ICU (SeaStar Medical Holding) Return-on-Tangible-Equity: -158.86% (As of Mar. 2026)


ICU SeaStar Medical Holding Corp ICU
32 GF Score
Price $4.92
! 4 Warning Signs
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What is SeaStar Medical Holding Return-on-Tangible-Equity?

SeaStar Medical Holding ICU +0.92% 32 Return-on-Tangible-Equity is -158.86% as of Mar. 2026. GuruFocus rates ICU with a GF Score™ of 32/100. The stock has 4 warning signs investors should review. Among 1,196 Biotechnology companies, SeaStar Medical Holding ranks worse than 84.03% on this metric.

Return-on-Tangible-Equity is calculated as Net Income divided by its average total shareholder tangible equity. Total shareholder tangible equity equals to Total Stockholders Equity minus Intangible Assets. SeaStar Medical Holding's annualized net income for the quarter that ended in Mar. 2026 was $-14.08 Mil. SeaStar Medical Holding's average shareholder tangible equity for the quarter that ended in Mar. 2026 was $8.87 Mil. Therefore, SeaStar Medical Holding's annualized Return-on-Tangible-Equity for the quarter that ended in Mar. 2026 was -158.86%.

The historical rank and industry rank for SeaStar Medical Holding's Return-on-Tangible-Equity or its related term are showing as below:

ICU' s Return-on-Tangible-Equity Range Over the Past 10 Years
Min: -295.15   Med: -295.15   Max: -179.74
Current: -179.74

During the past 6 years, SeaStar Medical Holding's highest Return-on-Tangible-Equity was -179.74%. The lowest was -295.15%. And the median was -295.15%.

ICU's Return-on-Tangible-Equity is ranked worse than
84.03% of 1196 companies
in the Biotechnology industry
Industry Median: -42.19 vs ICU: -179.74

SeaStar Medical Holding  (NAS:ICU) Return-on-Tangible-Equity Explanation

Return-on-Tangible-Equity measures the rate of return on the ownership interest (shareholder's tangible equity) of the common stock owners. It measures a firm's efficiency at generating profits from every unit of shareholders' tangible equity (shareholders equity minus intangibles). Return-on-Tangible-Equity shows how well a company uses investment funds to generate earnings growth. Return-on-Tangible-Equitys between 15% and 20% are considered desirable.


Be Aware

Net Income is used.

Because a company can increase its Return-on-Tangible-Equity by having more financial leverage, it is important to watch the leverage ratio when investing in high Return-on-Tangible-Equity companies. Like Return-on-Tangible-Asset, Return-on-Tangible-Equity is calculated with only 12 months data. Fluctuations in company's earnings or business cycles can affect the ratio drastically. It is important to look at the ratio from a long term perspective.

Asset light businesses require very few assets to generate very high earnings. Their Return-on-Tangible-Equitys can be extremely high.


SeaStar Medical Holding Return-on-Tangible-Equity Related Terms


SeaStar Medical Holding Return-on-Tangible-Equity Historical Data

* Premium members only.

The historical data trend for SeaStar Medical Holding's Return-on-Tangible-Equity can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

SeaStar Medical Holding Return-on-Tangible-Equity Chart

SeaStar Medical Holding Annual Data
Trend Dec20 Dec21 Dec22 Dec23 Dec24 Dec25
Return-on-Tangible-Equity
Get a 7-Day Free Trial 0.00 0.00 0.00 0.00 -295.15

SeaStar Medical Holding Quarterly Data
Mar21 Jun21 Dec21 Mar22 Jun22 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Sep24 Dec24 Mar25 Jun25 Sep25 Dec25 Mar26
Return-on-Tangible-Equity Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only 0.00 -410.04 -187.61 -106.18 -158.86

ICU vs TRAW, CALC, INAB: Return-on-Tangible-Equity Comparison

For the Biotechnology subindustry, SeaStar Medical Holding's Return-on-Tangible-Equity, along with its competitors' market caps and Return-on-Tangible-Equity data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


SeaStar Medical Holding Return-on-Tangible-Equity vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, SeaStar Medical Holding's Return-on-Tangible-Equity distribution charts can be found below:

* The bar in red indicates where SeaStar Medical Holding's Return-on-Tangible-Equity falls into.


