SeaStar Medical HoldingICU +4.70%29 Gross Margin % is 90.71% as of Mar. 2026, which is 5% below its 10-year median of 95.71. GuruFocus rates ICU with a GF Score™ of 29/100. The stock has 4 warning signs investors should review. Among 737 Biotechnology companies, SeaStar Medical Holding ranks better than 89.96% on this metric.
ICU's Gross Margin % is ranked better than 89.96% of 737
companies
in the Biotechnology industry
Industry Median: 60.92
vs ICU: 93.11
SeaStar Medical Holding had a gross margin of 90.71% for the quarter that ended in Mar. 2026 => Durable competitive advantage
The 5-Year average Growth Rate of Gross Margin for SeaStar Medical Holding was 0.00% per year.
SeaStar Medical Holding (NAS:ICU) Gross Margin % Explanation
Warren Buffett believes that firms with excellent long term economics tend to have consistently higher margins.
Durable competitive advantage creates a high Gross Margin % because of the freedom to price in excess of cost. Companies can be categorized by their Gross Margin %
1. Greater than 40% = Durable competitive advantage
2. Less than 40% = Competition eroding margins
3. Less than 20% = no sustainable competitive advantage
Consistency of Gross Margin is key
SeaStar Medical Holding had a gross margin of 90.71% for the quarter that ended in Mar. 2026 => Durable competitive advantage
Be Aware
If a company loses its competitive advantages, usually its gross margin declines well before its sales declines. Watching Gross Margin % and Operating Margin % closely helps avoid value trap situations.
SeaStar Medical Holding Gross Margin % Related Terms
SeaStar Medical Holding Gross Margin % Historical Data
* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD. * For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.
ICU vs MBRX, LEXX, INTI: Gross Margin % Comparison
For the Biotechnology subindustry, SeaStar Medical Holding's Gross Margin %, along with its competitors' market caps and Gross Margin % data, can be viewed below:
* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.
SeaStar Medical Holding Gross Margin % vs Biotechnology Industry
For the Biotechnology industry and Healthcare sector, SeaStar Medical Holding's Gross Margin % distribution charts can be found below:
* The bar in red indicates where SeaStar Medical Holding's Gross Margin % falls into.
* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD. * For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.
A positive Gross Profit is only the first step for a company to make a net profit. The gross profit needs to be big enough to also cover related labor, equipment, rental, marketing/advertising, research and development and a lot of other costs in selling the products.
SeaStar Medical Holding (ICU) has a Gross Margin % of 90.71% as of Mar. 2026. Gross margin is the ratio of total gross profit to net sales. View historical data on SeaStar Medical Holding and its competitors. This is near median its historical median of 95.71. Over the past decade, SeaStar Medical Holding's Gross Margin % has ranged from 93.11 to 95.71. According to the industry distribution chart, SeaStar Medical Holding ranks #74 out of 737 companies in the Biotechnology industry, placing it in the top 10%.
Is SeaStar Medical Holding's Gross Margin % too high?
SeaStar Medical Holding's current Gross Margin % of 90.71% is near median its 10-year median of 95.71. Over the past 10 years, this metric has ranged from a low of 93.11 to a high of 95.71. The Biotechnology industry median Gross Margin % is 60.92. SeaStar Medical Holding's value of 90.71% is 48.9% above this industry median. Based on the distribution chart, SeaStar Medical Holding ranks #74 out of 737 companies in the Biotechnology industry, which is in the top quartile — a strong position relative to peers. Overall, SeaStar Medical Holding has a GF Score™ of 29/100, reflecting its overall financial health beyond just this single metric.
How does SeaStar Medical Holding's Gross Margin % compare to MBRX and LEXX?
According to the Biotechnology industry distribution chart, SeaStar Medical Holding ranks #74 out of 737 companies for Gross Margin %. This places SeaStar Medical Holding in the top 10% of its industry — outperforming the majority of peers. The industry median Gross Margin % is 60.92. SeaStar Medical Holding's value of 90.71% is 48.9% above this benchmark. Historically, SeaStar Medical Holding's own Gross Margin % has ranged from 93.11 to 95.71 over the past decade. While the company's 10-year median is 95.71 vs. the industry median of 60.92, SeaStar Medical Holding has consistently been above the industry average. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good Gross Margin % for a Biotechnology company?
The median Gross Margin % among Biotechnology companies is 60.92, based on 737 companies in the industry. Companies in the top quartile (top 25%) have a Gross Margin % significantly above this median, while those in the bottom quartile fall well below. However, Gross Margin % should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. SeaStar Medical Holding's current Gross Margin % of 90.71% is 48.9% above the industry median. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high Gross Margin % mean?
A high Gross Margin % can signal that a stock is expensive relative to its fundamentals. Gross margin is the ratio of total gross profit to net sales. View historical data on SeaStar Medical Holding and its competitors. For the Biotechnology industry, the median Gross Margin % is 60.92 — values significantly above this may indicate overvaluation, while values below may suggest a bargain or underlying issues. SeaStar Medical Holding's current Gross Margin % is 90.71%, which is near median its own 10-year median of 95.71. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is SeaStar Medical Holding stock overvalued right now?
SeaStar Medical Holding (ICU) has a current Gross Margin % of 90.71%. The current Gross Margin % is 90.71%, which is near median its 10-year median of 95.71 and 48.9% above the Biotechnology industry median of 60.92. SeaStar Medical Holding's overall GF Score™ is 29/100 with 4 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is Gross Margin % calculated?
Gross Margin % is calculated from a company's financial statements. For SeaStar Medical Holding (ICU), the current Gross Margin % is 90.71% as of Mar. 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.
SeaStar Medical Holding Corp is a medical technology company developing proprietary solutions to reduce the consequences of hyperinflammation on vital organs. It is developing and commercializing extracorporeal therapies that target the effector cells that drive systemic inflammation, causing direct tissue damage and secreting a range of pro-inflammatory cytokines that initiate and propagate imbalanced immune responses. The Company is comprised of a single reportable segment, which is its Device Segment.
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