ICU (SeaStar Medical Holding) ROE % Adjusted to Book Value: -78.26% (As of Mar. 2026)


ICU SeaStar Medical Holding Corp ICU
31 GF Score
Price $3.18
! 4 Warning Signs
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What is SeaStar Medical Holding ROE % Adjusted to Book Value?

SeaStar Medical Holding ICU +4.70% 31 ROE % Adjusted to Book Value is -78.26% as of Mar. 2026. GuruFocus rates ICU with a GF Score™ of 31/100. The stock has 4 warning signs investors should review.

SeaStar Medical Holding's ROE % for the quarter that ended in Mar. 2026 was -158.86%. SeaStar Medical Holding's PB Ratio for the quarter that ended in Mar. 2026 was 2.03. SeaStar Medical Holding's ROE % Adjusted to Book Value for the quarter that ended in Mar. 2026 was -78.26%.

SeaStar Medical Holding ROE % Adjusted to Book Value Related Terms

SeaStar Medical Holding ROE % Adjusted to Book Value Historical Data

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The historical data trend for SeaStar Medical Holding's ROE % Adjusted to Book Value can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

SeaStar Medical Holding ROE % Adjusted to Book Value Chart

SeaStar Medical Holding Annual Data
Trend Dec20 Dec21 Dec22 Dec23 Dec24 Dec25
ROE % Adjusted to Book Value
Get a 7-Day Free Trial 0.00 0.00 0.00 0.00 -331.63

SeaStar Medical Holding Quarterly Data
Mar21 Jun21 Dec21 Mar22 Jun22 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Sep24 Dec24 Mar25 Jun25 Sep25 Dec25 Mar26
ROE % Adjusted to Book Value Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only 0.00 -185.54 -110.36 -119.30 -78.26

ICU vs MBRX, LEXX, INTI: ROE % Adjusted to Book Value Comparison

For the Biotechnology subindustry, SeaStar Medical Holding's ROE % Adjusted to Book Value, along with its competitors' market caps and ROE % Adjusted to Book Value data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.

SeaStar Medical Holding ROE % Adjusted to Book Value vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, SeaStar Medical Holding's ROE % Adjusted to Book Value distribution charts can be found below:

* The bar in red indicates where SeaStar Medical Holding's ROE % Adjusted to Book Value falls into.


ICU
31GF Score
SeaStar Medical Holding Corp ICU
ROE % Adjusted to Book Value is just one metric. See GF Score™, valuation, warning signs, and more.
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SeaStar Medical Holding ROE % Adjusted to Book Value Calculation

SeaStar Medical Holding's ROE % Adjusted to Book Value for the fiscal year that ended in Dec. 2025 is calculated as

ROE % Adjusted to Book Value=ROE % / PB Ratio
=-295.15% / 0.89
=-331.63%

SeaStar Medical Holding's ROE % Adjusted to Book Value for the quarter that ended in Mar. 2026 is calculated as

ROE % Adjusted to Book Value=ROE % / PB Ratio
=-158.86% / 2.03
=-78.26%

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

What does a ROE % Adjusted to Book Value of -78.26% mean?
SeaStar Medical Holding (ICU) has a ROE % Adjusted to Book Value of -78.26% as of Mar. 2026. Return on equity adjusted to book is the ratio of return on equity to price-book ratio. View historical data on SeaStar Medical Holding and its competitors.
Is SeaStar Medical Holding's ROE % Adjusted to Book Value too high?
SeaStar Medical Holding's current ROE % Adjusted to Book Value is -78.26%. Overall, SeaStar Medical Holding has a GF Score™ of 31/100, reflecting its overall financial health beyond just this single metric.
How does SeaStar Medical Holding's ROE % Adjusted to Book Value compare to MBRX and LEXX?
SeaStar Medical Holding's ROE % Adjusted to Book Value of -78.26% can be compared against companies in the Biotechnology industry. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good ROE % Adjusted to Book Value for a Biotechnology company?
A good ROE % Adjusted to Book Value depends on the Biotechnology industry context. However, ROE % Adjusted to Book Value should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high ROE % Adjusted to Book Value mean?
A high ROE % Adjusted to Book Value can signal that a stock is expensive relative to its fundamentals. Return on equity adjusted to book is the ratio of return on equity to price-book ratio. View historical data on SeaStar Medical Holding and its competitors. SeaStar Medical Holding's current ROE % Adjusted to Book Value is -78.26%. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is SeaStar Medical Holding stock overvalued right now?
SeaStar Medical Holding (ICU) has a current ROE % Adjusted to Book Value of -78.26%. The current ROE % Adjusted to Book Value is -78.26%. SeaStar Medical Holding's overall GF Score™ is 31/100 with 4 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is ROE % Adjusted to Book Value calculated?
ROE % Adjusted to Book Value is calculated from a company's financial statements. For SeaStar Medical Holding (ICU), the current ROE % Adjusted to Book Value is -78.26% as of Mar. 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

SeaStar Medical Holding Business Description

Address 3513 Brighton Boulevard, Suite 410, Denver, CO, USA, 80216
SeaStar Medical Holding Corp is a medical technology company developing proprietary solutions to reduce the consequences of hyperinflammation on vital organs. It is developing and commercializing extracorporeal therapies that target the effector cells that drive systemic inflammation, causing direct tissue damage and secreting a range of pro-inflammatory cytokines that initiate and propagate imbalanced immune responses. The Company is comprised of a single reportable segment, which is its Device Segment.
31GF Score

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