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Spyre Therapeutics's book value per share for the quarter that ended in Mar. 2026 was $6.53.
During the past 12 months, Spyre Therapeutics's average Book Value Per Share Growth Rate was 20.50% per year.
During the past 3 years, the average Book Value Per Share Growth Rate was -28.10% per year.
Please click Growth Rate Calculation Example (GuruFocus) to see how GuruFocus calculates Wal-Mart Stores Inc (WMT)'s revenue growth rate. You can apply the same method to get the book value growth rate using book value per share data.
During the past 13 years, the highest 3-Year average Book Value Per Share Growth Rate of Spyre Therapeutics was -1.10% per year. The lowest was -47.90% per year. And the median was -25.95% per year.
Spyre Therapeutics's current price is $105.00. Its book value per share for the quarter that ended in Mar. 2026 was $6.53. Hence, today's PB Ratio of Spyre Therapeutics is 16.07.
During the past 13 years, the highest P/B Ratio of Spyre Therapeutics was 16.07. The lowest was 0.25. And the median was 1.79.
Warning Sign:
Spyre Therapeutics Inc stock PB Ratio (=14.53) is close to 10-year high of 14.53.
Spyre Therapeutics (NAS:SYRE) Book Value per Share Explanation
Usually a company's book value and Tangible Book per Share may not reflect its true value. The assets may be carried on the balance sheets at the original cost minus depreciation. This may underestimate the true economic values of the assets. It also may over-estimate their true economic value because the assets can become obsolete.
For financial companies such as banks and insurance companies, their assets may be reported in current market value of the assets owned. Book values of financial companies are more accurate indicator of the economic value of the company.
Spyre Therapeutics Book Value per Share Related Terms
Spyre Therapeutics Book Value per Share Historical Data
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The historical data trend for Spyre Therapeutics's Book Value per Share can be seen below:
* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD. * For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.
SYRE vs CRNX, PTGX, PRAX: Book Value per Share Comparison
For the Biotechnology subindustry, Spyre Therapeutics's PB Ratio, along with its competitors' market caps and PB Ratio data, can be viewed below:
* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.
Spyre Therapeutics PB Ratio vs Biotechnology Industry
For the Biotechnology industry and Healthcare sector, Spyre Therapeutics's PB Ratio distribution charts can be found below:
* The bar in red indicates where Spyre Therapeutics's PB Ratio falls into.
* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD. * For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.
Spyre Therapeutics (SYRE) has a Book Value per Share of $6.53 as of Mar. 2026. Book value per share gives the per-share value of a company's stockholder equity. View historical data on Spyre Therapeutics and its competitors.
Is Spyre Therapeutics' Book Value per Share too high?
Spyre Therapeutics' current Book Value per Share is $6.53. Overall, Spyre Therapeutics has a GF Score™ of 26/100, reflecting its overall financial health beyond just this single metric.
How does Spyre Therapeutics' Book Value per Share compare to CRNX and PTGX?
Spyre Therapeutics' Book Value per Share of $6.53 can be compared against companies in the Biotechnology industry. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good Book Value per Share for a Biotechnology company?
A good Book Value per Share depends on the Biotechnology industry context. However, Book Value per Share should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high Book Value per Share mean?
A high Book Value per Share can signal that a stock is expensive relative to its fundamentals. Book value per share gives the per-share value of a company's stockholder equity. View historical data on Spyre Therapeutics and its competitors. Spyre Therapeutics's current Book Value per Share is $6.53. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Spyre Therapeutics stock overvalued right now?
Spyre Therapeutics (SYRE) has a current Book Value per Share of $6.53. The current Book Value per Share is $6.53. Spyre Therapeutics' overall GF Score™ is 26/100 with 4 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is Book Value per Share calculated?
Book Value per Share is calculated from a company's financial statements. For Spyre Therapeutics (SYRE), the current Book Value per Share is $6.53 as of Mar. 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.
Spyre Therapeutics Inc is a clinical-stage biotechnology company pioneering long-acting antibodies and antibody combinations to redefine the standard of care for inflammatory bowel disease (IBD) and rheumatic diseases. Spyre's pipeline includes extended half-life antibodies targeting ?4?7, TL1A, and IL-23 in development as monotherapies and pair-wise combinations. It has a single reportable segment, which is the development of biopharmaceutical products for the treatment of patients with IBD and other immune-mediated disease.
26GF Score
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