ICU
32GF Score
SeaStar Medical Holding Corp ICU
Return-on-Tangible-Equity is just one metric. See GF Score™, valuation, warning signs, and more.
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SeaStar Medical Holding Return-on-Tangible-Equity Calculation

SeaStar Medical Holding's annualized Return-on-Tangible-Equity for the fiscal year that ended in Dec. 2025 is calculated as

Return-on-Tangible-Equity=Net Income/( (Total Tangible Equity+Total Tangible Equity)/ count )
(A: Dec. 2025 )  (A: Dec. 2024 )(A: Dec. 2025 )
=Net Income/( (Total Stockholders Equity - Intangible Assets+Total Stockholders Equity - Intangible Assets )/ count )
(A: Dec. 2025 )  (A: Dec. 2024 )(A: Dec. 2025 )
=-12.15/( (-2.183+10.416 )/ 2 )
=-12.15/4.1165
=-295.15 %

SeaStar Medical Holding's annualized Return-on-Tangible-Equity for the quarter that ended in Mar. 2026 is calculated as

Return-on-Tangible-Equity=Net Income/( (Total Tangible Equity+Total Tangible Equity)/ count )
(Q: Mar. 2026 )  (Q: Dec. 2025 )(Q: Mar. 2026 )
=Net Income/( (Total Stockholders Equity - Intangible Assets+Total Stockholders Equity - Intangible Assets)/ count )
(Q: Mar. 2026 )  (Q: Dec. 2025 )(Q: Mar. 2026 )
=-14.084/( (10.416+7.315)/ 2 )
=-14.084/8.8655
=-158.86 %

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

In the calculation of annual Return-on-Tangible-Equity, the net income of the last fiscal year and the average total shareholder tangible equity over the fiscal year are used. In calculating the quarterly data, the net income data used here is four times the quarterly (Mar. 2026) net income data. Return-on-Tangible-Equity is displayed in the 10-year financial page.

What does a Return-on-Tangible-Equity of -158.86% mean?
SeaStar Medical Holding (ICU) has a Return-on-Tangible-Equity of -158.86% as of Mar. 2026. Return on tangible equity is the ratio of current-period net income to average two-period tangible equity. View historical data on SeaStar Medical Holding and its competitors. According to the industry distribution chart, SeaStar Medical Holding ranks #1005 out of 1196 companies in the Biotechnology industry, placing it in the top 84%.
Is SeaStar Medical Holding's Return-on-Tangible-Equity too high?
SeaStar Medical Holding's current Return-on-Tangible-Equity is -158.86%. Based on the distribution chart, SeaStar Medical Holding ranks #1005 out of 1196 companies in the Biotechnology industry, which is in the bottom quartile relative to peers. Overall, SeaStar Medical Holding has a GF Score™ of 32/100, reflecting its overall financial health beyond just this single metric.
How does SeaStar Medical Holding's Return-on-Tangible-Equity compare to TRAW and CALC?
According to the Biotechnology industry distribution chart, SeaStar Medical Holding ranks #1005 out of 1196 companies for Return-on-Tangible-Equity. This places SeaStar Medical Holding in the lower half of its industry. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good Return-on-Tangible-Equity for a Biotechnology company?
A good Return-on-Tangible-Equity depends on the Biotechnology industry context. However, Return-on-Tangible-Equity should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high Return-on-Tangible-Equity mean?
A high Return-on-Tangible-Equity can signal that a stock is expensive relative to its fundamentals. Return on tangible equity is the ratio of current-period net income to average two-period tangible equity. View historical data on SeaStar Medical Holding and its competitors. SeaStar Medical Holding's current Return-on-Tangible-Equity is -158.86%. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is SeaStar Medical Holding stock overvalued right now?
SeaStar Medical Holding (ICU) has a current Return-on-Tangible-Equity of -158.86%. The current Return-on-Tangible-Equity is -158.86%. SeaStar Medical Holding's overall GF Score™ is 32/100 with 4 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is Return-on-Tangible-Equity calculated?
Return-on-Tangible-Equity is calculated from a company's financial statements. For SeaStar Medical Holding (ICU), the current Return-on-Tangible-Equity is -158.86% as of Mar. 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

SeaStar Medical Holding Business Description

Address 3513 Brighton Boulevard, Suite 410, Denver, CO, USA, 80216
SeaStar Medical Holding Corp is a medical technology company developing proprietary solutions to reduce the consequences of hyperinflammation on vital organs. It is developing and commercializing extracorporeal therapies that target the effector cells that drive systemic inflammation, causing direct tissue damage and secreting a range of pro-inflammatory cytokines that initiate and propagate imbalanced immune responses. The Company is comprised of a single reportable segment, which is its Device Segment.
32GF Score

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Return-on-Tangible-Equity is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

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