SeaStar Medical HoldingICU +9.06%29 PB Ratio is 1.77 as of Jun. 26, 2026, which is 14% below its 10-year median of 2.05. GuruFocus rates ICU with a GF Score™ of 29/100. The stock has 4 warning signs investors should review. Among 1,232 Biotechnology companies, SeaStar Medical Holding ranks better than 68.91% on this metric.
The historical rank and industry rank for SeaStar Medical Holding's PB Ratio or its related term are showing as below:
ICU'
s PB Ratio Range Over the Past 10 Years
Min: 0.73 Med: 2.05 Max: 22.79
Current: 1.78
During the past 6 years, SeaStar Medical Holding's highest PB Ratio was 22.79. The lowest was 0.73. And the median was 2.05.
ICU's PB Ratio is ranked better than 68.91% of 1232
companies
in the Biotechnology industry
Industry Median: 2.8
vs ICU: 1.78
During the past 12 months, SeaStar Medical Holding's average Book Value Per Share Growth Rate was 200.20% per year.
During the past 6 years, the highest 3-Year average Book Value Per Share Growth Rate of SeaStar Medical Holding was 62.70% per year. The lowest was 59.60% per year. And the median was 61.15% per year.
Back to Basics: PB Ratio
SeaStar Medical Holding (NAS:ICU) PB Ratio Explanation
The PB Ratio works the best for the businesses that earn most of their profit from their assets, e.g. banks and insurance companies.
Be Aware
Some businesses have very light assets, such as software companies or insurance agencies. The PB Ratio does not work well for these companies. Some companies even have negative equity, so the PB Ratio cannot be applied to them.
* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD. * For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.
For the Biotechnology subindustry, SeaStar Medical Holding's PB Ratio, along with its competitors' market caps and PB Ratio data, can be viewed below:
* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.
SeaStar Medical Holding PB Ratio vs Biotechnology Industry
For the Biotechnology industry and Healthcare sector, SeaStar Medical Holding's PB Ratio distribution charts can be found below:
* The bar in red indicates where SeaStar Medical Holding's PB Ratio falls into.
The PB Ratio, or Price-to-Book ratio, or Price/Book, is a financial ratio used to compare a company's market price to its Book Value per Share. It is a ratio widely used to value stocks.
* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD. * For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.
It can also be calculated from the numbers for the whole company:
A closely related ratio is called Price-to-Tangible-Book. The difference between Price-to-Tangible-Book and PB Ratio is that book value other than intangibles are used in the calculation.
SeaStar Medical Holding (ICU) has a PB Ratio of 1.77 as of Jun. 26, 2026. Price-to-Book ratio is the ratio of share price to a company's book value per share. View historical data on SeaStar Medical Holding and its competitors. This is 14% below median its historical median of 2.05. Over the past decade, SeaStar Medical Holding's PB Ratio has ranged from 0.73 to 22.79. According to the industry distribution chart, SeaStar Medical Holding ranks #383 out of 1232 companies in the Biotechnology industry, placing it in the top 31.1%.
Is SeaStar Medical Holding's PB Ratio too high?
SeaStar Medical Holding's current PB Ratio of 1.77 is 14% below median its 10-year median of 2.05. Over the past 10 years, this metric has ranged from a low of 0.73 to a high of 22.79. The Biotechnology industry median PB Ratio is 2.80. SeaStar Medical Holding's value of 1.77 is 36.8% below this industry median. Based on the distribution chart, SeaStar Medical Holding ranks #383 out of 1232 companies in the Biotechnology industry, which is above the industry midpoint. Overall, SeaStar Medical Holding has a GF Score™ of 29/100, reflecting its overall financial health beyond just this single metric.
How does SeaStar Medical Holding's PB Ratio compare to MBRX and LEXX?
According to the Biotechnology industry distribution chart, SeaStar Medical Holding ranks #383 out of 1232 companies for PB Ratio. This puts SeaStar Medical Holding in the upper half of its industry. The industry median PB Ratio is 2.80. SeaStar Medical Holding's value of 1.77 is 36.8% below this benchmark. Historically, SeaStar Medical Holding's own PB Ratio has ranged from 0.73 to 22.79 over the past decade. While the company's 10-year median is 2.05 vs. the industry median of 2.80, SeaStar Medical Holding has consistently been below the industry average. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good PB Ratio for a Biotechnology company?
The median PB Ratio among Biotechnology companies is 2.80, based on 1,232 companies in the industry. Companies in the top quartile (top 25%) have a PB Ratio significantly above this median, while those in the bottom quartile fall well below. However, PB Ratio should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. SeaStar Medical Holding's current PB Ratio of 1.77 is 36.8% below the industry median. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high PB Ratio mean?
A high PB Ratio can signal that a stock is expensive relative to its fundamentals. Price-to-Book ratio is the ratio of share price to a company's book value per share. View historical data on SeaStar Medical Holding and its competitors. For the Biotechnology industry, the median PB Ratio is 2.80 — values significantly above this may indicate overvaluation, while values below may suggest a bargain or underlying issues. SeaStar Medical Holding's current PB Ratio is 1.77, which is 14% below median its own 10-year median of 2.05. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is SeaStar Medical Holding stock overvalued right now?
SeaStar Medical Holding (ICU) has a current PB Ratio of 1.77. The current PB Ratio is 1.77, which is 14% below median its 10-year median of 2.05 and 36.8% below the Biotechnology industry median of 2.80. SeaStar Medical Holding's overall GF Score™ is 29/100 with 4 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is PB Ratio calculated?
PB Ratio is calculated from a company's financial statements. For SeaStar Medical Holding (ICU), the current PB Ratio is 1.77 as of Jun. 26, 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.
SeaStar Medical Holding Corp is a medical technology company developing proprietary solutions to reduce the consequences of hyperinflammation on vital organs. It is developing and commercializing extracorporeal therapies that target the effector cells that drive systemic inflammation, causing direct tissue damage and secreting a range of pro-inflammatory cytokines that initiate and propagate imbalanced immune responses. The Company is comprised of a single reportable segment, which is its Device Segment.
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