ICU (SeaStar Medical Holding) Net Margin %: -711.31% (As of Mar. 2026)

What is SeaStar Medical Holding Net Margin %?

SeaStar Medical Holding ICU -3.40% 29 Net Margin % is -711.31% as of Mar. 2026. GuruFocus rates ICU with a GF Score™ of 29/100. The stock has 4 warning signs investors should review. Among 946 Biotechnology companies, SeaStar Medical Holding ranks worse than 76.85% on this metric.

Net margin is calculated as Net Income divided by its Revenue. SeaStar Medical Holding's Net Income for the three months ended in Mar. 2026 was $-3.52 Mil. SeaStar Medical Holding's Revenue for the three months ended in Mar. 2026 was $0.50 Mil. Therefore, SeaStar Medical Holding's net margin for the quarter that ended in Mar. 2026 was -711.31%.

The historical rank and industry rank for SeaStar Medical Holding's Net Margin % or its related term are showing as below:

ICU' s Net Margin % Range Over the Past 10 Years
Min: -18392.59 Med: -9688.6 Max: -828.62
Current: -828.62

ICU's Net Margin % is ranked worse than
76.85% of 946 companies
in the Biotechnology industry
Industry Median: -88.815 vs ICU: -828.62

SeaStar Medical Holding (NAS:ICU) Net Margin % Explanation

Although Net Income and Earnings-per-Share (EPS) are the most widely used parameter in measuring a company's profitability and valuation, it is the least reliable. The reason is that reported earnings can be manipulated easily by adjusting any numbers such as Depreciation, Depletion and Amotorization and non-recurring items.

But the long term trend of the net margin is a good indicator of the competitiveness and health of the business.

SeaStar Medical Holding Net Margin % Related Terms

SeaStar Medical Holding Net Margin % Historical Data

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The historical data trend for SeaStar Medical Holding's Net Margin % can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

SeaStar Medical Holding Net Margin % Chart

SeaStar Medical Holding Annual Data

Trend

Dec20

Dec21

Dec22

Dec23

Dec24

Dec25

Net Margin %

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0.00

-18,392.59

-984.60

SeaStar Medical Holding Quarterly Data
	Mar21	Jun21	Dec21	Mar22	Jun22	Sep22	Dec22	Mar23	Jun23	Sep23	Dec23	Mar24	Jun24	Sep24	Dec24	Mar25	Jun25	Sep25	Dec25	Mar26
Net Margin %	Get a 7-Day Free Trial															-1,287.37	-592.31	-1,897.27	-691.43	-711.31

ICU vs MBRX, LEXX, INTI: Net Margin % Comparison

For the Biotechnology subindustry, SeaStar Medical Holding's Net Margin %, along with its competitors' market caps and Net Margin % data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.

SeaStar Medical Holding Net Margin % vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, SeaStar Medical Holding's Net Margin % distribution charts can be found below:

* The bar in red indicates where SeaStar Medical Holding's Net Margin % falls into.

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29GF Score

SeaStar Medical Holding Corp ICU

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SeaStar Medical Holding Net Margin % Calculation

Net margin - also known as net profit margin is the ratio of Net Income divided by net sales or Revenue, usually presented in percent.

SeaStar Medical Holding's Net Margin for the fiscal year that ended in Dec. 2025 is calculated as

Net Margin	=	Net Income (A: Dec. 2025 )	/	Revenue (A: Dec. 2025 )
	=	-12.15	/	1.234
	=	-984.60 %

SeaStar Medical Holding's Net Margin for the quarter that ended in Mar. 2026 is calculated as

Net Margin	=	Net Income (Q: Mar. 2026 )	/	Revenue (Q: Mar. 2026 )
	=	-3.521	/	0.495
	=	-711.31 %

Frequently Asked Questions Learn more about Net Margin % →

What does a Net Margin % of -711.31% mean?

SeaStar Medical Holding (ICU) has a Net Margin % of -711.31% as of Mar. 2026. Net margin is the ratio of total net income to net sales. View historical data on SeaStar Medical Holding and its competitors. According to the industry distribution chart, SeaStar Medical Holding ranks #727 out of 946 companies in the Biotechnology industry, placing it in the top 76.8%.

Is SeaStar Medical Holding's Net Margin % too high?

SeaStar Medical Holding's current Net Margin % is -711.31%. Based on the distribution chart, SeaStar Medical Holding ranks #727 out of 946 companies in the Biotechnology industry, which is in the bottom quartile relative to peers. Overall, SeaStar Medical Holding has a GF Score™ of 29/100, reflecting its overall financial health beyond just this single metric.

How does SeaStar Medical Holding's Net Margin % compare to MBRX and LEXX?

According to the Biotechnology industry distribution chart, SeaStar Medical Holding ranks #727 out of 946 companies for Net Margin %. This places SeaStar Medical Holding in the lower half of its industry. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.

What is a good Net Margin % for a Biotechnology company?

A good Net Margin % depends on the Biotechnology industry context. However, Net Margin % should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.

What does a high Net Margin % mean?

A high Net Margin % can signal that a stock is expensive relative to its fundamentals. Net margin is the ratio of total net income to net sales. View historical data on SeaStar Medical Holding and its competitors. SeaStar Medical Holding's current Net Margin % is -711.31%. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.

Is SeaStar Medical Holding stock overvalued right now?

SeaStar Medical Holding (ICU) has a current Net Margin % of -711.31%. The current Net Margin % is -711.31%. SeaStar Medical Holding's overall GF Score™ is 29/100 with 4 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.

How is Net Margin % calculated?

Net Margin % is calculated from a company's financial statements. For SeaStar Medical Holding (ICU), the current Net Margin % is -711.31% as of Mar. 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

SeaStar Medical Holding Business Description

Industry Healthcare Biotechnology

Comparable Companies MBRX LEXX INTI MTVA HCWB CVKD OSRH COCP HOOK LNAI VRTX REGN XBRU:UCB XBRU:ARGX XKRX:207940 ALNY RVMD ASX:CSL ONC XKRX:068270

Address 3513 Brighton Boulevard, Suite 410, Denver, CO, USA, 80216

Website https://www.seastarmedical.com

SeaStar Medical Holding Corp is a medical technology company developing proprietary solutions to reduce the consequences of hyperinflammation on vital organs. It is developing and commercializing extracorporeal therapies that target the effector cells that drive systemic inflammation, causing direct tissue damage and secreting a range of pro-inflammatory cytokines that initiate and propagate imbalanced immune responses. The Company is comprised of a single reportable segment, which is its Device Segment.

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