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SeaStar Medical HoldingICU -6.07%29 EV-to-EBITDA is -0.25 as of Aug. 05, 2026. GuruFocus rates ICU with a GF Score™ of 29/100. The stock has 4 warning signs investors should review. Among 411 Biotechnology companies, SeaStar Medical Holding ranks worse than 243308.76% on this metric.
EV-to-EBITDA is calculated as enterprise value divided by its EBITDA. As of today, SeaStar Medical Holding's enterprise value is $2.95 Mil.
SeaStar Medical Holding's EBITDA for the trailing twelve months (TTM) ended in Mar. 2026 was $-11.87 Mil. Therefore, SeaStar Medical Holding's EV-to-EBITDA for today is -0.25.
The historical rank and industry rank for SeaStar Medical Holding's EV-to-EBITDA or its related term are showing as below:
ICU'
s EV-to-EBITDA Range Over the Past 10 Years
Min: -0.87 Med: -0.27 Max: 0.53
Current: -0.25
During the past 6 years, the highest EV-to-EBITDA of SeaStar Medical Holding was 0.53. The lowest was -0.87. And the median was -0.27.
ICU's EV-to-EBITDA is ranked worse than 100% of 411
companies
in the Biotechnology industry
Industry Median: 12.78
vs ICU: -0.25
EV-to-EBITDA is a valuation multiple used in finance and investment to measure the value of a company. This important multiple is often used in conjunction with, or as an alternative to, the PE Ratio to determine the fair market value of a company.
SeaStar Medical Holding (NAS:ICU) EV-to-EBITDA Explanation
EV-to-EBITDA is a valuation multiple used in finance and investment to measure the value of a company. This important multiple is often used in conjunction with, or as an alternative to, the PE Ratio (TTM) to determine the fair market value of a company.
SeaStar Medical Holding's PE Ratio (TTM) for today is calculated as:
SeaStar Medical Holding's share price for today is $3.02.
SeaStar Medical Holding's Earnings per Share (Diluted) for the trailing twelve months (TTM) ended in Mar. 2026 adds up the quarterly data reported by the company within the most recent 12 months, which was $-4.800.
* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD. * For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.
Study has found that the companies with the lowest EV-to-EBITDA outperforms companies measured as cheap by other ratios such as PE Ratio (TTM).
* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD. * For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.
For the Biotechnology subindustry, SeaStar Medical Holding's EV-to-EBITDA, along with its competitors' market caps and EV-to-EBITDA data, can be viewed below:
* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.
SeaStar Medical Holding EV-to-EBITDA vs Biotechnology Industry
For the Biotechnology industry and Healthcare sector, SeaStar Medical Holding's EV-to-EBITDA distribution charts can be found below:
* The bar in red indicates where SeaStar Medical Holding's EV-to-EBITDA falls into.
SeaStar Medical Holding's current Enterprise Value is $2.95 Mil.
SeaStar Medical Holding's EBITDA for the trailing twelve months (TTM) ended in Mar. 2026 adds up the quarterly data reported by the company within the most recent 12 months, which was $-11.87 Mil.
* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD. * For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.
SeaStar Medical Holding (ICU) has a EV-to-EBITDA of -0.25 as of Aug. 05, 2026. EV to EBITDA ratio is the company's enterprise value divided by earnings before interest, taxes, depreciation and amortization. View historical data on SeaStar Medical Holding. According to the industry distribution chart, SeaStar Medical Holding ranks #999999 out of 411 companies in the Biotechnology industry.
Is SeaStar Medical Holding's EV-to-EBITDA too high?
SeaStar Medical Holding's current EV-to-EBITDA is -0.25. Based on the distribution chart, SeaStar Medical Holding ranks #999999 out of 411 companies in the Biotechnology industry, which is in the bottom quartile relative to peers. Overall, SeaStar Medical Holding has a GF Score™ of 29/100, reflecting its overall financial health beyond just this single metric.
How does SeaStar Medical Holding's EV-to-EBITDA compare to TPST and OSRH?
According to the Biotechnology industry distribution chart, SeaStar Medical Holding ranks #999999 out of 411 companies for EV-to-EBITDA. This places SeaStar Medical Holding in the lower half of its industry. The industry median EV-to-EBITDA is 12.78. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good EV-to-EBITDA for a Biotechnology company?
The median EV-to-EBITDA among Biotechnology companies is 12.78, based on 411 companies in the industry. Companies in the top quartile (top 25%) have a EV-to-EBITDA significantly above this median, while those in the bottom quartile fall well below. However, EV-to-EBITDA should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high EV-to-EBITDA mean?
A high EV-to-EBITDA can signal that a stock is expensive relative to its fundamentals. EV to EBITDA ratio is the company's enterprise value divided by earnings before interest, taxes, depreciation and amortization. View historical data on SeaStar Medical Holding. For the Biotechnology industry, the median EV-to-EBITDA is 12.78 — values significantly above this may indicate overvaluation, while values below may suggest a bargain or underlying issues. SeaStar Medical Holding's current EV-to-EBITDA is -0.25. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is SeaStar Medical Holding stock overvalued right now?
SeaStar Medical Holding (ICU) has a current EV-to-EBITDA of -0.25. The current EV-to-EBITDA is -0.25. SeaStar Medical Holding's overall GF Score™ is 29/100 with 4 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is EV-to-EBITDA calculated?
EV-to-EBITDA is calculated from a company's financial statements. For SeaStar Medical Holding (ICU), the current EV-to-EBITDA is -0.25 as of Aug. 05, 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.
SeaStar Medical Holding Corp is a medical technology company developing proprietary solutions to reduce the consequences of hyperinflammation on vital organs. It is developing and commercializing extracorporeal therapies that target the effector cells that drive systemic inflammation, causing direct tissue damage and secreting a range of pro-inflammatory cytokines that initiate and propagate imbalanced immune responses. The Company is comprised of a single reportable segment, which is its Device Segment.
29GF Score
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