SPRB (Spruce Biosciences) EBIT per Share: $-37.04 (TTM As of Mar. 2026)


SPRB Spruce Biosciences Inc SPRB
40 GF Score
Price $52.51
GF Value $4.08
Valuation Significantly Overvalued
! 1 Warning Sign
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What is Spruce Biosciences EBIT per Share?

Spruce Biosciences SPRB -0.07% 40 EBIT per Share is $-37.04 as of Mar. 2026. GuruFocus rates SPRB with a GF Score™ of 40/100 and a GF Value™ of $4.08 (Significantly Overvalued). The stock has 1 warning sign investors should review. Among 1,178 Biotechnology companies, Spruce Biosciences ranks better than 70.97% on this metric.

Spruce Biosciences's EBIT per Share for the three months ended in Mar. 2026 was $-8.45. Its EBIT per Share for the trailing twelve months (TTM) ended in Mar. 2026 was $-37.04.

During the past 3 years, the average EBIT per Share Growth Rate was 31.90% per year. During the past 5 years, the average EBIT per Share Growth Rate was 27.90% per year. Please click Growth Rate Calculation Example (GuruFocus) to see how GuruFocus calculates Wal-Mart Stores Inc (WMT)'s revenue growth rate. You can apply the same method to get the EBIT per Share growth rate using EBIT per Share data.

The historical rank and industry rank for Spruce Biosciences's EBIT per Share or its related term are showing as below:

SPRB' s 3-Year EBIT Growth Rate Range Over the Past 10 Years
Min: -11.9   Med: 9   Max: 34.9
Current: 31.9

During the past 8 years, the highest 3-Year average EBIT per Share Growth Rate of Spruce Biosciences was 34.90% per year. The lowest was -11.90% per year. And the median was 9.00% per year.

SPRB's 3-Year EBIT Growth Rate is ranked better than
70.97% of 1178 companies
in the Biotechnology industry
Industry Median: 15.55 vs SPRB: 31.90

Spruce Biosciences's EBIT for the three months ended in Mar. 2026 was $-11.59 Mil.


Spruce Biosciences  (NAS:SPRB) EBIT per Share Explanation

EBIT is a company's earnings before interest and tax expenses are deducted. It measures a company's profit generates from operating, ignoring tax burden and capital structure. As the tax expense are not deducted, EBIT is helpful when comparing companies in the same industry but with different tax situations. Also, the interest expense are included in EBIT, making it useful to compare companies that have high interest expenses due to large amount of debt.


Spruce Biosciences EBIT per Share Related Terms


Spruce Biosciences EBIT per Share Historical Data

* Premium members only.

The historical data trend for Spruce Biosciences's EBIT per Share can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Spruce Biosciences EBIT per Share Chart

Spruce Biosciences Annual Data
Trend Dec18 Dec19 Dec20 Dec21 Dec22 Dec23 Dec24 Dec25
EBIT per Share
Get a 7-Day Free Trial -134.88 -145.73 -92.47 -95.87 -50.69

Spruce Biosciences Quarterly Data
Jun21 Sep21 Dec21 Mar22 Jun22 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Sep24 Dec24 Mar25 Jun25 Sep25 Dec25 Mar26
EBIT per Share Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only -23.90 -3.36 -14.55 -10.67 -8.45
SPRB
40GF Score
Spruce Biosciences Inc SPRB
EBIT per Share is just one metric. See GF Score™, valuation, warning signs, and more.
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Spruce Biosciences EBIT per Share Calculation

EBIT per Share is the amount of Earnings Before Interest and Taxes (EBIT) per outstanding share of the company's stock.

Earnings Before Interest and Taxes (EBIT) is what the company earns before it expenses interest and taxes.

