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Tiziana Life SciencesTLSA +4.86%23 3-Year Share Buyback Ratio is -6.20 as of Dec. 2025. GuruFocus rates TLSA with a GF Score™ of 23/100. The stock has 2 warning signs investors should review. Among 1,196 Biotechnology companies, Tiziana Life Sciences ranks better than 62.29% on this metric.
Shares Outstanding (EOP) are shares that have been authorized, issued, and purchased by investors and are held by them.
3-Year Share Buyback Ratio measures the average annual proportion of a company's outstanding shares repurchased over the past three years. It is calculated as the annualized percentage change in shares outstanding from three years ago to the current year. A positive ratio may indicate share buybacks over the period, while a zero or negative ratio may reflect no repurchases or potential share issuance. Tiziana Life Sciences's current 3-Year Share Buyback Ratio was -6.20%.
The historical rank and industry rank for Tiziana Life Sciences's 3-Year Share Buyback Ratio or its related term are showing as below:
TLSA'
s 3-Year Share Buyback Ratio Range Over the Past 10 Years
Min: -210.8 Med: -13.8 Max: 68.5
Current: -6.2
During the past 13 years, Tiziana Life Sciences's highest 3-Year Share Buyback Ratio was 68.50%. The lowest was -210.80%. And the median was -13.80%.
TLSA's 3-Year Share Buyback Ratio is ranked better than 62.29% of 1196
companies
in the Biotechnology industry
Industry Median: -11.65
vs TLSA: -6.20
Tiziana Life Sciences (NAS:TLSA) 3-Year Share Buyback Ratio Explanation
A negative number means the company might be issuing new shares. A positive number indicates that the company is buying back shares.
Be Aware
Investors usually like share buybacks. But as pointed by Warren Buffett, only if a company buys back shares at the prices below the stock's intrinsic value, it rewards remaining shareholders. If a company buys its overvalued stocks back, it destroys shareholder value.
Tiziana Life Sciences 3-Year Share Buyback Ratio Related Terms
TLSA vs PMN, FBIO, VANI: 3-Year Share Buyback Ratio Comparison
For the Biotechnology subindustry, Tiziana Life Sciences's 3-Year Share Buyback Ratio, along with its competitors' market caps and 3-Year Share Buyback Ratio data, can be viewed below:
* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.
Tiziana Life Sciences 3-Year Share Buyback Ratio vs Biotechnology Industry
For the Biotechnology industry and Healthcare sector, Tiziana Life Sciences's 3-Year Share Buyback Ratio distribution charts can be found below:
* The bar in red indicates where Tiziana Life Sciences's 3-Year Share Buyback Ratio falls into.
Tiziana Life Sciences 3-Year Share Buyback Ratio Calculation
This is the annualized percentage change in shares outstanding from three years ago to the current year. The annualized percentage change is calculated with expontential compound based on the latest four years of annual data on Shares Outstanding (EOP).
Please click Growth Rate Calculation Example (GuruFocus) to see how GuruFocus calculates Wal-Mart Stores Inc (WMT)'s revenue growth rate. You can apply the same method to get the average dividends per share growth rate.
What does a 3-Year Share Buyback Ratio of -6.20 mean?
Tiziana Life Sciences (TLSA) has a 3-Year Share Buyback Ratio of -6.20 as of Dec. 2025. The 3-Year Share Buyback Ratio measures the average annual proportion of a company's outstanding shares repurchased over the past three years. It is calculated as the annualized percentage change in shares outstanding from three years ago to the current year. View historical data for Tiziana Life Sciences and its competitors. According to the industry distribution chart, Tiziana Life Sciences ranks #451 out of 1196 companies in the Biotechnology industry, placing it in the top 37.7%.
Is Tiziana Life Sciences' 3-Year Share Buyback Ratio too high?
Tiziana Life Sciences' current 3-Year Share Buyback Ratio is -6.20. Based on the distribution chart, Tiziana Life Sciences ranks #451 out of 1196 companies in the Biotechnology industry, which is above the industry midpoint. Overall, Tiziana Life Sciences has a GF Score™ of 23/100, reflecting its overall financial health beyond just this single metric.
How does Tiziana Life Sciences' 3-Year Share Buyback Ratio compare to PMN and FBIO?
According to the Biotechnology industry distribution chart, Tiziana Life Sciences ranks #451 out of 1196 companies for 3-Year Share Buyback Ratio. This puts Tiziana Life Sciences in the upper half of its industry. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good 3-Year Share Buyback Ratio for a Biotechnology company?
A good 3-Year Share Buyback Ratio depends on the Biotechnology industry context. However, 3-Year Share Buyback Ratio should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high 3-Year Share Buyback Ratio mean?
A high 3-Year Share Buyback Ratio can signal that a stock is expensive relative to its fundamentals. The 3-Year Share Buyback Ratio measures the average annual proportion of a company's outstanding shares repurchased over the past three years. It is calculated as the annualized percentage change in shares outstanding from three years ago to the current year. View historical data for Tiziana Life Sciences and its competitors. Tiziana Life Sciences's current 3-Year Share Buyback Ratio is -6.20. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Tiziana Life Sciences stock overvalued right now?
Tiziana Life Sciences (TLSA) has a current 3-Year Share Buyback Ratio of -6.20. The current 3-Year Share Buyback Ratio is -6.20. Tiziana Life Sciences' overall GF Score™ is 23/100 with 2 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is 3-Year Share Buyback Ratio calculated?
3-Year Share Buyback Ratio is calculated from a company's financial statements. For Tiziana Life Sciences (TLSA), the current 3-Year Share Buyback Ratio is -6.20 as of Dec. 2025. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.
Tiziana Life Sciences Ltd is a clinical-stage biotechnology company that specializes in developing transformative therapies for neurodegenerative and neuroinflammatory diseases. The company's clinical pipeline includes drug assets for Non-Active Secondary Progressive Multiple Sclerosis, Multiple System Atrophy, Alzheimer's, and Amyotrophic Lateral Sclerosis. The company's mission is to design and deliver next-generation immunotherapies for neurodegenerative and neuroinflammatory diseases. The company's main immunotherapeutic candidate, Foralumab (TZLS-401), is being developed for Non-Active Secondary Progressive Multiple Sclerosis, Alzheimer's, and other CNS indications.
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