UPB (Upstream Bio) Net Income (Continuing Operations): $-156.50 Mil (TTM As of Jun. 2026)

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UPB Upstream Bio Inc UPB
13 GF Score
Price $6.96
! 3 Warning Signs
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What is Upstream Bio Net Income (Continuing Operations)?

Upstream Bio UPB +1.75% 13 Net Income (Continuing Operations) is $-156.50 Mil as of Jun. 2026. GuruFocus rates UPB with a GF Score™ of 13/100. The stock has 3 warning signs investors should review.

Net Income (Continuing Operations) indicates the net income that a firm brings in from ongoing business activities. These activities are expected to continue into the next reporting period. Upstream Bio's Net Income (Continuing Operations) for the three months ended in Jun. 2026 was $-39.70 Mil. Its Net Income (Continuing Operations) for the trailing twelve months (TTM) ended in Jun. 2026 was $-156.50 Mil.

Upstream Bio  (NAS:UPB) Net Income (Continuing Operations) Explanation

Net Income (Continuing Operations) excludes extraordinary items, income from the cumulative effects of accounting changes, non-recurring items, income from tax loss carry forward, and preferred dividends.

Upstream Bio Net Income (Continuing Operations) Related Terms

Upstream Bio Net Income (Continuing Operations) Historical Data

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The historical data trend for Upstream Bio's Net Income (Continuing Operations) can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Upstream Bio Net Income (Continuing Operations) Chart

Upstream Bio Annual Data
Trend Dec22 Dec23 Dec24 Dec25
Net Income (Continuing Operations)
-23.87 -20.54 -62.81 -143.44

Upstream Bio Quarterly Data
Dec22 Sep23 Dec23 Mar24 Jun24 Sep24 Dec24 Mar25 Jun25 Sep25 Dec25 Mar26 Jun26
Net Income (Continuing Operations) Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only -39.97 -33.75 -42.46 -40.59 -39.70
UPB
13GF Score
Upstream Bio Inc UPB
Net Income (Continuing Operations) is just one metric. See GF Score™, valuation, warning signs, and more.
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Upstream Bio Net Income (Continuing Operations) Calculation

Net Income (Continuing Operations) indicates the net income that a firm brings in from ongoing business activities. These activities are expected to continue into the next reporting period.

Net Income (Continuing Operations) for the trailing twelve months (TTM) ended in Jun. 2026 adds up the quarterly data reported by the company within the most recent 12 months, which was $-156.50 Mil.

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

What does a Net Income (Continuing Operations) of $-156.50 Mil mean?
Upstream Bio (UPB) has a Net Income (Continuing Operations) of $-156.50 Mil as of Jun. 2026. Net Income (Continuing operations) is the total net earnings from a company's continuing operations. View historical data on Upstream Bio and its competitors.
Is Upstream Bio's Net Income (Continuing Operations) too high?
Upstream Bio's current Net Income (Continuing Operations) is $-156.50 Mil. Overall, Upstream Bio has a GF Score™ of 13/100, reflecting its overall financial health beyond just this single metric.
How does Upstream Bio's Net Income (Continuing Operations) compare to RCKT and ABEO?
Upstream Bio's Net Income (Continuing Operations) of $-156.50 Mil can be compared against companies in the Biotechnology industry. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good Net Income (Continuing Operations) for a Biotechnology company?
A good Net Income (Continuing Operations) depends on the Biotechnology industry context. However, Net Income (Continuing Operations) should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high Net Income (Continuing Operations) mean?
A high Net Income (Continuing Operations) can signal that a stock is expensive relative to its fundamentals. Net Income (Continuing operations) is the total net earnings from a company's continuing operations. View historical data on Upstream Bio and its competitors. Upstream Bio's current Net Income (Continuing Operations) is $-156.50 Mil. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Upstream Bio stock overvalued right now?
Upstream Bio (UPB) has a current Net Income (Continuing Operations) of $-156.50 Mil. The current Net Income (Continuing Operations) is $-156.50 Mil. Upstream Bio's overall GF Score™ is 13/100 with 3 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is Net Income (Continuing Operations) calculated?
Net Income (Continuing Operations) is calculated from a company's financial statements. For Upstream Bio (UPB), the current Net Income (Continuing Operations) is $-156.50 Mil as of Jun. 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Upstream Bio Business Description

Address 890 Winter Street, Suite 200, Waltham, MA, USA, 02451
Upstream Bio Inc is a clinical-stage biotechnology company developing treatments for inflammatory diseases, with an initial focus on severe respiratory disorders. It is developing verekitug, the known antagonist currently in clinical development that targets the receptor for Thymic Stromal Lymphopoietin (TSLP), a cytokine that is a clinically validated driver of inflammatory response positioned upstream of multiple signaling cascades that affect a variety of immune-mediated diseases. Verekitug has advanced into three separate world-wide, placebo-controlled, randomized Phase 2 clinical trials, two completed in chronic rhinosinusitis with nasal polyps (CRSwNP) and severe asthma, and one ongoing in chronic obstructive pulmonary disease (COPD).
13GF Score

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Net Income (Continuing Operations) is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

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