SEPN (Septerna) Ending Cash Position: $85.57 Mil (As of Jun. 2026)

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SEPN Septerna Inc SEPN
12 GF Score
Price $40.50
! 4 Warning Signs
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What is Septerna Ending Cash Position?

Septerna SEPN +1.30% 12 Ending Cash Position is $85.57 Mil as of Jun. 2026. GuruFocus rates SEPN with a GF Score™ of 12/100. The stock has 4 warning signs investors should review.

Septerna's Ending Cash Position for the quarter that ended in Jun. 2026 was $85.57 Mil.

Septerna's quarterly Ending Cash Position declined from Dec. 2025 ($121.63 Mil) to Mar. 2026 ($72.51 Mil) but then increased from Mar. 2026 ($72.51 Mil) to Jun. 2026 ($85.57 Mil).

Septerna's annual Ending Cash Position increased from Dec. 2023 ($89.39 Mil) to Dec. 2024 ($239.10 Mil) but then declined from Dec. 2024 ($239.10 Mil) to Dec. 2025 ($121.63 Mil).

Septerna Ending Cash Position Related Terms

Septerna Ending Cash Position Historical Data

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The historical data trend for Septerna's Ending Cash Position can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Septerna Ending Cash Position Chart

Septerna Annual Data
Trend Dec22 Dec23 Dec24 Dec25
Ending Cash Position
31.47 89.39 239.10 121.63

Septerna Quarterly Data
Dec22 Sep23 Dec23 Mar24 Jun24 Sep24 Dec24 Mar25 Jun25 Sep25 Dec25 Mar26 Jun26
Ending Cash Position Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only 190.22 320.89 121.63 72.51 85.57
SEPN
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Septerna Inc SEPN
Ending Cash Position is just one metric. See GF Score™, valuation, warning signs, and more.
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Septerna Ending Cash Position Calculation

Ending Cash Position is the cash and cash equivalents balance at the end of the accounting period, as indicated on the Cash Flow statement. It is equal to the Beginning Cash Position plus the Net Change in Cash.

Septerna's Ending Cash Position for the fiscal year that ended in Dec. 2025 is calculated as

Ending Cash Position= Beginning Cash Position+Net Change in Cash
=239.101+-117.474
=121.63

Septerna's Ending Cash Position for the quarter that ended in Jun. 2026 is calculated as

Ending Cash Position=Beginning Cash Position+Net Change in Cash
=72.51+13.057
=85.57

Frequently Asked Questions Learn more about Ending Cash Position →
What does a Ending Cash Position of $85.57 Mil mean?
Septerna (SEPN) has a Ending Cash Position of $85.57 Mil as of Jun. 2026. Ending Cash Position is the cash and cash equivalents balance at the end of the accounting period, as indicated on the Cash Flow statement. View historical data on Septerna and its competitors.
Is Septerna's Ending Cash Position too high?
Septerna's current Ending Cash Position is $85.57 Mil. Overall, Septerna has a GF Score™ of 12/100, reflecting its overall financial health beyond just this single metric.
How does Septerna's Ending Cash Position compare to NTLA and AVBP?
Septerna's Ending Cash Position of $85.57 Mil can be compared against companies in the Biotechnology industry. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good Ending Cash Position for a Biotechnology company?
A good Ending Cash Position depends on the Biotechnology industry context. However, Ending Cash Position should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high Ending Cash Position mean?
A high Ending Cash Position can signal that a stock is expensive relative to its fundamentals. Ending Cash Position is the cash and cash equivalents balance at the end of the accounting period, as indicated on the Cash Flow statement. View historical data on Septerna and its competitors. Septerna's current Ending Cash Position is $85.57 Mil. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Septerna stock overvalued right now?
Septerna (SEPN) has a current Ending Cash Position of $85.57 Mil. The current Ending Cash Position is $85.57 Mil. Septerna's overall GF Score™ is 12/100 with 4 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is Ending Cash Position calculated?
Ending Cash Position is calculated from a company's financial statements. For Septerna (SEPN), the current Ending Cash Position is $85.57 Mil as of Jun. 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Septerna Business Description

Address 250 East Grand Avenue, South San Francisco, CA, USA, 94080
Septerna Inc is a clinical-stage biotechnology company pioneering a new era of G protein-coupled receptor (GPCR) oral small molecule drug discovery powered by a proprietary Native Complex Platform. Its industrial-scale platform aims to unlock the full potential of GPCR therapies. The group discovery and development of a pipeline of product candidates focused initially on treating patients in three therapeutic areas: endocrinology, immunology and inflammation, and metabolic disease. Its pipeline includes SEP-786 (PTH1R), SEP-631 (MRGPRX2), TSHR, GLP-1R, GIPR, and GCGR.
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