SeaStar Medical HoldingICU +1.02%32 3-Year ROIIC % is 4.57 as of Dec. 2025, which is at its 10-year median of 4.57. GuruFocus rates ICU with a GF Score™ of 32/100. The stock has 4 warning signs investors should review. Among 1,321 Biotechnology companies, SeaStar Medical Holding ranks better than 57.61% on this metric.
3-Year Return on Invested Incremental Capital (3-Year ROIIC %) measures the change in earnings as a percentage of change in investment over 3-year.
SeaStar Medical Holding's 3-Year ROIIC % for the quarter that ended in Dec. 2025 was 4.57%. High ROIIC is generally an indication that your business is capital efficient or has a higher operating leverage.
The industry rank for SeaStar Medical Holding's 3-Year ROIIC % or its related term are showing as below:
ICU's 3-Year ROIIC % is ranked better than 57.61% of 1321
companies
in the Biotechnology industry
Industry Median: -4.44
vs ICU: 4.57
SeaStar Medical Holding (NAS:ICU) 3-Year ROIIC % Explanation
Return on Incremental Invested Capital (ROIIC) is an extension of Return on Investment Capital (ROIC). ROIC % tells investors how efficiently that profitability is earned per dollar of company capital. ROIIC narrows the focus even further and shows how profitable each additional unit of capital investment could be. ROIIC % is a more powerful metric than ROIC because it measures how much money the company can generate going forward on future capital investments.
High ROIIC is generally an indication that your business is capital efficient or has a higher operating leverage.
Be Aware
It's important to keep in mind that when tracking ROIIC, the metric is better suited to forecasting the trend of future returns rather than measuring current return on investment.
SeaStar Medical Holding 3-Year ROIIC % Related Terms
SeaStar Medical Holding 3-Year ROIIC % Historical Data
* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD. * For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.
ICU vs TRAW, CALC, INAB: 3-Year ROIIC % Comparison
For the Biotechnology subindustry, SeaStar Medical Holding's 3-Year ROIIC %, along with its competitors' market caps and 3-Year ROIIC % data, can be viewed below:
* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.
SeaStar Medical Holding 3-Year ROIIC % vs Biotechnology Industry
For the Biotechnology industry and Healthcare sector, SeaStar Medical Holding's 3-Year ROIIC % distribution charts can be found below:
* The bar in red indicates where SeaStar Medical Holding's 3-Year ROIIC % falls into.
SeaStar Medical Holding 3-Year ROIIC % Calculation
SeaStar Medical Holding's 3-Year ROIIC % for the quarter that ended in Dec. 2025 is calculated as:
3-Year ROIIC %
=
3-Year Incremental Net Operating Profit After Taxes (NOPAT)**
/
3-Year Incremental Invested Capital**
=
( -12.175 (Dec. 2025) - -11.609 (Dec. 2022) )
/
( 1.104 (Dec. 2025) - 13.495 (Dec. 2022) )
=
-0.566
/
-12.391
=
4.57%***
* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD. * For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.
** Annual data of NOPAT and Invested Capital was used to calculate 3-Year ROIIC %.
*** Please be aware that the ROIIC (Return on Invested Capital) calculations are based on company-level data using the primary share class. The calculated data provided is for demonstration purposes and may slightly differ from the results displayed in the title due to potential variations caused by currency exchange rate differences throughout the year.
SeaStar Medical Holding (ICU) has a 3-Year ROIIC % of 4.57 as of Dec. 2025. 3-Year ROIIC % measures the change in earnings as a percentage of change in investment over 3-year. View historical data on SeaStar Medical Holding and its competitors. This is near median its historical median of 4.57. According to the industry distribution chart, SeaStar Medical Holding ranks #560 out of 1321 companies in the Biotechnology industry, placing it in the top 42.4%.
Is SeaStar Medical Holding's 3-Year ROIIC % too high?
SeaStar Medical Holding's current 3-Year ROIIC % of 4.57 is near median its 10-year median of 4.57. Based on the distribution chart, SeaStar Medical Holding ranks #560 out of 1321 companies in the Biotechnology industry, which is above the industry midpoint. Overall, SeaStar Medical Holding has a GF Score™ of 32/100, reflecting its overall financial health beyond just this single metric.
How does SeaStar Medical Holding's 3-Year ROIIC % compare to TRAW and CALC?
According to the Biotechnology industry distribution chart, SeaStar Medical Holding ranks #560 out of 1321 companies for 3-Year ROIIC %. This puts SeaStar Medical Holding in the upper half of its industry. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good 3-Year ROIIC % for a Biotechnology company?
A good 3-Year ROIIC % depends on the Biotechnology industry context. However, 3-Year ROIIC % should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high 3-Year ROIIC % mean?
A high 3-Year ROIIC % can signal that a stock is expensive relative to its fundamentals. 3-Year ROIIC % measures the change in earnings as a percentage of change in investment over 3-year. View historical data on SeaStar Medical Holding and its competitors. SeaStar Medical Holding's current 3-Year ROIIC % is 4.57, which is near median its own 10-year median of 4.57. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is SeaStar Medical Holding stock overvalued right now?
SeaStar Medical Holding (ICU) has a current 3-Year ROIIC % of 4.57. The current 3-Year ROIIC % is 4.57, which is near median its 10-year median of 4.57. SeaStar Medical Holding's overall GF Score™ is 32/100 with 4 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is 3-Year ROIIC % calculated?
3-Year ROIIC % is calculated from a company's financial statements. For SeaStar Medical Holding (ICU), the current 3-Year ROIIC % is 4.57 as of Dec. 2025. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.
SeaStar Medical Holding Corp is a medical technology company developing proprietary solutions to reduce the consequences of hyperinflammation on vital organs. It is developing and commercializing extracorporeal therapies that target the effector cells that drive systemic inflammation, causing direct tissue damage and secreting a range of pro-inflammatory cytokines that initiate and propagate imbalanced immune responses. The Company is comprised of a single reportable segment, which is its Device Segment.
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