PRME (Prime Medicine) YoY EPS Growth: 41.46% (As of Jun. 2026)

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PRME Prime Medicine Inc PRME
33 GF Score
Price $3.20
! 3 Warning Signs
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What is Prime Medicine YoY EPS Growth?

Prime Medicine PRME -1.84% 33 YoY EPS Growth is 41.46% as of Jun. 2026. GuruFocus rates PRME with a GF Score™ of 33/100. The stock has 3 warning signs investors should review.

YoY EPS Growth is the percentage change of Earnings per Share (Diluted) over the past twelve months. Prime Medicine's YoY EPS Growth for the quarter that ended in Jun. 2026 was 41.46%.

Prime Medicine's Earnings per Share (Diluted) for the three months ended in Jun. 2026 was $-0.24.

Prime Medicine YoY EPS Growth Historical Data

* Premium members only.

The historical data trend for Prime Medicine's YoY EPS Growth can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Prime Medicine YoY EPS Growth Chart

Prime Medicine Annual Data
Trend Dec20 Dec21 Dec22 Dec23 Dec24 Dec25
YoY EPS Growth
Get a 7-Day Free Trial -3,562.86 -63.42 47.97 24.31 18.18

Prime Medicine Quarterly Data
Sep21 Dec21 Mar22 Jun22 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Sep24 Dec24 Mar25 Jun25 Sep25 Dec25 Mar26 Jun26
YoY EPS Growth Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only 10.87 27.27 22.58 30.00 41.46
PRME
33GF Score
Prime Medicine Inc PRME
YoY EPS Growth is just one metric. See GF Score™, valuation, warning signs, and more.
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Prime Medicine YoY EPS Growth Calculation

YoY EPS Growth is the percentage change of Earnings per Share (Diluted) over the past twelve months.

Prime Medicine's YoY EPS Growth for the fiscal year that ended in Dec. 2025 is calculated as:

YoY EPS Growth (A: Dec. 2025 )
=(Earnings per Share (Diluted) (A: Dec. 2025 )-Earnings per Share (Diluted) (A: Dec. 2024 ))/ | Earnings per Share (Diluted) (A: Dec. 2024 ) |
=(-1.35--1.65)/ | -1.65 |
=18.18 %

Prime Medicine's YoY EPS Growth for the quarter that ended in Jun. 2026 is calculated as:

YoY EPS Growth (Q: Jun. 2026 )
=(Earnings per Share (Diluted) (Q: Jun. 2026 )-Earnings per Share (Diluted) (Q: Jun. 2025 )) / | Earnings per Share (Diluted) (Q: Jun. 2025 )) |
=(-0.24--0.41)/ | -0.41 |
=41.46 %

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Frequently Asked Questions Learn more about YoY EPS Growth →
What does a YoY EPS Growth of 41.46% mean?
Prime Medicine (PRME) has a YoY EPS Growth of 41.46% as of Jun. 2026. YoY EPS Growth is the percentage change of EPS over the past 12-month. View historical data for Prime Medicine and its competitors.
Is Prime Medicine's YoY EPS Growth too high?
Prime Medicine's current YoY EPS Growth is 41.46%. Overall, Prime Medicine has a GF Score™ of 33/100, reflecting its overall financial health beyond just this single metric.
How does Prime Medicine's YoY EPS Growth compare to VSTM and ALT?
Prime Medicine's YoY EPS Growth of 41.46% can be compared against companies in the Biotechnology industry. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good YoY EPS Growth for a Biotechnology company?
A good YoY EPS Growth depends on the Biotechnology industry context. However, YoY EPS Growth should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high YoY EPS Growth mean?
A high YoY EPS Growth can signal that a stock is expensive relative to its fundamentals. YoY EPS Growth is the percentage change of EPS over the past 12-month. View historical data for Prime Medicine and its competitors. Prime Medicine's current YoY EPS Growth is 41.46%. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Prime Medicine stock overvalued right now?
Prime Medicine (PRME) has a current YoY EPS Growth of 41.46%. The current YoY EPS Growth is 41.46%. Prime Medicine's overall GF Score™ is 33/100 with 3 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is YoY EPS Growth calculated?
YoY EPS Growth is calculated from a company's financial statements. For Prime Medicine (PRME), the current YoY EPS Growth is 41.46% as of Jun. 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Prime Medicine Business Description

Address 60 First Street, Cambridge, MA, USA, 02141
Prime Medicine Inc is a biotechnology company focused on developing a new class of genetic medicines designed to provide durable, and potentially curative, treatment options for patients with diseases driven by defined genetic alterations, acquired cellular dysfunction, or dysregulated gene expression. Its program, PM577 for Wilson Disease, is designed to initially correct the H1069Q mutation in the ATP7B gene and is supported by preclinical data showing targeted correction and restoration of copper homeostasis in animal models. In addition, PM647 is being developed for alpha-1 antitrypsin deficiency, or AATD, another liver targeted disease with substantial unmet need.
33GF Score

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