and FBIO?
According to the Biotechnology industry distribution chart, Tiziana Life Sciences ranks #443 out of 1407 companies for EV-to-OCF. This puts Tiziana Life Sciences in the upper half of its industry. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good EV-to-OCF for a Biotechnology company?
A good EV-to-OCF depends on the Biotechnology industry context. However, EV-to-OCF should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high EV-to-OCF mean?
A high EV-to-OCF can signal that a stock is expensive relative to its fundamentals. Tiziana Life Sciences's current EV-to-OCF is -9.73. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Tiziana Life Sciences stock overvalued right now?
Tiziana Life Sciences (TLSA) has a current EV-to-OCF of -9.73. The current EV-to-OCF is -9.73. Tiziana Life Sciences' overall GF Score™ is 23/100 with 2 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is EV-to-OCF calculated?
EV-to-OCF is calculated from a company's financial statements. For Tiziana Life Sciences (TLSA), the current EV-to-OCF is -9.73 as of Aug. 09, 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.
Tiziana Life Sciences Ltd is a clinical-stage biotechnology company that specializes in developing transformative therapies for neurodegenerative and neuroinflammatory diseases. The company's clinical pipeline includes drug assets for Non-Active Secondary Progressive Multiple Sclerosis, Multiple System Atrophy, Alzheimer's, and Amyotrophic Lateral Sclerosis. The company's mission is to design and deliver next-generation immunotherapies for neurodegenerative and neuroinflammatory diseases. The company's main immunotherapeutic candidate, Foralumab (TZLS-401), is being developed for Non-Active Secondary Progressive Multiple Sclerosis, Alzheimer's, and other CNS indications.
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