Spruce Biosciences's EBIT per Share for the fiscal year that ended in Dec. 2025 is calculated as

EBIT per Share(A: Dec. 2025 )
=EBIT/Shares Outstanding (Diluted Average)
=-38.876/0.767
=-50.69

Spruce Biosciences's EBIT per Share for the quarter that ended in Mar. 2026 is calculated as

EBIT per Share(Q: Mar. 2026 )
=EBIT/Shares Outstanding (Diluted Average)
=-11.592/1.372
=-8.45

EBIT per Share for the trailing twelve months (TTM) ended in Mar. 2026 adds up the quarterly data reported by the company within the most recent 12 months, which was $-37.04

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Frequently Asked Questions Learn more about EBIT per Share →
What does a EBIT per Share of $-37.04 mean?
Spruce Biosciences (SPRB) has a EBIT per Share of $-37.04 as of Mar. 2026. EBIT per Share is the amount of Earnings Before Interest and Taxes per outstanding share of the company's stock. View historical data on Spruce Biosciences and its competitors. According to the industry distribution chart, Spruce Biosciences ranks #342 out of 1178 companies in the Biotechnology industry, placing it in the top 29%.
Is Spruce Biosciences' EBIT per Share too high?
Spruce Biosciences' current EBIT per Share is $-37.04. Based on the distribution chart, Spruce Biosciences ranks #342 out of 1178 companies in the Biotechnology industry, which is above the industry midpoint. Overall, Spruce Biosciences has a GF Score™ of 40/100 and is considered Significantly Overvalued, reflecting its overall financial health beyond just this single metric.
How does Spruce Biosciences' EBIT per Share compare to TLSA and MIST?
According to the Biotechnology industry distribution chart, Spruce Biosciences ranks #342 out of 1178 companies for EBIT per Share. This puts Spruce Biosciences in the upper half of its industry. The industry median EBIT per Share is 15.55. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good EBIT per Share for a Biotechnology company?
The median EBIT per Share among Biotechnology companies is 15.55, based on 1,178 companies in the industry. Companies in the top quartile (top 25%) have a EBIT per Share significantly above this median, while those in the bottom quartile fall well below. However, EBIT per Share should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high EBIT per Share mean?
A high EBIT per Share can signal that a stock is expensive relative to its fundamentals. EBIT per Share is the amount of Earnings Before Interest and Taxes per outstanding share of the company's stock. View historical data on Spruce Biosciences and its competitors. For the Biotechnology industry, the median EBIT per Share is 15.55 — values significantly above this may indicate overvaluation, while values below may suggest a bargain or underlying issues. Spruce Biosciences's current EBIT per Share is $-37.04. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Spruce Biosciences stock overvalued right now?
Based on GuruFocus' analysis, Spruce Biosciences (SPRB) is currently considered Significantly Overvalued. The stock's GF Value™ is $4.08, compared to a current price of $52.51 — trading 1187% above its estimated fair value. The current EBIT per Share is $-37.04. Spruce Biosciences' overall GF Score™ is 40/100 with 1 warning sign to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is EBIT per Share calculated?
EBIT per Share is calculated from a company's financial statements. For Spruce Biosciences (SPRB), the current EBIT per Share is $-37.04 as of Mar. 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Is Spruce Biosciences (SPRB) Overvalued in 2026?

Based on GuruFocus' analysis, Spruce Biosciences stock appears to be overvalued. The current stock price of $52.51 is trading 1187% above its estimated GF Value™ of $4.08. GuruFocus considers Spruce Biosciences to be Significantly Overvalued.

Key valuation signals for SPRB:

  • EBIT per Share: $-37.04
  • GF Value™: $4.08 vs. price of $52.51 (1187% above fair value)
  • GF Score™: 40/100 with 1 warning sign

No single metric tells the full story. See the SPRB stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.


Spruce Biosciences Business Description

Address 611 Gateway Boulevard, Suite 740, South San Francisco, CA, USA, 94080
Spruce Biosciences Inc is a late-stage biopharmaceutical company focused on developing and commercializing novel therapies for rare endocrine disorders with unmet medical needs. The company develops biologics and small-molecule product candidates aimed at addressing diseases with unmet medical needs and limited or no approved therapies. Its product candidate, TA-ERT for the treatment of Mucopolysaccharidosis Type IIIB (MPS IIIB), is a fusion protein comprised of recombinant human alpha-N-acetylglucosaminidase (rhNAGLU) intended as an enzyme replacement therapy for patients who lack rhNAGLU enzyme activity. TA-ERT is designed to restore rhNAGLU enzyme activity in the central nervous system following intracerebroventricular injection and promote clearance of heparan sulfate in the brain.
40GF Score

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EBIT per Share is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

$52.51
Price
$4.08
GF Value