SEPN (Septerna) Institutional Ownership: 101.84% (As of Aug. 08, 2026)

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SEPN Septerna Inc SEPN
12 GF Score
Price $38.83
! 4 Warning Signs
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What is Septerna Institutional Ownership?

Septerna SEPN -1.77% 12 Institutional Ownership is 101.84% as of Aug. 08, 2026. GuruFocus rates SEPN with a GF Score™ of 12/100. The stock has 4 warning signs investors should review.

Institutional ownership is the percentage of shares that are owned by institutions out of the total shares outstanding. As of today, Septerna's institutional ownership is 101.84%.

Insider Ownership is the percentage of shares that are owned by company insiders relative to the total shares outstanding. As of today, Septerna's Insider Ownership is 2.89%.

Float Percentage Of Total Shares Outstanding is the percentage of float shares relative to the total shares outstanding. As of today, Septerna's Float Percentage Of Total Shares Outstanding is 50.62%.

Septerna Institutional Ownership Historical Data

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The historical data trend for Septerna's Institutional Ownership can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Septerna Institutional Ownership Chart

Septerna Historical Data

The historical data trend for Septerna can be seen below:

2025-10-31 2025-11-30 2025-12-31 2026-01-31 2026-02-28 2026-03-31 2026-04-30 2026-05-31 2026-06-30 2026-07-31
Institutional Ownership 18.35 18.44 20.16 20.30 20.28 21.36 20.32 20.34 21.39 22.21
SEPN
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Septerna Inc SEPN
Institutional Ownership is just one metric. See GF Score™, valuation, warning signs, and more.
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Septerna Institutional Ownership Calculation

The percentage of shares that are owned by institutions out of the total shares outstanding.

What does a Institutional Ownership of 101.84% mean?
Septerna (SEPN) has a Institutional Ownership of 101.84% as of Aug. 08, 2026. Institutional ownership equals the percent of shares owned by financial institutions relative to total shares. View historical data on Septerna and its competitors.
Is Septerna's Institutional Ownership too high?
Septerna's current Institutional Ownership is 101.84%. Overall, Septerna has a GF Score™ of 12/100, reflecting its overall financial health beyond just this single metric.
How does Septerna's Institutional Ownership compare to NTLA and AVBP?
Septerna's Institutional Ownership of 101.84% can be compared against companies in the Biotechnology industry. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good Institutional Ownership for a Biotechnology company?
A good Institutional Ownership depends on the Biotechnology industry context. However, Institutional Ownership should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high Institutional Ownership mean?
A high Institutional Ownership can signal that a stock is expensive relative to its fundamentals. Institutional ownership equals the percent of shares owned by financial institutions relative to total shares. View historical data on Septerna and its competitors. Septerna's current Institutional Ownership is 101.84%. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Septerna stock overvalued right now?
Septerna (SEPN) has a current Institutional Ownership of 101.84%. The current Institutional Ownership is 101.84%. Septerna's overall GF Score™ is 12/100 with 4 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is Institutional Ownership calculated?
Institutional Ownership is calculated from a company's financial statements. For Septerna (SEPN), the current Institutional Ownership is 101.84% as of Aug. 08, 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Septerna Business Description

Address 250 East Grand Avenue, South San Francisco, CA, USA, 94080
Septerna Inc is a clinical-stage biotechnology company pioneering a new era of G protein-coupled receptor (GPCR) oral small molecule drug discovery powered by a proprietary Native Complex Platform. Its industrial-scale platform aims to unlock the full potential of GPCR therapies. The group discovery and development of a pipeline of product candidates focused initially on treating patients in three therapeutic areas: endocrinology, immunology and inflammation, and metabolic disease. Its pipeline includes SEP-786 (PTH1R), SEP-631 (MRGPRX2), TSHR, GLP-1R, GIPR, and GCGR.
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Institutional Ownership is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

$38.83
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